Thomas W. Vahlenkamp

Works (16)

Updated: July 5th, 2023 16:00
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2014 journal article

Antiviral efficacy of nine nucleoside reverse transcriptase inhibitors against feline immunodeficiency virus in feline peripheral blood mononuclear cells

AMERICAN JOURNAL OF VETERINARY RESEARCH, 75(3), 273–281.

By: A. Schwartz*, M. McCrackin, R. Schinazi, P. Hill, T. Vahlenkamp*, M. Tompkins*, K. Hartmann

co-author countries: United States of America 🇺🇸
MeSH headings : Animals; Antiviral Agents / pharmacology; Cats; Cell Line; Immunodeficiency Virus, Feline / drug effects; Leukocytes, Mononuclear / drug effects; Leukocytes, Mononuclear / virology; Reverse Transcriptase Inhibitors / pharmacology
Source: Web Of Science
Added: August 6, 2018

2006 journal article

Cerebrospinal fluid is an efficient route for establishing brain infection with feline immunodeficiency virus and transfering infectious virus to the periphery

JOURNAL OF NEUROVIROLOGY, 12(4), 294–306.

By: P. Liu n, L. Hudson n, M. Tompkins n, T. Vahlenkamp n, B. Colby n, C. Rundle*, R. Meeker*

co-author countries: Germany 🇩🇪 United States of America 🇺🇸
author keywords: dementia; HIV; macrophages; T cells; viremia
MeSH headings : Animals; Brain Diseases / cerebrospinal fluid; Brain Diseases / immunology; Brain Diseases / virology; Cats; DNA, Viral / isolation & purification; Feline Acquired Immunodeficiency Syndrome / cerebrospinal fluid; Feline Acquired Immunodeficiency Syndrome / immunology; Feline Acquired Immunodeficiency Syndrome / virology; Immunodeficiency Virus, Feline / genetics; Immunodeficiency Virus, Feline / isolation & purification; Lymphocyte Subsets / immunology; Macrophages / immunology; Macrophages / virology; RNA, Viral / blood; RNA, Viral / cerebrospinal fluid; Viral Load
Source: Web Of Science
Added: August 6, 2018

2006 journal article

Compartmentalization and evolution of feline immunodeficiency virus between the central nervous system and periphery following intracerebroventricular or systemic inoculation

JOURNAL OF NEUROVIROLOGY, 12(4), 307–321.

By: P. Liu n, L. Hudson n, M. Tompkins n, T. Vahlenkamp n & R. Meeker*

co-author countries: Germany 🇩🇪 United States of America 🇺🇸
author keywords: brain; cerebrospinal fluid; dementia; evolution; heteroduplex tracking assay; HIV
MeSH headings : Animals; Brain / virology; Cats; Central Nervous System Diseases / blood; Central Nervous System Diseases / cerebrospinal fluid; Central Nervous System Diseases / virology; Feline Acquired Immunodeficiency Syndrome / blood; Feline Acquired Immunodeficiency Syndrome / cerebrospinal fluid; Feline Acquired Immunodeficiency Syndrome / virology; Genes, env; Heteroduplex Analysis; Immunodeficiency Virus, Feline / genetics; Immunodeficiency Virus, Feline / metabolism; Leukocytes, Mononuclear / virology; Peripheral Nervous System Diseases / blood; Peripheral Nervous System Diseases / cerebrospinal fluid; Peripheral Nervous System Diseases / virology; RNA, Viral / blood; RNA, Viral / cerebrospinal fluid
Source: Web Of Science
Added: August 6, 2018

2005 article

The role of CD4(+)CD25(+) regulatory T cells in viral infections

Vahlenkamp, T. W., Tompkins, M. B., & Tompkins, W. A. F. (2005, October 18). VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY, Vol. 108, pp. 219–225.

By: T. Vahlenkamp*, M. Tompkins n & W. Tompkins n

co-author countries: Germany 🇩🇪 United States of America 🇺🇸
author keywords: regulatory T cells; viral infection; immune regulation; immunosuppression
MeSH headings : Animals; CD4-Positive T-Lymphocytes / immunology; Herpesviridae Infections / immunology; Immune Tolerance; Lymphocyte Activation; Mice; Picornaviridae Infections / immunology; Receptors, Interleukin-2 / metabolism; Retroviridae Infections / immunology; T-Lymphocyte Subsets / immunology; Virus Diseases / immunology
Source: Web Of Science
Added: August 6, 2018

2004 journal article

B7(+)CTLA4(+) T cells engage in T-T cell interactions that mediate apoptosis: a model for lentivirus-induced T cell depletion

VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY, 98(3-4), 203–214.

By: T. Vahlenkamp n, M. Bull n, J. Dow n, E. Collisson*, B. Winslow, A. Phadke*, W. Tompkins n, M. Tompkins n

co-author countries: United States of America 🇺🇸
author keywords: FIV; apoptosis; 137 costimulatory molecules; CTLA4
MeSH headings : Animals; Antigens, CD / biosynthesis; Antigens, CD / immunology; Antigens, Differentiation / biosynthesis; Antigens, Differentiation / immunology; Apoptosis / immunology; B7-1 Antigen / biosynthesis; B7-1 Antigen / immunology; B7-2 Antigen; CTLA-4 Antigen; Cats; Cell Communication / immunology; Concanavalin A / immunology; Feline Acquired Immunodeficiency Syndrome / immunology; Flow Cytometry / veterinary; Immunodeficiency Virus, Feline / immunology; In Situ Nick-End Labeling / veterinary; Ionomycin / immunology; Lymphocyte Activation / immunology; Membrane Glycoproteins / biosynthesis; Membrane Glycoproteins / immunology; Specific Pathogen-Free Organisms; T-Lymphocytes / immunology; T-Lymphocytes / virology; Tetradecanoylphorbol Acetate / immunology
Source: Web Of Science
Added: August 6, 2018

2004 journal article

Combined anti-retroviral therapy (CART) in a feline immunodeficiency virus (FIV)infected cat

Kleintier-Praxis, 49(8), 517-.

By: J. Huebner, D. Klein, E. Muller, T. Vahlenkamp & I. Langbein

Source: NC State University Libraries
Added: August 6, 2018

2004 journal article

Feline immunodeficiency virus infection phenotypically and functionally activates immunosuppressive CD4(+)CD25(+) T regulatory cells

JOURNAL OF IMMUNOLOGY, 172(8), 4752–4761.

By: T. Vahlenkamp n, M. Tompkins n & W. Tompkins n

co-author countries: United States of America 🇺🇸
MeSH headings : Animals; Antigens, CD / biosynthesis; Antigens, CD / metabolism; Antigens, Differentiation / biosynthesis; Antigens, Viral / biosynthesis; B7-1 Antigen / biosynthesis; B7-1 Antigen / metabolism; B7-2 Antigen; CTLA-4 Antigen; Cats; Cell Division / immunology; Cell Separation; Cells, Cultured; Chronic Disease; Coculture Techniques; Concanavalin A / pharmacology; Feline Acquired Immunodeficiency Syndrome / immunology; Feline Acquired Immunodeficiency Syndrome / virology; Immune Tolerance; Immunodeficiency Virus, Feline / immunology; Immunophenotyping; Interleukin-2 / biosynthesis; Interleukin-2 / deficiency; Ligands; Lipopolysaccharides / pharmacology; Lymph Nodes / cytology; Lymph Nodes / immunology; Lymphocyte Activation / immunology; Lymphocyte Count; Membrane Glycoproteins / biosynthesis; Membrane Glycoproteins / metabolism; Receptors, Interleukin-2 / biosynthesis; Receptors, Interleukin-2 / blood; Receptors, Interleukin-2 / metabolism; T-Lymphocyte Subsets / immunology; T-Lymphocyte Subsets / metabolism; T-Lymphocyte Subsets / virology; T-Lymphocytes, Regulatory / immunology; T-Lymphocytes, Regulatory / metabolism; T-Lymphocytes, Regulatory / virology; Up-Regulation / immunology
Source: Web Of Science
Added: August 6, 2018

2004 journal article

Preferential replication of FIV in activated CD4(+)CD25(+)T cells independent of cellular proliferation

VIROLOGY, 321(2), 307–322.

By: A. Joshi n, T. Vahlenkamp n, H. Garg n, W. Tompkins n & M. Tompkins n

co-author countries: United States of America 🇺🇸
author keywords: FIV; HIV; AIDS; latency; stimulation; anergy; apoptosis; reservoir
MeSH headings : Animals; Apoptosis; CD4-Positive T-Lymphocytes / immunology; CD4-Positive T-Lymphocytes / virology; Cats; Cell Division / immunology; Disease Models, Animal; Feline Acquired Immunodeficiency Syndrome / immunology; Feline Acquired Immunodeficiency Syndrome / virology; Immunodeficiency Virus, Feline / physiology; Lymphocyte Activation; Receptors, Interleukin-2 / analysis; Virus Latency; Virus Replication
Source: Web Of Science
Added: August 6, 2018

2004 journal article

Spontaneous T cell apoptosis in feline immunodeficiency virus (FIV)-infected cats is inhibited by IL2 and anti-B7.1 antibodies

VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY, 99(1-2), 25–37.

By: M. Bull n, T. Vahlenkamp n, J. Dow n, E. Collisson*, B. Winslow, A. Phadke*, M. Tompkins n, W. Tompkins n

co-author countries: United States of America 🇺🇸
author keywords: FIV; apoptosis; IL2; B7 co-stimulatory molecules; CTLA4
MeSH headings : Animals; Antibodies, Blocking / immunology; Antigens, CD / immunology; Apoptosis / drug effects; Apoptosis / immunology; B7-2 Antigen; CD4-Positive T-Lymphocytes / immunology; CD4-Positive T-Lymphocytes / pathology; CD4-Positive T-Lymphocytes / virology; CD8-Positive T-Lymphocytes / immunology; CD8-Positive T-Lymphocytes / pathology; CD8-Positive T-Lymphocytes / virology; Cats; Feline Acquired Immunodeficiency Syndrome / blood; Feline Acquired Immunodeficiency Syndrome / immunology; Immunodeficiency Virus, Feline / genetics; Immunodeficiency Virus, Feline / immunology; In Situ Nick-End Labeling / veterinary; Interleukin-2 / immunology; Interleukin-2 / pharmacology; Lymph Nodes / immunology; Lymphocyte Activation / immunology; Membrane Glycoproteins / antagonists & inhibitors; Membrane Glycoproteins / immunology; RNA, Viral / chemistry; RNA, Viral / genetics; Reverse Transcriptase Polymerase Chain Reaction / veterinary; Specific Pathogen-Free Organisms
Source: Web Of Science
Added: August 6, 2018

2003 journal article

Generation of reference values for the characterization of lymphocyte subpopulations in the peripheral blood of dogs and cats

Kleintier-Praxis, 48(9), 537-.

By: I. Langbein, P. Kuhnlein, C. Schimmer, T. Vahlenkamp, J. Huebner & E. Muller

Source: NC State University Libraries
Added: August 6, 2018

2002 journal article

Cerebrospinal fluid centesis at the cerebellomedullary cistern of kittens

Contemporary Topics in Laboratory Animal Science, 41(5), 30–32.

By: L. Hudson, T. Vahlenkamp, K. Howard, B. Colby, M. Tompkins & R. Meeker

Source: NC State University Libraries
Added: August 6, 2018

2002 article

Feline immunodeficiency virus infection is characterized by B7(+)CTLA4(+) T cell apoptosis

Tompkins, M. B., Bull, M. E., Dow, J. L., Ball, J. M., Collisson, E. W., Winslow, B. J., … Tompkins, W. A. (2002, April 15). JOURNAL OF INFECTIOUS DISEASES, Vol. 185, pp. 1077–1093.

By: M. Tompkins*, M. Bull*, J. Dow*, J. Ball, E. Collisson, B. Winslow, A. Phadke, T. Vahlenkamp*, W. Tompkins*

MeSH headings : Abatacept; Animals; Antigens, CD / analysis; Antigens, Differentiation / analysis; Apoptosis; B7-1 Antigen / analysis; B7-2 Antigen; CTLA-4 Antigen; Cats; Feline Acquired Immunodeficiency Syndrome / immunology; Immunoconjugates; In Situ Nick-End Labeling; Membrane Glycoproteins / analysis; T-Lymphocytes / physiology
Source: Web Of Science
Added: August 6, 2018

2002 journal article

Persistence of Borna disease virus in naturally infected sheep

JOURNAL OF VIROLOGY, 76(19), 9735–9743.

By: T. Vahlenkamp*, A. Konrath *, M. Weber * & H. Muller*

co-author countries: Germany 🇩🇪 Slovakia 🇸🇰
MeSH headings : Animals; Antibodies, Viral / analysis; Borna Disease / virology; Borna disease virus / immunology; Borna disease virus / isolation & purification; Glycoproteins / chemistry; Glycoproteins / genetics; Immunohistochemistry; In Situ Hybridization; Male; RNA, Viral / analysis; Reverse Transcriptase Polymerase Chain Reaction; Sheep; Sheep Diseases / virology; Viral Proteins / chemistry; Viral Proteins / genetics
Source: Web Of Science
Added: August 6, 2018

2001 conference paper

B7.1/B7.2 and CTLA4 expression on feline T cells in vitro correlates with apoptosis

Journal of Leukocyte Biology, (2001), 255.

By: T. Vahlenkamp, M. Bull, J. Dow, J. Anderson, M. Tompkins & W. Tompkins

Source: NC State University Libraries
Added: August 6, 2018

2001 journal article

Changes of the organotypic retinal organization in Borna virus-infected Lewis rats

JOURNAL OF NEUROCYTOLOGY, 30(9-10), 801–820.

By: J. Kacza, C. Mohr, T. Pannicke, H. Kuhrt, J. Dietzel, M. Fluss, J. Richt, T. Vahlenkamp* ...

MeSH headings : Animals; Antigens, Viral / metabolism; Borna Disease / pathology; Borna Disease / physiopathology; Borna disease virus / metabolism; Borna disease virus / pathogenicity; Disease Models, Animal; Glial Fibrillary Acidic Protein / metabolism; Immunohistochemistry; Membrane Potentials / physiology; Microglia / pathology; Microglia / ultrastructure; Microglia / virology; Microscopy, Electron; Organ Culture Techniques; Photoreceptor Cells / pathology; Photoreceptor Cells / ultrastructure; Photoreceptor Cells / virology; Rats; Rats, Inbred Lew; Retina / pathology; Retina / ultrastructure; Retina / virology; Retinal Diseases / pathology; Retinal Diseases / physiopathology; Retinal Diseases / virology; Retinal Ganglion Cells / pathology; Retinal Ganglion Cells / ultrastructure; Retinal Ganglion Cells / virology
Source: Web Of Science
Added: August 6, 2018

2001 conference paper

T cell apoptosis in FIV-infected cats is blocked by the addition of antibodies to B7.1 and B7.2

Journal of Leukocyte Biology, (2001), 256.

By: M. Bull, T. Vahlenkamp, M. Tompkins & W. Tompkins

Source: NC State University Libraries
Added: August 6, 2018