Piotr Mucha

Works (3)

Updated: July 5th, 2023 16:00

2004 article

Sequence-Altered Peptide Adopts Optimum Conformation for Modification-Dependent Binding of the Yeast tRNAPhe Anticodon Domain

Mucha, P., Szyk, A., Rekowski, P., & Agris, P. F. (2004, January 1). The Protein Journal.

By: P. Mucha*, A. Szyk, P. Rekowski & P. Agris*

author keywords: beta-turn; methylated nucleosides; phage display library; RNA-peptide interaction
MeSH headings : Anticodon / chemistry; Circular Dichroism; Molecular Conformation; Oligoribonucleotides / chemistry; Peptide Library; Peptides / chemistry; RNA, Fungal / chemistry; RNA, Transfer, Phe / chemistry; Saccharomyces cerevisiae / chemistry
topics (OpenAlex): RNA and protein synthesis mechanisms; RNA Research and Splicing; RNA modifications and cancer
TL;DR: The results suggest that peptides with different conformations, but similar affinities, adopt the optimal binding conformation, indicative of a structurally adaptive model of binding in which the modified RNA serves as a scaffold. (via Semantic Scholar)
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Source: Web Of Science
Added: August 6, 2018

2003 journal article

Using capillary electrophoresis to study methylation effect on RNA-peptide interaction

Acta Biochimica Polonica, 50(3), 857–864.

By: P. Mucha, A. Szyk, P. Rekowski & P. Agris

Source: NC State University Libraries
Added: August 6, 2018

2002 article

Interaction of RNA with phage display selected peptides analyzed by capillary electrophoresis mobility shift assay

MUCHA, P. I. O. T. R., SZYK, A. G. N. I. E. S. Z. K. A., REKOWSKI, P. I. O. T. R., GUENTHER, R. I. C. H. A. R. D., & AGRIS, P. A. U. L. F. (2002, May 1). RNA.

By: P. Mucha n, A. Szyk*, P. Rekowski *, R. Guenther n & P. Agris n

author keywords: anticodon stem and loop; capillary electrophoresis; methylated nucleoside-dependent RNA-peptide; interaction; phage display selected peptides; tRNA
MeSH headings : Amino Acid Sequence; Anticodon / chemistry; Anticodon / genetics; Anticodon / metabolism; Base Sequence; Electrophoresis, Capillary / methods; In Vitro Techniques; Molecular Sequence Data; Nucleic Acid Conformation; Peptide Library; Peptides / chemistry; Peptides / metabolism; RNA, Transfer, Phe / chemistry; RNA, Transfer, Phe / genetics; RNA, Transfer, Phe / metabolism
topics (OpenAlex): RNA and protein synthesis mechanisms; Monoclonal and Polyclonal Antibodies Research; Microfluidic and Capillary Electrophoresis Applications
TL;DR: Capillary electrophoresis was found to be an efficient and sensitive method for the qualitative analysis of RNA/peptide interaction and should be generally applicable to the study of RNA- peptide (protein) interactions. (via Semantic Scholar)
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UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

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