Carla Mattos

Exploring the Rap1A Active Site Through Accelerated Molecular Dynamic Simulations

Schwabe, M., Holzapfel, G., & Mattos, C. (2020, April 1). The FASEB Journal.

DRoP: Automated detection of conserved solvent‐binding sites on proteins

Kearney, B. M., Schwabe, M., Marcus, K. C., Roberts, D. M., Dechene, M., Swartz, P., & Mattos, C. (2019, July 11). Proteins Structure Function and Bioinformatics.

Titration of ionizable groups in proteins using multiple neutron data sets from a single crystal: application to the small GTPase Ras

Knihtila, R., Volmar, A. Y., Meilleur, F., & Mattos, C. (2019, January 23). Acta Crystallographica Section F Structural Biology Communications, Vol. 75, pp. 111–115.

Neutron scattering in the biological sciences: progress and prospects

Ashkar, R., Bilheux, H. Z., Bordallo, H., Briber, R., Callaway, D. J. E., Cheng, X., … Smith, J. C. (2018, December 1). Acta Crystallographica Section D Structural Biology, Vol. 74, pp. 1129–1168.

Allosteric Effects of the Oncogenic RasQ61L Mutant on Raf-RBD

Fetics, S. K., Guterres, H., Kearney, B. M., Buhrman, G., Ma, B., Nussinov, R., & Mattos, C. (2015, February 12). Structure.

Neutron Crystal Structure of RAS GTPase Puts in Question the Protonation State of the GTP γ-Phosphate

Knihtila, R., Holzapfel, G., Weiss, K., Meilleur, F., & Mattos, C. (2015, October 29). Journal of Biological Chemistry, Vol. 290, pp. 31025–31036.

DRoP: A Water Analysis Program Identifies Ras-GTP-Specific Pathway of Communication between Membrane-Interacting Regions and the Active Site

Kearney, B. M., Johnson, C. W., Roberts, D. M., Swartz, P., & Mattos, C. (2013, November 2). Journal of Molecular Biology.

Allosteric modulation of caspase 3 through mutagenesis

Walters, J., Schipper, J. L., Swartz, P., Mattos, C., & Clark, A. C. (2012, May 21). Bioscience Reports.

Shift in the Equilibrium between On and Off States of the Allosteric Switch in Ras-GppNHp Affected by Small Molecules and Bulk Solvent Composition

Holzapfel, G., Buhrman, G., & Mattos, C. (2012, July 30). Biochemistry.

Structurally Conserved Nop56/58 N-terminal Domain Facilitates Archaeal Box C/D Ribonucleoprotein-guided Methyltransferase Activity

Gagnon, K. T., Biswas, S., Zhang, X., Brown, B. A., Wollenzien, P., Mattos, C., & Maxwell, E. S. (2012, April 12). Journal of Biological Chemistry.

Comparative Analysis of the 15.5kD Box C/D snoRNP Core Protein in the Primitive Eukaryote Giardia lamblia Reveals Unique Structural and Functional Features

Biswas, S., Buhrman, G., Gagnon, K., Mattos, C., Brown, B. A., & Maxwell, E. S. (2011, March 2). Biochemistry.

Thermodynamic, enzymatic and structural effects of removing a salt bridge at the base of loop 4 in (pro)caspase-3

Walters, J., Swartz, P., Mattos, C., & Clark, A. C. (2011, January 24). Archives of Biochemistry and Biophysics.

Allosteric Modulation of Ras-GTP Is Linked to Signal Transduction through RAF Kinase

Buhrman, G., Kumar, V. S. S., Cirit, M., Haugh, J. M., & Mattos, C. (2010, November 23). Journal of Biological Chemistry, Vol. 286, pp. 3323–3331.

Allosteric modulation of Ras positions Q61 for a direct role in catalysis

Buhrman, G., Holzapfel, G., Fetics, S., & Mattos, C. (2010, March 1). Proceedings of the National Academy of Sciences.

A constitutively active and uninhibitable caspase-3 zymogen efficiently induces apoptosis

Walters, J., Pop, C., Scott, F. L., Drag, M., Swartz, P., Mattos, C., … Clark, A. C. (2009, October 1). Biochemical Journal.

Fragment-based identification of druggable ‘hot spots’ of proteins using Fourier domain correlation techniques

Brenke, R., Kozakov, D., Chuang, G.-Y., Beglov, D., Hall, D., Landon, M. R., … Vajda, S. (2009, January 28). Bioinformatics.

Multiple solvent crystal structures of ribonuclease A: An assessment of the method

Dechene, M., Wink, G., Smith, M., Swartz, P., & Mattos, C. (2009, February 2). Proteins Structure Function and Bioinformatics.

Minimizing frustration by folding in an aqueous environment

[Review of ]. Archives of Biochemistry and Biophysics, 469(1), 118–131.

Rapid Folding and Unfolding of Apaf-1 CARD

Milam, S. L., Nicely, N. I., Feeney, B., Mattos, C., & Clark, A. C. (2007, March 16). Journal of Molecular Biology.

Transformation Efficiency of RasQ61 Mutants Linked to Structural Features of the Switch Regions in the Presence of Raf

Buhrman, G., Wink, G., & Mattos, C. (2007, December 1). Structure.

Multiple Solvent Crystal Structures: Probing Binding Sites, Plasticity and Hydration

Mattos, C., Bellamacina, C. R., Peisach, E., Pereira, A., Vitkup, D., Petsko, G. A., & Ringe, D. (2006, January 31). Journal of Molecular Biology.

Role of Loop Bundle Hydrogen Bonds in the Maturation and Activity of (Pro)caspase-3

Feeney, B., Pop, C., Swartz, P., Mattos, C., & Clark, A. C. (2006, October 17). Biochemistry.

Structural Mechanism of Oxidative Regulation of the Phosphatase Cdc25B via an Intramolecular Disulfide Bond^,

Buhrman, G., Parker, B., Sohn, J., Rudolph, J., & Mattos, C. (2005, March 17). Biochemistry.

Crystal Structures of Ral-GppNHp and Ral-GDP Reveal Two Binding Sites that Are Also Present in Ras and Rap

Nicely, N. I., Kosak, J., Serrano, V., & Mattos, C. (2004, November 1). Structure.

X‐ray structural and simulation analysis of a protein mutant: The value of a combined approach

Mattos, C., Cohen, J. D., Green, D. F., Tidor, B., & Karplus, M. (2004, March 5). Proteins Structure Function and Bioinformatics.

Organic Solvents Order the Dynamic Switch II in Ras Crystals

Buhrman, G., Serrano, V., & Mattos, C. (2003, July 1). Structure.

Protein-water interactions in a dynamic world

[Review of ]. Trends in Biochemical Sciences, 27(4), 203–208.

Proteins in organic solvents

Mattos, C. (2001, December 1). Current Opinion in Structural Biology.