Works (5)
Updated: July 5th, 2023 16:00
2009 journal article
Energy stores are not altered by long-term partial sleep deprivation in Drosophila melanogaster
PLoS One, 4(7).
Source: NC State University Libraries
Added: August 6, 2018
2008 journal article
Quantitative genetic analysis of sleep in Drosophila melanogaster
GENETICS, 178(4), 2341–2360.
MeSH headings : Alleles; Analysis of Variance; Animals; Drosophila melanogaster / genetics; Energy Metabolism / genetics; Female; Gene Expression Regulation; Male; Mutagenesis, Insertional; Phenotype; Quantitative Trait, Heritable; RNA, Messenger / genetics; RNA, Messenger / metabolism; Sex Characteristics; Sleep / genetics; Time Factors; Wakefulness / genetics
TL;DR:
Mutational genetic correlations among sleep parameters revealed that the genetic basis of the transition between sleep and waking states in males and females may be different, suggesting that sleep may serve a number of different functions rather than a single purpose.
(via Semantic Scholar)
open access via www.genetics.org (publisher PDF)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2003 journal article
Strategic selection of hyperthermophilic esterases for resolution of 2-arylpropionic esters
BIOTECHNOLOGY PROGRESS, 19(5), 1410–1416.
MeSH headings : Amino Acid Sequence; Candida / enzymology; Candida / genetics; Catalysis; Enzyme Stability; Esterases / biosynthesis; Esterases / chemistry; Esterases / genetics; Esterases / isolation & purification; Esters; Hydrolysis; Molecular Sequence Data; Naproxen / analogs & derivatives; Naproxen / chemistry; Protein Engineering / methods; Pyrococcus furiosus / enzymology; Pyrococcus furiosus / genetics; Recombinant Proteins / biosynthesis; Recombinant Proteins / chemistry; Sequence Alignment / methods; Sequence Analysis, Protein / methods; Species Specificity; Stereoisomerism; Sulfolobus / enzymology; Sulfolobus / genetics
TL;DR:
The results here show that although bioinformatics tools can be used to select candidate biocatalysts for chiral resolution of 2‐arylpropionic esters, biochemical characterization is needed to definitively determine functional characteristics.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation
(OpenAlex)
12. Responsible Consumption and Production
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2002 journal article
Enantiomeric resolution of 2-aryl propionic esters with hyperthermophilic and mesophilic esterases: Contrasting thermodynamic mechanisms
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 124(28), 8190–8191.
MeSH headings : Candida / enzymology; Carboxylesterase; Carboxylic Ester Hydrolases / chemistry; Esterases / chemistry; Esters / chemistry; Esters / isolation & purification; Lipase / chemistry; Naproxen / chemistry; Naproxen / isolation & purification; Propionates / chemistry; Propionates / isolation & purification; Rhizomucor / enzymology; Stereoisomerism; Substrate Specificity; Sulfolobus / enzymology; Thermodynamics
TL;DR:
The enantiomeric resolution of 2-aryl propionic esters by hyperthermophilic and mesophilic esterases was found to be governed by contrasting thermodynamic mechanisms.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
12. Responsible Consumption and Production
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2002 journal article
Structural and catalytic response to temperature and cosolvents of carboxylesterase EST1 from the extremely thermoacidophilic archaeon Sulfolobus solfataricus P1
BIOTECHNOLOGY AND BIOENGINEERING, 80(7), 784–793.
author keywords: DMSO; conformational flexibility; enzyme activation; thermostable
MeSH headings : Acetonitriles / chemistry; Carboxylesterase; Carboxylic Ester Hydrolases / biosynthesis; Carboxylic Ester Hydrolases / chemistry; Carboxylic Ester Hydrolases / isolation & purification; Catalysis; Dimethyl Sulfoxide / chemistry; Dimethylformamide / chemistry; Dioxanes / chemistry; Enzyme Activation; Enzyme Stability; Molecular Conformation; Quality Control; Sensitivity and Specificity; Solvents / chemistry; Species Specificity; Structure-Activity Relationship; Sulfolobus / classification; Sulfolobus / enzymology; Temperature
TL;DR:
Results suggest cosolvents may also serve as activators in applications involving thermostable biocatalysts at sub-optimal temperatures, related to small changes in the enzyme's structure resulting in an increase in its conformational flexibility.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation
(OpenAlex)
12. Responsible Consumption and Production
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
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