Debra C. Sellon

Works (18)

Updated: July 19th, 2023 10:10

2008 article

Pharmacokinetics of Butorphanol and Evaluation of Physiologic and Behavioral Effects after Intravenous and Intramuscular Administration to Neonatal Foals

JOURNAL OF VETERINARY INTERNAL MEDICINE, Vol. 22, pp. 1417–1426.

By: M. Arguedas*, M. Hines*, M. Papich n , K. Farnsworth* & D. Sellon*

author keywords: Drug disposition; Feeding; Narcotic agonist-antagonist; Pedometer; Sedation
MeSH headings : Analgesics, Opioid / administration & dosage; Analgesics, Opioid / pharmacokinetics; Animals; Animals, Newborn; Behavior, Animal / drug effects; Butorphanol / administration & dosage; Butorphanol / pharmacokinetics; Female; Horses; Injections, Intramuscular; Injections, Intravenous; Male; Time Factors
TL;DR: The main behavioral effects after butorphanol administration to neonatal foals were sedation and increased feeding behavior. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, ORCID
Added: August 6, 2018

2006 journal article

Red maple (Acer rubrum) leaf toxicosis in horses: A retrospective study of 32 cases

JOURNAL OF VETERINARY INTERNAL MEDICINE, 20(5), 1197–1201.

By: A. Alward n, C. Corriher, M. Barton*, D. Sellon*, A. Blikslager n  & S. Jones n 

Contributors: A. Alward n, C. Corriher, M. Barton*, D. Sellon*, A. Blikslager n  & S. Jones n 

author keywords: equidae; Heinz body; hemolysis; methemoglobin
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, ORCID
Added: August 6, 2018

2004 article

Effects of continuous rate intravenous infusion of butorphanol on physiologic and outcome variables in horses after celiotomy

JOURNAL OF VETERINARY INTERNAL MEDICINE, Vol. 18, pp. 555–563.

By: D. Sellon*, M. Roberts n, A. Blikslager n , C. Ulibarri* & M. Papich n 

author keywords: behavior; colic; cortisol; pain management; stress
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, ORCID
Added: August 6, 2018

2004 journal article

Effects of trimethoprim-sulfadiazine on thyroid function of horses

JOURNAL OF VETERINARY INTERNAL MEDICINE, 18(3), 370–373.

By: C. Rothschild*, M. Hines*, B. Breuhaus n , J. Gay & D. Sellon*

author keywords: hypothyroidism; thyroid-stimulating hormone; thyrotropin-releasing hormone
TL;DR: Trimethoprim-sulfadiazine was administered to horses in a randomized, placebo controlled study to determine the effects of potentiated sulfonamides on thyroid function in normal horses. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
5. Gender Equality (Web of Science)
Sources: Web Of Science, ORCID
Added: August 6, 2018

2000 journal article

Hepatic abscesses in three horses

JOURNAL OF THE AMERICAN VETERINARY MEDICAL ASSOCIATION, 216(6), 882-+.

By: D. Sellon*, K. Spaulding*, B. Breuhaus* , L. Katz & R. Mealey

MeSH headings : Animals; Anti-Bacterial Agents / therapeutic use; Female; Horse Diseases / drug therapy; Horse Diseases / pathology; Horse Diseases / surgery; Horses; Liver Abscess / drug therapy; Liver Abscess / surgery; Liver Abscess / veterinary; Male
TL;DR: All horses were euthanatized because of a worsening condition and poor prognosis, and a variety of bacteria were isolated from these abscesses, including Staphylococus aureus and Bacteroides fragilis. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, ORCID
Added: August 6, 2018

1999 journal article

Increased interleukin-6 activity in the serum of ponies acutely infected with equine infectious anaemia virus

RESEARCH IN VETERINARY SCIENCE, 66(1), 77–80.

By: D. Sellon n, K. Russell n, V. Monroe n & K. Walker n

MeSH headings : Animals; Body Temperature; Equine Infectious Anemia / blood; Equine Infectious Anemia / immunology; Horses; Interleukin-6 / blood; Lentivirus / isolation & purification; Lentivirus / pathogenicity; RNA-Directed DNA Polymerase / blood; Time Factors; Virulence
TL;DR: IL-6 production in response to EIAV infection may play a role in pathogenesis of disease, especially the hyperglobulinaemia and apparent polyclonal B cell activation in these horses. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

1999 journal article

Platelets from thrombocytopenic ponies acutely infected with equine infectious anemia virus are activated in vivo and hypofunctional

VIROLOGY, 259(1), 7–19.

By: K. Russell n, P. Perkins*, M. Hoffman *, R. Miller n, K. Walker n, F. Fuller n , D. Sellon n

MeSH headings : Animals; Blood Platelets / pathology; Blood Platelets / virology; Equine Infectious Anemia / blood; Equine Infectious Anemia / complications; Equine Infectious Anemia / pathology; Humans; Infectious Anemia Virus, Equine / isolation & purification; Platelet Activation; Thrombocytopenia / blood; Thrombocytopenia / pathology; Thrombocytopenia / virology
TL;DR: It is concluded that thrombocytopenia in ponies acutely infected with EIAV is regenerative and suggest that bone marrow platelet production is not severely compromised in these ponies. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, ORCID
Added: August 6, 2018

1998 journal article

Hematologic and serum biochemical variables and plasma corticotropin concentration in healthy aged horses

American Journal of Veterinary Research, 59(10), 1247–1251.

By: D. McFarlane, D. Sellon, D. Gaffney, V. Hedgpeth, M. Papich  & S. Gibbs

Source: NC State University Libraries
Added: August 6, 2018

1998 journal article

Hyperglobulinemia and lymphocyte subset changes in naturally infected, in apparent carriers of equine infectious anemia virus

American Journal of Veterinary Research, 59(8), 1009–1015.

By: K. Russell, K. Walker, R. Miller & D. Sellon

Source: NC State University Libraries
Added: August 6, 2018

1998 journal article

Primary erythrocytosis in a 2-year-old Arabian gelding

JOURNAL OF VETERINARY INTERNAL MEDICINE, 12(5), 384–388.

By: D. McFarlane n, D. Sellon n & P. Parker*

MeSH headings : Animals; Diagnosis, Differential; Erythrocyte Count; Horse Diseases / pathology; Horses; Mucous Membrane / pathology; Phlebotomy / veterinary; Polycythemia / diagnosis; Polycythemia / pathology; Polycythemia / veterinary
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

1997 journal article

Flow cytometric method for detecting thiazole orange positive (reticulated) platelets in thrombocytopenic horses

American Journal of Veterinary Research, 58(10), 1092–1096.

By: K. Russell, P. Perkins, C. Grindem, K. Walker & D. Sellon

Source: NC State University Libraries
Added: August 6, 2018

1997 journal article

Nucleic acid amplification for rapid detection of Rhodococcus equi in equine blood and tracheal wash fluids

American Journal of Veterinary Research, 58(11), 1232–1237.

By: D. Sellon, K. Walker, M. Suyemoto & C. Altier

Source: NC State University Libraries
Added: August 6, 2018

1997 journal article

Thrombocytosis in 24 Horses (1989-1994)

Journal of Veterinary Internal Medicine, 11(1), 24–29.

By: D. Sellon n, J. Levine n , K. Palmer n, E. Millikin n, C. Grindem n & P. Covington n

MeSH headings : Anemia / epidemiology; Anemia / veterinary; Animals; Female; Fibrinogen / analysis; Horse Diseases / blood; Horse Diseases / diagnosis; Horse Diseases / epidemiology; Horses; Hypoproteinemia / epidemiology; Hypoproteinemia / veterinary; Leukocytosis / epidemiology; Leukocytosis / veterinary; Male; Multivariate Analysis; North Carolina / epidemiology; Platelet Count / veterinary; Prevalence; Retrospective Studies; Risk Factors; Thrombocytosis / diagnosis; Thrombocytosis / epidemiology; Thrombocytosis / veterinary
TL;DR: The strong association of thrombocytosis with infectious/inflammatory disorders, however, should lead clinicians to suspect these types of conditions in horses with high platelet counts. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, ORCID, Crossref
Added: August 6, 2018

1996 journal article

Equine infectious anemia virus replication is upregulated during differentiation of blood monocytes from acutely infected horses

Journal of Virology, 70(1), 590.

By: D. Sellon, K. Walker, K. Russell, S. Perry, P. Covington & F. Fuller

Source: NC State University Libraries
Added: August 6, 2018

1996 journal article

Phorbol ester stimulation of equine macrophage cultures alters expression of equine infectious anemia virus

Veterinary Microbiology, 52(3-4), 209–221.

By: D. Sellon n, K. Walker n, K. Russell n, S. Perry n & F. Fuller n 

author keywords: equine infectious anemia virus; horse; macrophage
MeSH headings : Animals; Base Sequence; Cell Survival; Cells, Cultured; Equine Infectious Anemia / virology; Gene Expression Regulation, Viral; Horses; Infectious Anemia Virus, Equine / genetics; Infectious Anemia Virus, Equine / physiology; Macrophage Activation / drug effects; Macrophages / drug effects; Macrophages / physiology; Macrophages / virology; Molecular Sequence Data; Repetitive Sequences, Nucleic Acid; Tetradecanoylphorbol Acetate / pharmacology
TL;DR: A significant downregulation of viral expression occurred independent of the virulence of the virus strain used or the nucleic acid sequence of the viral LTR, which may represent an adaptive response of EIAV to evade the host immune response and establish a persistent infection. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, Crossref, ORCID
Added: August 6, 2018

1996 journal article

Risk factors associated with thrombocytopenia in horses

Journal of Veterinary Internal Medicine, 10, 127–132.

By: D. Sellon, J. Levine , E. Millikin, K. Palmer, P. Covington & C. Grindem

Source: NC State University Libraries
Added: August 6, 2018

1996 journal article

Thrombocytopenia in Horses: 35 Cases (1989-1994)

Journal of Veterinary Internal Medicine, 10(3), 127–132.

By: D. Sellon n, J. Levine n , E. Millikin n, K. Palmer n, C. Grindem n & P. Covington n

MeSH headings : Animals; Communicable Diseases / complications; Communicable Diseases / veterinary; Female; Horse Diseases / epidemiology; Horse Diseases / physiopathology; Horses; Inflammation / complications; Inflammation / veterinary; Male; Prevalence; Retrospective Studies; Risk Factors; Thrombocytopenia / epidemiology; Thrombocytopenia / etiology; Thrombocytopenia / physiopathology; Thrombocytopenia / veterinary
TL;DR: Clinical and clinicopathologic variables significantly associated with thrombocytopenia in the final model included increased PCV, increased band neutrophil count, increased total WBC, and decreased plasma protein concentration that were associated with normal platelet counts. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, Crossref, ORCID
Added: August 6, 2018

1993 journal article

Production and characterization of a monoclonal antibody recognizing a cytoplasmic antigen of equine mononuclear phagocytes

Veterinary Immunology and Immunopathology, 36(4), 303–318.

By: D. Sellon*, J. Cullen, L. Whetter, D. Gebhard, L. Coggins & F. Fuller* 

MeSH headings : Animals; Antibodies, Monoclonal / biosynthesis; Antibodies, Monoclonal / immunology; Antibodies, Viral / biosynthesis; Antibody Specificity; Antigens, Viral / immunology; Blotting, Western / veterinary; Equine Infectious Anemia / etiology; Equine Infectious Anemia / immunology; Fluorescent Antibody Technique / veterinary; Horses / immunology; Hybridomas; Immunoglobulin G / biosynthesis; Immunoglobulin G / immunology; Leukocytes, Mononuclear / immunology; Liver / immunology; Lung / immunology; Lymph Nodes / immunology; Macrophages / immunology; Mice; Phagocytes / immunology; Spleen / immunology
TL;DR: An IgG1 mouse monoclonal antibody, designated 1.646, is described which recognizes a cytoplasmic antigen of equine mononuclear phagocytes, which is closely associated with lysosomal membranes. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, Crossref, ORCID
Added: August 6, 2018

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