2002 journal article

Nitration of manganese superoxide dismutase during ocular inflammation


By: K. Pittman n, L. MacMillan-Crow*, B. Peters n & J. Allen n

author keywords: uveitis; nitric oxide; peroxynitrite; nitration; MnSOD; albumin; reactive nitrogen species
MeSH headings : Acute Disease; Albumins / analysis; Animals; Eye Proteins / analysis; Female; Lipopolysaccharides; Peroxynitrous Acid / biosynthesis; RNA, Messenger / genetics; Rats; Rats, Inbred Lew; Superoxide Dismutase / genetics; Superoxide Dismutase / metabolism; Up-Regulation; Uveitis / chemically induced; Uveitis / enzymology
TL;DR: It is confirmed through immunoanalysis that nitrated proteins are produced during EIU, and furthermore, that MnS OD is a target of nitration during the inflammatory response, and two endogenous nitration targets, albumin and MnSOD, were identified. (via Semantic Scholar)
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Source: Web Of Science
Added: August 6, 2018

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