Chi-Chung Chou

Works (3)

Updated: July 5th, 2023 15:59

2006 journal article

Expression profiling of human epidermal keratinocyte response following 1-minute JP-8 exposure

CUTANEOUS AND OCULAR TOXICOLOGY, 25(2), 141–153.

By: C. Chou*, J. Yang *, S. Chen*, N. Monteiro-Riviere n , H. Li* & J. Chen *

Contributors: C. Chou*, J. Yang *, S. Chen*, N. Monteiro-Riviere n , H. Li* & J. Chen *

author keywords: cDNA microarray; gene expression; jet fuel; keratinocyte
MeSH headings : Adult; Apoptosis; Cell Adhesion; Colorimetry; DNA Repair; Down-Regulation; Gene Expression Profiling; Humans; Hydrocarbons / pharmacology; Keratinocytes / cytology; Keratinocytes / drug effects; Keratinocytes / metabolism; Nucleic Acid Hybridization; Signal Transduction; Skin / drug effects; Skin / metabolism
TL;DR: Results indicated that human keratinocyte responds to a single dose of JP-8 insult and revealed several cellular processes previously not associated with jet fuel exposure. (via Semantic Scholar)
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Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2003 journal article

The cytotoxicity of jet fuel aromatic hydrocarbons and dose-related interleukin-8 release from human epidermal keratinocytes

Archives of Toxicology, 77(7), 384–391.

By: C. Chou n, J. Riviere n & N. Monteiro-Riviere n 

Contributors: C. Chou n, J. Riviere n & N. Monteiro-Riviere n 

author keywords: aromatic hydrocarbons; cytotoxicity; keratinocytes; interleukin-8; jet fuels
MeSH headings : Aircraft; Cells, Cultured; Epidermal Cells; Fuel Oils / toxicity; Humans; Hydrocarbons, Aromatic / toxicity; Interleukin-8 / metabolism; Keratinocytes / drug effects; Keratinocytes / metabolism; Time Factors
TL;DR: The presence of hexadecane and mineral oil greatly attenuated the cytotoxicity elicited by individual aromatic hydrocarbons in HEK cells and significantly increased with both doses of methylnaphthalene and naphthalenes. (via Semantic Scholar)
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Sources: Web Of Science, ORCID, NC State University Libraries, Crossref, NC State University Libraries
Added: August 6, 2018

2002 journal article

Differential relationship between the carbon chain length of jet fuel aliphatic hydrocarbons and their ability to induce cytotoxicity vs. interleukin-8 release in human epidermal keratinocytes

TOXICOLOGICAL SCIENCES, 69(1), 226–233.

By: C. Chou n, J. Riviere & N. Monteiro-Riviere 

Contributors: C. Chou n, J. Riviere & N. Monteiro-Riviere 

author keywords: keratinocytes; aliphatic hydrocarbons; cytotoxicity; interleukin-8; jet fuels
MeSH headings : Aviation; Cell Survival / drug effects; Cells, Cultured; Epidermal Cells; Fuel Oils / toxicity; Humans; Hydrocarbons / toxicity; Interleukin-8 / metabolism; Keratinocytes / drug effects; Keratinocytes / metabolism; Structure-Activity Relationship
TL;DR: Individual aliphatic hydrocarbons are toxic to HEK cells and are capable of inducing proinflammatory cytokines, indicating a different structure-activity relationship for these two toxicological endpoints in keratinocyte cell cultures. (via Semantic Scholar)
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Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

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