William Michael Russell

Works (10)

Updated: July 5th, 2023 16:00

2009 patent

Lactobacillus acidophillus nucleic acid sequences encoding cell surface protein homologues and uses therefore

By: T. Klaenhammer, W. Russell, E. Altermann & B. Buck

Source: NC State University Libraries
Added: August 6, 2018

2009 patent

Lactobacillus acidophilus nucleic acid sequences encoding stress-related proteins and uses therefor

By: T. Klaenhammer, E. Altermann, M. Azcarate-Peril, O. McAuliffe & W. Russell

Source: NC State University Libraries
Added: August 6, 2018

2009 patent

Nucleic acid sequences encoding two-component sensing and regulatory proteins, antimicrobial proteins and uses therefor

By: T. Klaenhammer, W. Russell, E. Altermann & A. Azcarate-Peril

Source: NC State University Libraries
Added: August 6, 2018

2008 patent

Lactobacillus acidophilus nucleic acid sequences encoding carbohydrate utilization-related proteins and uses therefor

Source: NC State University Libraries
Added: August 6, 2018

2008 patent

Lactobacillus acidophilus nucleic acid sequences encoding protease homologues and uses therefore

By: T. Klaenhammer, E. Altermann & W. Russell

Source: NC State University Libraries
Added: August 6, 2018

2006 journal article

Modification of Lactobacillus beta-glucuronidase activity by random mutagenesis

GENE, 389(2), 122–127.

By: M. Callanan n, W. Russell n & T. Klaenhammer n

author keywords: Lactobacillus gasseri gusA; gene; reporter enzyme; pH range; Epicurian coli
MeSH headings : Amino Acid Sequence; Amino Acid Substitution; Bacterial Proteins / chemistry; Bacterial Proteins / genetics; Bacterial Proteins / metabolism; Cloning, Molecular; DNA, Bacterial; Escherichia coli / enzymology; Escherichia coli / genetics; Genes, Bacterial; Glucuronidase / chemistry; Glucuronidase / genetics; Glucuronidase / metabolism; Hydrogen-Ion Concentration; Lactobacillus / enzymology; Lactobacillus / genetics; Molecular Sequence Data; Mutagenesis; Sequence Alignment; Sequence Analysis, DNA; Transformation, Bacterial
TL;DR: The modified GusA3 enzyme has expanded potential for use as a reporter enzyme in expression hosts that are not acidophilic, as well as lactic acid bacteria and other microorganisms that grow in acidifying environments. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2005 journal article

Complete genome sequence of the probiotic lactic acid bacterium Lactobacillus acidophilus NCFM

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 102(11), 3906–3912.

By: E. Altermann n, W. Russell n, M. Azcarate-Peril n, R. Barrangou n, B. Buck n, O. McAuliffe n, N. Souther n, A. Dobson n ...

author keywords: adhesion; stress response; proteolytic system; sugar metabolism; in silico analysis
MeSH headings : Bacterial Adhesion / genetics; Bacteriocins / genetics; Bacteriophages / genetics; Bacteriophages / pathogenicity; Carbohydrate Metabolism; Computational Biology; Genome, Bacterial; Lactobacillus acidophilus / genetics; Lactobacillus acidophilus / metabolism; Lactobacillus acidophilus / virology; Molecular Sequence Data; Peptide Hydrolases / genetics; Prophages / genetics; Sequence Analysis, DNA; Transposases / genetics
TL;DR: These features within the genome sequence of L. acidophilus are likely to contribute to the organisms' gastric survival and promote interactions with the intestinal mucosa and microbiota. (via Semantic Scholar)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2005 journal article

Microarray analysis of a two-component regulatory system involved in acid resistance and proteolytic activity in Lactobacillus acidophilus

APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 71(10), 5794–5804.

MeSH headings : Bacterial Proteins / genetics; Bacterial Proteins / metabolism; Base Sequence; Culture Media; Gene Expression Profiling; Gene Expression Regulation, Bacterial; Histidine Kinase; Hydrogen-Ion Concentration; Lactobacillus acidophilus / genetics; Lactobacillus acidophilus / growth & development; Lactobacillus acidophilus / metabolism; Lactobacillus acidophilus / physiology; Mutation; Oligonucleotide Array Sequence Analysis / methods; Peptide Hydrolases / genetics; Peptide Hydrolases / metabolism; Protein Kinases / genetics; Protein Kinases / metabolism; Signal Transduction
Source: Web Of Science
Added: August 6, 2018

2003 patent

Polynucleotide encoding a Lactobacillus gasseri beta-glucuronidase polypeptide

Washington, DC: U.S. Patent and Trademark Office.

By: W. Russell & T. Klaenhammer

Source: NC State University Libraries
Added: August 6, 2018

2001 journal article

Efficient system for directed integration into the Lactobacillus acidophilus and Lactobacillus gasseri chromosomes via homologous recombination

APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 67(9), 4361–4364.

By: W. Russell* & T. Klaenhammer n

MeSH headings : Biotechnology / methods; Chromosomes, Bacterial / genetics; Genetic Vectors; Glucuronidase / genetics; Lactobacillus / genetics; Lactobacillus acidophilus / genetics; Plasmids / genetics; Recombination, Genetic / genetics; beta-Galactosidase / genetics
TL;DR: An efficient method is described for the generation of site-specific chromosomal integrations in Lactobacillus acidophilus and LactOBacillus gasseri using the lactococcal pORI system and relies on the simultaneous use of two plasmids. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

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