Xingming Gao

Works (5)

Updated: July 5th, 2023 15:59

2003 article

Boronic acid compounds as potential pharmaceutical agents

Yang, W., Gao, X., & Wang, B. (2003, February 10). Medicinal Research Reviews.

By: W. Yang n, X. Gao n & B. Wang n

author keywords: boronic acid; enzyme inhibitor; boron neutron; capture agent; antibody mimics; drug delivery
MeSH headings : Acids / chemistry; Acids / pharmacology; Boron Compounds / chemistry; Boron Compounds / pharmacology; Boron Neutron Capture Therapy; Drug Delivery Systems; Enzyme Inhibitors / chemistry; Enzyme Inhibitors / pharmacology; Humans
topics (OpenAlex): Boron Compounds in Chemistry; Organoboron and organosilicon chemistry; Organometallic Complex Synthesis and Catalysis
TL;DR: This study reviews the recent development in boronic acid compounds during the last six years and outlines the priorities for further research into these compounds. (via Semantic Scholar)
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UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2002 article

A glucose-selective fluorescence sensor based on boronicacid-diol recognition

Karnati, V. V., Gao, X., Gao, S., Yang, W., Ni, W., Sankar, S., & Wang, B. (2002, December 1). Bioorganic & Medicinal Chemistry Letters.

By: V. Karnati n, X. Gao n, S. Gao n, W. Yang n, W. Ni n, S. Sankar n, B. Wang n

MeSH headings : Biosensing Techniques / methods; Boron Compounds / chemical synthesis; Boron Compounds / chemistry; Fluorescence; Fluorescent Dyes / chemical synthesis; Fluorescent Dyes / chemistry; Glucose / analogs & derivatives; Glucose / analysis; Magnetic Resonance Spectroscopy; Sensitivity and Specificity; Spectrometry, Fluorescence
topics (OpenAlex): Molecular Sensors and Ion Detection; Luminescence and Fluorescent Materials; Analytical Chemistry and Sensors
TL;DR: A glucose selective diphenylboronic acid fluorescent sensor (10a) with a K(a) of 1472M(-1) has been synthesized and evaluated and 1H NMR studies indicate that sensor 10a binds with alpha-D-glucofuranose in a bidentate manner (1:1 ratio). (via Semantic Scholar)
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UN Sustainable Development Goal Categories
6. Clean Water and Sanitation (OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2002 article

Boronic Acid-Based Sensors

Wang, W., Gao, X., & Wang, B. (2002, December 1). Current Organic Chemistry.

By: W. Wang*, X. Gao* & B. Wang*

topics (OpenAlex): Molecular Sensors and Ion Detection; Advanced Chemical Sensor Technologies
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UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2002 article

Catechol pendant polystyrene for solid-phase synthesis

Yang, W., Gao, X., Springsteen, G., & Wang, B. (2002, September 1). Tetrahedron Letters.

By: W. Yang n, X. Gao n, G. Springsteen n & B. Wang n

topics (OpenAlex): Chemical Synthesis and Analysis; Boron Compounds in Chemistry; Organoboron and organosilicon chemistry
TL;DR: The feasibility of using immobilized catechol to capture boronic acid products for purification and solid-phase transformation was demonstrated and the immobilized pendant polystyrene polymer was prepared from the Merrifield resin via a convenient procedure with high-density loading. (via Semantic Scholar)
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UN Sustainable Development Goal Categories
6. Clean Water and Sanitation (OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2002 article

Diboronic acids as fluorescent probes for cells expressing sialyl lewis X

Yang, W., Gao, S., Gao, X., Karnati, V. V. R., Ni, W., Wang, B., … Weston, B. (2002, August 1). Bioorganic & Medicinal Chemistry Letters.

By: W. Yang n, S. Gao n, X. Gao n, V. Karnati n, W. Ni n, B. Wang n, W. Hooks *, J. Carson*, B. Weston*

MeSH headings : Animals; Binding Sites; Boronic Acids / chemical synthesis; Boronic Acids / chemistry; Boronic Acids / metabolism; COS Cells; Fluorescence; Gene Expression; Humans; Mice; Molecular Structure; Oligosaccharides / analysis; Oligosaccharides / chemistry; Oligosaccharides / genetics; Sialyl Lewis X Antigen; Staining and Labeling / methods; Tumor Cells, Cultured
topics (OpenAlex): Molecular Sensors and Ion Detection; Glycosylation and Glycoproteins Research; Supramolecular Self-Assembly in Materials
TL;DR: A series of fluorescent diboronic acids was synthesized in nine steps as potential sensors for sialyl Lewis X (sLex) and compound 7e was found to show the strongest fluorescence enhancement upon binding with sLex. (via Semantic Scholar)
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation (OpenAlex)
Source: Web Of Science
Added: August 6, 2018

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