Jason Allen Lowry

Works (1)

Updated: July 5th, 2023 16:02

2000 journal article

Molecular evolution of the GATA family of transcription factors: Conservation within the DNA-binding domain

JOURNAL OF MOLECULAR EVOLUTION, 50(2), 103–115.

By: J. Lowry n & W. Atchley n

author keywords: GATA; transcription factor; zinc finger; DNA binding domain; phylogeny; Boltzmann entropy; predictive motif
MeSH headings : Amino Acid Motifs; Amino Acid Sequence; Binding Sites; Conserved Sequence; DNA-Binding Proteins / physiology; Erythroid-Specific DNA-Binding Factors; Evolution, Molecular; Models, Molecular; Molecular Sequence Data; Phylogeny; Protein Structure, Tertiary; Transcription Factors / physiology; Zinc Fingers
TL;DR: It is shown that only the C-terminal zinc finger and basic domain, which together constitute the GATA-binding domain, are conserved throughout this protein family, and multiple modes of evolution are suggested, including gene duplication and modular evolution of GATA factors based upon inclusion of a class IV zinc finger motif. (via Semantic Scholar)
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
15. Life on Land (OpenAlex)
Source: Web Of Science
Added: August 6, 2018

Citation Index includes data from a number of different sources. If you have questions about the sources of data in the Citation Index or need a set of data which is free to re-distribute, please contact us.

Certain data included herein are derived from the Web of Science© and InCites© (2025) of Clarivate Analytics. All rights reserved. You may not copy or re-distribute this material in whole or in part without the prior written consent of Clarivate Analytics.