Todd Matthew Skeen

Works (7)

Updated: July 5th, 2023 16:00

2003 journal article

A model of mucopolysaccharidosis IIIB (Sanfilippo syndrome type IIIB): N-acetyl-alpha-D-glucosaminidase deficiency in Schipperke dogs

JOURNAL OF INHERITED METABOLIC DISEASE, 26(5), 489–504.

By: N. Ellinwood *, P. Wang*, T. Skeen n, N. Sharp *, M. Cesta n, S. Decker n, N. Edwards *, I. Bublot n ...

MeSH headings : Acetylglucosaminidase / deficiency; Animals; Disease Models, Animal; Dog Diseases / genetics; Dog Diseases / metabolism; Dog Diseases / pathology; Dogs; Female; Glycosaminoglycans / urine; Male; Mucopolysaccharidosis III / genetics; Mucopolysaccharidosis III / metabolism; Mucopolysaccharidosis III / pathology
TL;DR: Dogs with naturally occurring MPS IIIB are reported on, detailing the clinical signs, diagnosis, histopathology, tissue enzymology and substrate levels, and an obligate heterozygote has been established to aid in understanding the pathogenesis of MPSIIIB and testing of potential therapies. (via Semantic Scholar)
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Source: Web Of Science
Added: August 6, 2018

2003 journal article

Long-term functional outcome of dogs with severe injuries of the thoracolumbar spinal cord: 87 cases (1996–2001)

Journal of the American Veterinary Medical Association, 222(6), 762–769.

By: N. Olby n , J. Levine n , T. Harris*, K. Muñana n , T. Skeen n & N. Sharp n

Contributors: N. Olby n , J. Levine n , T. Harris*, K. Muñana n , T. Skeen n & N. Sharp n

MeSH headings : Age Factors; Animals; Body Weight; Dog Diseases / physiopathology; Dog Diseases / surgery; Dogs; Female; Intervertebral Disc Displacement / physiopathology; Intervertebral Disc Displacement / surgery; Intervertebral Disc Displacement / veterinary; Laminectomy / veterinary; Lumbar Vertebrae; Male; Pain / veterinary; Paraplegia / etiology; Paraplegia / surgery; Paraplegia / veterinary; Prognosis; Recovery of Function; Retrospective Studies; Spinal Cord Injuries / physiopathology; Spinal Cord Injuries / surgery; Spinal Cord Injuries / veterinary; Thoracic Vertebrae; Treatment Outcome
TL;DR: Results suggested that the prognosis for paraplegic dogs without DPP because of trauma was guarded, while dogs with disk herniation had a better chance of recovering motor function. (via Semantic Scholar)
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Sources: Web Of Science, ORCID, NC State University Libraries, Crossref
Added: August 6, 2018

2003 journal article

Spinal arachnoid cysts in 17 dogs

JOURNAL OF THE AMERICAN ANIMAL HOSPITAL ASSOCIATION, 39(3), 271–282.

By: T. Skeen n, N. Olby n , K. Munana n  & N. Sharp n

Contributors: T. Skeen n, N. Olby n , K. Muñana n  & N. Sharp n

MeSH headings : Animals; Arachnoid Cysts / epidemiology; Arachnoid Cysts / veterinary; Cervical Vertebrae; Dog Diseases / diagnostic imaging; Dog Diseases / epidemiology; Dog Diseases / etiology; Dog Diseases / pathology; Dog Diseases / surgery; Dogs; Female; Magnetic Resonance Imaging / veterinary; Male; Myelography / veterinary; North Carolina / epidemiology; Records / veterinary; Retrospective Studies; Spinal Diseases / epidemiology; Spinal Diseases / veterinary; Spinal Fusion / veterinary; Thoracic Vertebrae
TL;DR: The medical records of 17 dogs diagnosed with spinal arachnoid cysts at North Carolina State University Veterinary Teaching Hospital were retrospectively examined to identify trends in signalment, history, neurological status, treatment, and short- and long-term prognosis. (via Semantic Scholar)
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Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2002 article

Use of vagal nerve stimulation as a treatment for refractory epilepsy in dogs

Munana, K. R., Vitek, S. M., Tarver, W. B., Saito, M., Skeen, T. M., Sharp, N. J. H., … Haglund, M. M. (2002, October 1). JOURNAL OF THE AMERICAN VETERINARY MEDICAL ASSOCIATION, Vol. 221, pp. 977–983.

By: K. Munana n , S. Vitek n, W. Tarver n, M. Saito n, T. Skeen n, N. Sharp  n, N. Olby n , M. Haglund  n

Contributors: K. Muñana n , S. Vitek n, W. Tarver n, M. Saito n, T. Skeen n, N. Sharp  n, N. Olby n , M. Haglund  n

MeSH headings : Animals; Cross-Over Studies; Dog Diseases / therapy; Dogs; Electric Stimulation Therapy / adverse effects; Electric Stimulation Therapy / methods; Electric Stimulation Therapy / veterinary; Epilepsy / therapy; Epilepsy / veterinary; Female; Male; Pacemaker, Artificial / veterinary; Safety; Seizures / prevention & control; Seizures / veterinary; Treatment Outcome; Vagus Nerve / physiopathology
TL;DR: Vagal nerve stimulation is a potentially safe approach to seizure control that appears to be efficacious in certain dogs and should be considered a possible treatment option when antiepileptic medications are ineffective. (via Semantic Scholar)
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Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2001 journal article

Characterization of a canine model of mucopolysaccharidosis IIIB.

American Journal of Human Genetics, 69(4), 1760.

By: N. Ellinwood, P. Wang, T. Skeen, N. Sharp, M. Cesta, W. Bush, E. Hardam, M. Haskins, U. Giger

Source: NC State University Libraries
Added: August 6, 2018

2001 journal article

Development of a functional scoring system in dogs with acute spinal cord injuries

AMERICAN JOURNAL OF VETERINARY RESEARCH, 62(10), 1624–1628.

By: N. Olby n , L. De Risio  n, K. Munana n , M. Wosar n, T. Skeen n, N. Sharp n, B. Keene n

Contributors: N. Olby n , L. De Risio  n, K. Muñana n , M. Wosar n, T. Skeen n, N. Sharp n, B. Keene n

MeSH headings : Animals; Dog Diseases / physiopathology; Dogs; Gait / physiology; Hindlimb / physiopathology; Intervertebral Disc Displacement / physiopathology; Intervertebral Disc Displacement / veterinary; Observer Variation; Paraplegia / etiology; Paraplegia / veterinary; Reproducibility of Results; Severity of Illness Index; Spinal Cord Diseases / complications; Spinal Cord Diseases / physiopathology; Spinal Cord Diseases / veterinary; Statistics, Nonparametric; Videotape Recording
TL;DR: Pelvic limb gait of dogs recovering from thoracolumbar spinal cord injuries can be reliably quantified, using a numeric scale, and this scale will facilitate the performance of clinical trials aimed at improving the outcome of acute spinal Cord injuries. (via Semantic Scholar)
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3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2001 journal article

Intervertebral disk disease in 10 cats

JOURNAL OF THE AMERICAN ANIMAL HOSPITAL ASSOCIATION, 37(4), 384–389.

By: K. Munana n , N. Olby* , N. Sharp & T. Skeen*

Contributors: K. Muñana n , N. Olby* , N. Sharp & T. Skeen*

MeSH headings : Animals; Cat Diseases / diagnostic imaging; Cat Diseases / epidemiology; Cat Diseases / pathology; Cats; Female; Intervertebral Disc; Lumbar Vertebrae; Male; North Carolina / epidemiology; Radiography; Records / veterinary; Retrospective Studies; Spinal Diseases / diagnostic imaging; Spinal Diseases / epidemiology; Spinal Diseases / pathology; Spinal Diseases / veterinary
TL;DR: The medical records of 10 cats diagnosed with intervertebral disk disease were reviewed, and all cats judged to have an excellent outcome had undergone surgical decompression. (via Semantic Scholar)
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

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