Sergey V. Nuzhdin

Works (13)

Updated: August 16th, 2024 13:38

2001 journal article

Quantitative trait locus mapping of fitness-related traits in Drosophila melanogaster

GENETICAL RESEARCH, 77(1), 107–116.

By: M. Wayne n, J. Hackett n, C. Dilda n, S. Nuzhdin*, E. Pasyukova* & T. MacKay  n

MeSH headings : Analysis of Variance; Animals; Body Constitution / genetics; Chromosome Mapping; DNA Transposable Elements; Drosophila melanogaster / genetics; Environment; Female; Fertility / genetics; Genetic Markers; Genetic Variation; Genotype; Inbreeding; Male; Quantitative Trait, Heritable; Recombination, Genetic; Sex Factors; Time Factors
TL;DR: There was significant genetic variation segregating in this cross for ovariole number, but not for body size or early fecundity, and Quantitative trait loci affecting female reproductive success and ovarioel number were mapped using a composite interval mapping procedure. (via Semantic Scholar)
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13. Climate Action (Web of Science)
Source: Web Of Science
Added: August 6, 2018

1999 journal article

High-resolution mapping of quantitative trait loci for sternopleural bristle number in Drosophila melanogaster

Genetics, 152(4), 1585–1604.

By: M. Gurganus, S. Nuzhdin, J. Leips & T. Mackay

Source: NC State University Libraries
Added: August 6, 2018

1999 journal article

New estimates of the rates and effects of mildly deleterious mutation in Drosophila melanogaster

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 96(2), 574–579.

By: J. Fry n, P. Keightley  n, S. Heinsohn n & S. Nuzhdin n

MeSH headings : Analysis of Variance; Animals; Chromosomes / genetics; Crosses, Genetic; Drosophila melanogaster / genetics; Environment; Genetics, Population; Genotype; Models, Genetic; Mortality; Mutation / genetics
TL;DR: The results suggest that the rate of mutations that detectably reduce viability may not be much greater than the lethal mutation rate (0.01 in these lines), but the results also are consistent with models that include many mutations with very small effects. (via Semantic Scholar)
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UN Sustainable Development Goal Categories
13. Climate Action (Web of Science)
15. Life on Land (Web of Science)
Source: Web Of Science
Added: August 6, 2018

1999 journal article

The genetic architecture of selection response: Inferences from fine-scale mapping of bristle number quantitative trait loci in Drosophila melanogaster

Genetics, 153(3), 1317–1331.

By: S. Nuzhdin, C. Dilda & T. Mackay

Source: NC State University Libraries
Added: August 6, 2018

1998 journal article

Genotype-environment interaction at quantitative trait loci affecting sensory bristle number in Drosophila melanogaster

Genetics, 149(4), 1883–1898.

By: M. Gurganus, J. Fry, S. Nuzhdin, E. Pasyukova, R. Lyman & T. MacKay

Source: NC State University Libraries
Added: August 6, 2018

1998 journal article

Mapping quantitative trait loci affecting sternopleural bristle number in Drosophila melanogaster using changes of marker allele frequencies in divergently selected lines

GENETICS RESEARCH, 72(2), 79–91.

By: S. Nuzhdin n, P. Keightley *, E. Pasyukova* & E. Morozova *

MeSH headings : Alleles; Animals; Chromosome Mapping / methods; Drosophila melanogaster / genetics; Gene Frequency; Genes, Insect; Genetic Markers; Models, Genetic; Monte Carlo Method; Selection, Genetic; Sense Organs / physiology
TL;DR: A permutation test of the correspondence between the mapped QTLs and the positions of bristle number candidate genes suggested that alleles at these candidate genes were no more strongly associated with selected changes in marker allele frequency than were randomly chosen positions in the genome. (via Semantic Scholar)
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
13. Climate Action (Web of Science)
15. Life on Land (Web of Science)
Source: Web Of Science
Added: August 6, 2018

1998 journal article

QTL mapping of genotype-environment interaction for fitness in Drosophila melanogaster

GENETICS RESEARCH, 71(2), 133–141.

By: J. Fry n, S. Nuzhdin n, E. Pasyukova n & T. Mckay

MeSH headings : Animals; Chromosome Mapping; Drosophila melanogaster / genetics; Genetic Variation; Genotype; Quantitative Trait, Heritable
TL;DR: It is suggested that antagonistic pleiotropy is a relatively uncommon form of genotype-environment interaction for fitness, but additional studies of natural populations are needed to confirm this conclusion. (via Semantic Scholar)
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UN Sustainable Development Goal Categories
2. Zero Hunger (Web of Science)
13. Climate Action (Web of Science)
15. Life on Land (Web of Science)
Source: Web Of Science
Added: August 6, 2018

1998 journal article

The relationship between the rate of transposition and transposable element copy number for copia and Doc retrotransposons of Drosophila melanogaster

GENETICS RESEARCH, 72(1), 1–11.

By: E. Pasyukova n, S. Nuzhdin n & D. Filatov *

MeSH headings : Animals; Drosophila melanogaster / genetics; Drosophila melanogaster / physiology; Female; Gene Dosage; Male; Retroelements / genetics
TL;DR: Overall, correlation between copia and Doc transposition rate and their copy number in the genome, if any, was not negative, and this fact is in agreement with the hypothesis that a positive correlation between the rate of transposition and TE copy number may be a default starting point for future host-TE coevolution. (via Semantic Scholar)
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Source: Web Of Science
Added: August 6, 2018

1997 article

Accumulation of transposable elements in laboratory lines of Drosophila melanogaster

GENETICA, Vol. 100, pp. 167–175.

By: S. Nuzhdin n, E. Pasyukova* & T. Mackay n

TL;DR: Inferences about the properties of spontaneous mutations from studies of mutation accumulation in laboratory lines should be reevaluated, because they are based on the assumption of a constant mutation rate. (via Semantic Scholar)
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UN Sustainable Development Goal Categories
15. Life on Land (OpenAlex)
Source: Web Of Science
Added: August 6, 2018

1997 journal article

Germ line transposition of the copia retrotransposon in Drosophila melanogaster is restricted to males by tissue-specific control of copia RNA levels

Molecular and General Genetics, 255(1), 115–124.

By: E. Pasyukova, S. Nuzhdin, W. Li & A. Flavell

Source: NC State University Libraries
Added: August 6, 2018

1997 journal article

Sex-specific quantitative trait loci affecting longevity in Drosophila melanogaster

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 94(18), 9734–9739.

By: S. Nuzhdin n, E. Pasyukova n, C. Dilda n, Z. Zeng n & T. Mackay n

MeSH headings : Animals; Drosophila melanogaster / genetics; Female; Genes, Insect; Longevity / genetics; Male; Mutation; Sex Determination Analysis
TL;DR: Late age-of-onset QTL effects are consistent with the mutation accumulation hypothesis for the evolution of senescence, and sex-specificQTL effects suggest a novel mechanism for maintaining genetic variation for lifespan. (via Semantic Scholar)
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Source: Web Of Science
Added: August 6, 2018

1995 journal article

Polygenic mutation in Drosophila melanogaster: The causal relationship of bristle number to fitness

Genetics, 139(2), 861.

By: S. Nuzhdin, J. Fry & T. Mackay

Source: NC State University Libraries
Added: August 6, 2018

1995 journal article

THE DISTRIBUTION OF TRANSPOSABLE ELEMENTS ON X-CHROMOSOMES FROM A NATURAL-POPULATION OF DROSOPHILA-SIMULANS

GENETICAL RESEARCH, 66(2), 159–166.

By: S. Nuzhdin n

MeSH headings : Africa; Animals; DNA Transposable Elements / genetics; Drosophila / genetics; Drosophila melanogaster / genetics; Female; Gene Dosage; In Situ Hybridization; X Chromosome
TL;DR: Data provide evidence for the operation of a force (or forces) opposing transpositional increase in copy number, and that this force is weaker at the bases of chromosomes, consistent with the idea that recombination between elements at non-homologous sites contains TE copy number. (via Semantic Scholar)
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UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

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