Xingming Gao

Works (5)

Updated: July 5th, 2023 15:59

2003 review

Boronic acid compounds as potential pharmaceutical agents

[Review of ]. MEDICINAL RESEARCH REVIEWS, 23(3), 346–368.

By: W. Yang n, X. Gao n & B. Wang n

author keywords: boronic acid; enzyme inhibitor; boron neutron; capture agent; antibody mimics; drug delivery
MeSH headings : Acids / chemistry; Acids / pharmacology; Boron Compounds / chemistry; Boron Compounds / pharmacology; Boron Neutron Capture Therapy; Drug Delivery Systems; Enzyme Inhibitors / chemistry; Enzyme Inhibitors / pharmacology; Humans
TL;DR: This study reviews the recent development in boronic acid compounds during the last six years and outlines the priorities for further research into these compounds. (via Semantic Scholar)
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3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2002 journal article

A glucose-selective fluorescence sensor based on boronic acid-diol recognition

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 12(23), 3373–3377.

By: . Karnati n, X. Gao n, S. Gao n, W. Yang n, W. Ni n, S. Sankar n, B. Wang n

MeSH headings : Biosensing Techniques / methods; Boron Compounds / chemical synthesis; Boron Compounds / chemistry; Fluorescence; Fluorescent Dyes / chemical synthesis; Fluorescent Dyes / chemistry; Glucose / analogs & derivatives; Glucose / analysis; Magnetic Resonance Spectroscopy; Sensitivity and Specificity; Spectrometry, Fluorescence
TL;DR: A glucose selective diphenylboronic acid fluorescent sensor (10a) with a K(a) of 1472M(-1) has been synthesized and evaluated and 1H NMR studies indicate that sensor 10a binds with alpha-D-glucofuranose in a bidentate manner (1:1 ratio). (via Semantic Scholar)
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Source: Web Of Science
Added: August 6, 2018

2002 review

Boronic acid-based sensors

[Review of ]. CURRENT ORGANIC CHEMISTRY, 6(14), 1285–1317.

By: W. Wang*, X. Gao* & B. Wang*

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Source: Web Of Science
Added: August 6, 2018

2002 journal article

Catechol pendant polystyrene for solid-phase synthesis

TETRAHEDRON LETTERS, 43(36), 6339–6342.

By: W. Yang n, X. Gao n, G. Springsteen n & B. Wang n

TL;DR: The feasibility of using immobilized catechol to capture boronic acid products for purification and solid-phase transformation was demonstrated and the immobilized pendant polystyrene polymer was prepared from the Merrifield resin via a convenient procedure with high-density loading. (via Semantic Scholar)
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6. Clean Water and Sanitation (OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2002 journal article

Diboronic acids as fluorescent probes for cells expressing sialyl Lewis X

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 12(16), 2175–2177.

By: W. Yang n, S. Gao n, X. Gao n, V. Karnati n, W. Ni n, B. Wang n, W. Hooks *, J. Carson*, B. Weston*

MeSH headings : Animals; Binding Sites; Boronic Acids / chemical synthesis; Boronic Acids / chemistry; Boronic Acids / metabolism; COS Cells; Fluorescence; Gene Expression; Humans; Mice; Molecular Structure; Oligosaccharides / analysis; Oligosaccharides / chemistry; Oligosaccharides / genetics; Sialyl Lewis X Antigen; Staining and Labeling / methods; Tumor Cells, Cultured
TL;DR: A series of fluorescent diboronic acids was synthesized in nine steps as potential sensors for sialyl Lewis X (sLex) and compound 7e was found to show the strongest fluorescence enhancement upon binding with sLex. (via Semantic Scholar)
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation (OpenAlex)
Source: Web Of Science
Added: August 6, 2018

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