Chi Fu

Works (2)

Updated: July 5th, 2023 16:00

2002 article

Identification and Quantification of Protecting Groups Remaining in Commercial Oligonucleotide Products Using Monoclonal Antibodies

Fu, C., Smith, S., Simkins, S. G., & Agris, P. F. (2002, July 1). Analytical Biochemistry.

By: C. Fu n, S. Smith n, S. Simkins n & P. Agris n

author keywords: DNA; RNA; automated synthesis; protecting group detection; quality control
MeSH headings : Antibodies, Monoclonal / immunology; Antibody Specificity; Chromatography, High Pressure Liquid; DNA / chemistry; DNA / immunology; Enzyme-Linked Immunosorbent Assay; Immunoblotting / methods; Molecular Structure; Oligonucleotides / chemistry; Oligonucleotides / immunology; Quality Control; RNA / chemistry; RNA / immunology; Sensitivity and Specificity; Spectrum Analysis
topics (OpenAlex): RNA and protein synthesis mechanisms; Mass Spectrometry Techniques and Applications; DNA and Nucleic Acid Chemistry
TL;DR: Monoclonal antibodies selectively identify and quantify picomoles of remaining protecting groups on antisense therapeutics and oligonucleotide diagnostics. (via Semantic Scholar)
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Source: Web Of Science
Added: August 6, 2018

2002 personal communication

QC in antisense oligo synthesis

By: P. Agris, S. Smith, C. Fu & S. Simkins

Source: NC State University Libraries
Added: August 6, 2018

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