Paul E. Hoyle

Works (2)

Updated: July 5th, 2023 16:01

2001 article

Transforming Growth Factor-β1 Modifies Fibroblast Growth Factor-2 Production in Type II Cells

Li, C.-M., Khosla, J., Hoyle, P., & Sannes, P. L. (2001, July 1). CHEST Journal.

By: C. Li n, J. Khosla n, P. Hoyle n & P. Sannes n

author keywords: alveolar epithelium; extracellular matrix; growth factors
MeSH headings : Animals; Fibroblast Growth Factor 2 / biosynthesis; Pulmonary Alveoli / metabolism; Rats; Rats, Inbred F344; Transforming Growth Factor beta / physiology; Transforming Growth Factor beta1
topics (OpenAlex): Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis; Fibroblast Growth Factor Research; Neonatal Respiratory Health Research
TL;DR: Important regulatory links between FGF-2, sulfated ECMs, and both TGF-β 1 and FGF, which could contribute to the modulation of normal cell turnover, development, and repair processes attendant to fibrosis in the lung are demonstrated. (via Semantic Scholar)
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2000 article

TGF-β1 and fibroblast growth factor-1 modify fibroblast growth factor-2 production in type II cells

Li, C.-M., Khosla, J., Pagan, I., Hoyle, P., & Sannes, P. L. (2000, December 1). American Journal of Physiology-Lung Cellular and Molecular Physiology.

By: C. Li n, J. Khosla n, I. Pagan n, P. Hoyle n & P. Sannes n

author keywords: basic fibroblast growth factor; acidic fibroblast growth factor; alveolar epithelium; alveolar injury; pulmonary fibrosis; transforming growth factor
MeSH headings : Animals; Cells, Cultured; Dose-Response Relationship, Drug; Fibroblast Growth Factor 1; Fibroblast Growth Factor 2 / genetics; Fibroblast Growth Factor 2 / pharmacology; Gene Expression / drug effects; Pulmonary Alveoli / cytology; Pulmonary Alveoli / metabolism; Pulmonary Fibrosis / metabolism; RNA, Messenger / analysis; Rats; Rats, Inbred F344; Receptor Protein-Tyrosine Kinases / genetics; Receptor, Fibroblast Growth Factor, Type 1; Receptors, Fibroblast Growth Factor / genetics; Specific Pathogen-Free Organisms; Transforming Growth Factor beta / pharmacology
topics (OpenAlex): Fibroblast Growth Factor Research; Neonatal Respiratory Health Research; Proteoglycans and glycosaminoglycans research
TL;DR: Fibroblast growth factor (FGF)-2, which stimulates DNA synthesis by type II cells in the lung, has been shown to be regulated by transforming growth factors (TGF)-β1, an important inflammatory cytokine. (via Semantic Scholar)
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

Citation Index includes data from a number of different sources. If you have questions about the sources of data in the Citation Index or need a set of data which is free to re-distribute, please contact us.

Certain data included herein are derived from the Web of Science© and InCites© (2026) of Clarivate Analytics. All rights reserved. You may not copy or re-distribute this material in whole or in part without the prior written consent of Clarivate Analytics.