Eric Altermann

Works (32)

Updated: July 5th, 2023 21:18

2010 article

Group-specific comparison of four lactobacilli isolated from human sources using differential blast analysis

Altermann, E., & Klaenhammer, T. R. (2010, October 27). Genes & Nutrition.

By: E. Altermann n & T. Klaenhammer n

author keywords: In silico analysis; PAU; Adhesion; Stress response; Bacteriophage
topics (OpenAlex): Probiotics and Fermented Foods; Genomics and Phylogenetic Studies; Microbial Metabolites in Food Biotechnology
TL;DR: A comparative genomic analysis of four completely sequenced Lactobacillus strains, isolated from the human gastrointestinal tract, versus 25 lactic acid bacterial genomes present in the public database at the time of analysis. (via Semantic Scholar)
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Source: Web Of Science
Added: August 6, 2018

2009 patent

Compositions comprising promoter sequences and methods of use

By: R. Barrangou , A. Azcarate-Peril, E. Altermann, T. Duong & T. Klaenhammer

Source: NC State University Libraries
Added: August 6, 2018

2009 patent

Lactobacillus acidophillus nucleic acid sequences encoding cell surface protein homologues and uses therefore

By: T. Klaenhammer, W. Russell, E. Altermann & B. Buck

Source: NC State University Libraries
Added: August 6, 2018

2009 patent

Lactobacillus acidophilus nucleic acid sequences encoding stress-related proteins and uses therefor

By: T. Klaenhammer, E. Altermann, M. Azcarate-Peril, O. McAuliffe & W. Russell

Source: NC State University Libraries
Added: August 6, 2018

2009 patent

Nucleic acid sequences encoding two-component sensing and regulatory proteins, antimicrobial proteins and uses therefor

By: T. Klaenhammer, W. Russell, E. Altermann & A. Azcarate-Peril

Source: NC State University Libraries
Added: August 6, 2018

2008 article

Analysis of the Genome Sequence ofLactobacillus gasseriATCC 33323 Reveals the Molecular Basis of an Autochthonous Intestinal Organism

Azcarate-Peril, M. A., Altermann, E., Goh, Y. J., Tallon, R., Sanozky-Dawes, R. B., Pfeiler, E. A., … Klaenhammer, T. R. (2008, June 7). Applied and Environmental Microbiology, Vol. 74, pp. 4610–4625.

By: M. Azcarate-Peril  n, E. Altermann n, Y. Goh n, R. Tallon n, R. Sanozky-Dawes n, E. Pfeiler n, S. O'Flaherty n, B. Buck n ...

MeSH headings : Adult; Bacterial Adhesion / genetics; Bacterial Adhesion / physiology; Bacterial Proteins / genetics; Child; DNA Primers; Gastrointestinal Tract / microbiology; Genes, Bacterial; Genome, Bacterial; Humans; Infant, Newborn; Intestines / microbiology; Lactobacillus / genetics; Lactobacillus / isolation & purification; Lactobacillus / pathogenicity; Open Reading Frames
topics (OpenAlex): Probiotics and Fermented Foods; Microbial Metabolites in Food Biotechnology; Gut microbiota and health
TL;DR: The results from this study indicated high intraspecies variability from a genome encoding traits important for survival and retention in the gastrointestinal tract. (via Semantic Scholar)
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Sources: Web Of Science, ORCID
Added: August 6, 2018

2008 article

Functional Genomics of Probiotic Lactobacilli

Klaenhammer, T. R., Altermann, E., Pfeiler, E., Buck, B. L., Goh, Y.-J., O'Flaherty, S., … Duong, T. (2008, September 1). Journal of Clinical Gastroenterology, Vol. 42, pp. S160–S162.

By: T. Klaenhammer n, E. Altermann n, E. Pfeiler n, B. Buck n, Y. Goh n, S. O'Flaherty n, R. Barrangou n , T. Duong n

author keywords: Lactobacillus acidophilus; Lactobacillus johnsonii; Lactobacillus plantarum; Lactobacillus gasseri; genomics; probiotic cultures; lactic acid bacteria
MeSH headings : Animals; Bacterial Proteins / genetics; Bacterial Proteins / metabolism; Evolution, Molecular; Genome, Bacterial; Genomics; Humans; Lactobacillus / classification; Lactobacillus / genetics; Lactobacillus / metabolism; Lactobacillus / physiology; Probiotics / metabolism; Species Specificity
topics (OpenAlex): Probiotics and Fermented Foods; Microbial Metabolites in Food Biotechnology; Gut microbiota and health
TL;DR: A comparative genomic analysis of 4 completely sequenced Lactobacillus strains versus 25 lactic acid bacterial genomes present in the public database at thetime of analysis is conducted. (via Semantic Scholar)
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Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2008 patent

Lactobacillus acidophilus nucleic acid sequences encoding carbohydrate utilization-related proteins and uses therefor

By: T. Klaenhammer, E. Altermann, R. Barrangou , W. Russell & T. Duong

Source: NC State University Libraries
Added: August 6, 2018

2008 patent

Lactobacillus acidophilus nucleic acid sequences encoding cell surface protein homologues and uses therefore

Washington, DC: U.S. Patent and Trademark Office.

By: T. Klaenhammer, E. Altermann, B. Buck & W. Russell

Source: NC State University Libraries
Added: August 6, 2018

2008 patent

Lactobacillus acidophilus nucleic acid sequences encoding protease homologues and uses therefore

By: T. Klaenhammer, E. Altermann & W. Russell

Source: NC State University Libraries
Added: August 6, 2018

2008 patent

Lactobacillus acidophilus nucleic acids and uses thereof

By: T. Klaenhammer, A. Azcarate-Peril & E. Altermann

Source: NC State University Libraries
Added: August 6, 2018

2008 article

S layer protein A of Lactobacillus acidophilus NCFM regulates immature dendritic cell and T cell functions

Konstantinov, S. R., Smidt, H., Vos, W. M., Bruijns, S. C. M., Singh, S. K., Valence, F., … Kooyk, Y. (2008, December 2). Proceedings of the National Academy of Sciences.

By: S. Konstantinov *, H. Smidt *, W. Vos *, S. Bruijns*, S. Singh *, F. Valence, D. Molle, S. Lortal ...

author keywords: lactobacilli; DC-SIGN
MeSH headings : Bacterial Proteins / genetics; Bacterial Proteins / immunology; Bacterial Proteins / metabolism; Cell Differentiation / immunology; Cell Line; Cytokines / metabolism; Dendritic Cells / immunology; Dendritic Cells / microbiology; Immune Tolerance / immunology; Kidney / cytology; Lactobacillus acidophilus / genetics; Lactobacillus acidophilus / immunology; Lactobacillus acidophilus / metabolism; Macrophages / immunology; Macrophages / microbiology; Membrane Glycoproteins / genetics; Membrane Glycoproteins / immunology; Membrane Glycoproteins / metabolism; Mutagenesis; Probiotics; T-Lymphocytes / immunology; T-Lymphocytes / microbiology; Toll-Like Receptor 2 / genetics; Toll-Like Receptor 2 / metabolism; Toll-Like Receptor 4 / genetics; Toll-Like Receptor 4 / metabolism; Transfection
topics (OpenAlex): Immunotherapy and Immune Responses; Escherichia coli research studies; Probiotics and Fermented Foods
TL;DR: The major S layer protein, SlpA, of L. acidophilus NCFM is the first probiotic bacterial DC-SIGN ligand identified that is functionally involved in the modulation of DCs and T cells functions. (via Semantic Scholar)
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Source: Web Of Science
Added: August 6, 2018

2007 article

Influence of the Dairy Environment on Gene Expression and Substrate Utilization in Lactic Acid Bacteria1, ,

Klaenhammer, T. R., Azcarate-Peril, M. A., Altermann, E., & Barrangou, R. (2007, March 1). Journal of Nutrition, Vol. 137, pp. 748S–750.

By: T. Klaenhammer n, M. Azcarate-Peril n, E. Altermann n & R. Barrangou n 

MeSH headings : Animals; Cattle; Dairy Products; Dairying; Environment; Gene Expression Regulation, Bacterial; Lactobacillaceae / genetics; Lactobacillaceae / metabolism; Probiotics
topics (OpenAlex): Probiotics and Fermented Foods; Microbial Metabolites in Food Biotechnology; Gut microbiota and health
TL;DR: Comparative genomics between multiple genomes is providing insights into genes that are important in metabolic, physiological, and functional roles for different LAB in the environments they inhabit, ranging from the gastrointestinal tract to milk and acidified dairy products. (via Semantic Scholar)
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Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2006 article

Comparative Genomics and Transcriptional Analysis of Prophages Identified in theGenomes of Lactobacillus gasseri , Lactobacillussalivarius , and Lactobacillus casei

Ventura, M., Canchaya, C., Bernini, V., Altermann, E., Barrangou, R., McGrath, S., … Sinderen, D. (2006, May 1). Applied and Environmental Microbiology, Vol. 72, pp. 3130–3146.

By: M. Ventura *, C. Canchaya *, V. Bernini *, E. Altermann n, R. Barrangou n , S. McGrath*, M. Claesson *, Y. Li * ...

MeSH headings : Animals; Base Sequence; Genome, Bacterial; Genome, Viral; Genomics; Humans; Lactobacillus / genetics; Lactobacillus / virology; Lacticaseibacillus casei / virology; Molecular Sequence Data; Phylogeny; Prophages / classification; Prophages / genetics; Prophages / isolation & purification; Prophages / metabolism; Sequence Analysis, DNA; Siphoviridae / classification; Siphoviridae / genetics; Siphoviridae / isolation & purification; Siphoviridae / metabolism; Transcription, Genetic; Viral Proteins / genetics; Viral Proteins / metabolism
topics (OpenAlex): Bacteriophages and microbial interactions; Probiotics and Fermented Foods; Genomics and Phylogenetic Studies
TL;DR: Phylogenetic investigation of these newly described prophage sequences revealed that they have not followed an evolutionary development similar to that of their bacterial hosts and that they show a high degree of diversity, even within a species. (via Semantic Scholar)
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Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2006 article

Comparative genomics of the lactic acid bacteria

Makarova, K., Slesarev, A., Wolf, Y., Sorokin, A., Mirkin, B., Koonin, E., … Mills, D. (2006, October 10). Proceedings of the National Academy of Sciences, Vol. 103, pp. 15611–15616.

By: K. Makarova *, A. Slesarev *, Y. Wolf *, A. Sorokin*, B. Mirkin *, E. Koonin *, A. Pavlov *, N. Pavlova* ...

author keywords: evolutionary genomics; fermentation
MeSH headings : Animals; Bacterial Proteins / classification; Bacterial Proteins / genetics; Bacterial Proteins / metabolism; Biological Evolution; Food Microbiology; Gene Transfer, Horizontal; Genome, Bacterial; Genomics; Lactic Acid / metabolism; Lactobacillus / classification; Lactobacillus / genetics; Phylogeny; Streptococcaceae / classification; Streptococcaceae / genetics
topics (OpenAlex): Genomics and Phylogenetic Studies; Probiotics and Fermented Foods; Microbial Metabolites in Food Biotechnology
TL;DR: Phylogenetic analyses, comparison of gene content across the group, and reconstruction of ancestral gene sets indicate a combination of extensive gene loss and key gene acquisitions via horizontal gene transfer during the coevolution of lactic acid bacteria with their habitats. (via Semantic Scholar)
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2. Zero Hunger (OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2005 article

Complete genome sequence of the probiotic lactic acid bacteriumLactobacillus acidophilusNCFM

Altermann, E., Russell, W. M., Azcarate-Peril, M. A., Barrangou, R., Buck, B. L., McAuliffe, O., … Klaenhammer, T. R. (2005, January 25). Proceedings of the National Academy of Sciences, Vol. 102, pp. 3906–3912.

By: E. Altermann n, W. Russell n, M. Azcarate-Peril  n, R. Barrangou n , B. Buck n, O. McAuliffe  n, N. Souther n, A. Dobson n ...

author keywords: adhesion; stress response; proteolytic system; sugar metabolism; in silico analysis
MeSH headings : Bacterial Adhesion / genetics; Bacteriocins / genetics; Bacteriophages / genetics; Bacteriophages / pathogenicity; Carbohydrate Metabolism; Computational Biology; Genome, Bacterial; Lactobacillus acidophilus / genetics; Lactobacillus acidophilus / metabolism; Lactobacillus acidophilus / virology; Molecular Sequence Data; Peptide Hydrolases / genetics; Prophages / genetics; Sequence Analysis, DNA; Transposases / genetics
topics (OpenAlex): Probiotics and Fermented Foods; Microbial Metabolites in Food Biotechnology; Bacteriophages and microbial interactions
TL;DR: These features within the genome sequence of L. acidophilus are likely to contribute to the organisms' gastric survival and promote interactions with the intestinal mucosa and microbiota. (via Semantic Scholar)
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Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2005 article

Functional Analysis of Putative Adhesion Factors in Lactobacillus acidophilus NCFM

Buck, B. L., Altermann, E., Svingerud, T., & Klaenhammer, T. R. (2005, December 1). Applied and Environmental Microbiology.

By: B. Buck n, E. Altermann n, T. Svingerud n & T. Klaenhammer n

MeSH headings : Adhesins, Bacterial / genetics; Adhesins, Bacterial / physiology; Base Sequence; DNA Primers; DNA, Bacterial / genetics; Escherichia coli / genetics; Genome, Bacterial; Lactobacillus acidophilus / classification; Lactobacillus acidophilus / genetics; Lactobacillus acidophilus / physiology; Mucins / metabolism; Phylogeny; Plasmids; Restriction Mapping
topics (OpenAlex): Probiotics and Fermented Foods; Microbial Metabolites in Food Biotechnology; Helicobacter pylori-related gastroenterology studies
TL;DR: It is demonstrated that multiple cell surface proteins in L. acidophilus NCFM can individually contribute to the organism's ability to attach to intestinal cells in vitro. (via Semantic Scholar)
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2005 article

Genomic Perspectives on Probiotic Lactic Acid Bacteria

Klaenhammer, T. R., Peril, A. A., Barrangou, R., Duong, T., & Altermann, E. (2005, January 1). Bioscience and Microflora, Vol. 24, pp. 31–33.

By: T. Klaenhammer n, A. Peril n, R. Barrangou n , T. Duong n & E. Altermann n

topics (OpenAlex): Probiotics and Fermented Foods; Microbial Metabolites in Food Biotechnology; Gut microbiota and health
TL;DR: The genomic content of probiotic Lactobacillus cultures is examined, compared to those lactic acid bacterial genomes that have appeared recently, to illustrate how environmental conditions encountered during biomanufacturing, fermentation, and the gastrointestinal tract can impact gene expression and culture functionality. (via Semantic Scholar)
Sources: NC State University Libraries, ORCID, NC State University Libraries
Added: August 6, 2018

2005 article

Genomic features of lactic acid bacteria effecting bioprocessing and health

KLAENHAMMER, T., BARRANGOU, R., BUCK, B., AZCARATEPERIL, M., & ALTERMANN, E. (2005, May 25). FEMS Microbiology Reviews, Vol. 29, pp. 393–409.

By: T. Klaenhammer n, R. Barrangou n , B. Buck n, M. Azcarateperil n & E. Altermann n

author keywords: lactic acid bacteria; genomics; bioprocessing; probiotics; comparative genomics; functional genomics
MeSH headings : Food Microbiology; Genome, Bacterial; Genomics; Health; Humans; Lactobacillus / genetics; Lactobacillus / growth & development; Lactobacillus / physiology; Lactococcus / genetics; Lactococcus / growth & development; Lactococcus / physiology; Probiotics
topics (OpenAlex): Probiotics and Fermented Foods; Microbial Metabolites in Food Biotechnology; Gut microbiota and health
TL;DR: Genomic analyses of multiple members of the lactic acid bacteria have now elucidated many genetic features that direct their fermentative and probiotic roles, providing an important platform for understanding core mechanisms that control and regulate bacterial growth, survival, signaling, and fermentative processes. (via Semantic Scholar)
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Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2005 article

Microarray Analysis of a Two-Component Regulatory System Involved in Acid Resistance and Proteolytic Activity inLactobacillus acidophilus

Azcarate-Peril, M. A., McAuliffe, O., Altermann, E., Lick, S., Russell, W. M., & Klaenhammer, T. R. (2005, October 1). Applied and Environmental Microbiology.

By: M. Azcarate-Peril  n, O. McAuliffe  n, E. Altermann n, S. Lick  n, W. Russell* & T. Klaenhammer n

MeSH headings : Bacterial Proteins / genetics; Bacterial Proteins / metabolism; Base Sequence; Culture Media; Gene Expression Profiling; Gene Expression Regulation, Bacterial; Histidine Kinase; Hydrogen-Ion Concentration; Lactobacillus acidophilus / genetics; Lactobacillus acidophilus / growth & development; Lactobacillus acidophilus / metabolism; Lactobacillus acidophilus / physiology; Mutation; Oligonucleotide Array Sequence Analysis / methods; Peptide Hydrolases / genetics; Peptide Hydrolases / metabolism; Protein Kinases / genetics; Protein Kinases / metabolism; Signal Transduction
topics (OpenAlex): Probiotics and Fermented Foods; Bacterial Genetics and Biotechnology; Microbial Inactivation Methods
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Source: Web Of Science
Added: August 6, 2018

2005 journal article

PathwayVoyager: pathway mapping using the Kyoto Encyclopedia of Genes and Genomes (KEGG) database

BMC Genomics, 6.

By: E. Altermann & T. Klaenhammer

Source: NC State University Libraries
Added: August 6, 2018

2005 article

Sequence analysis of the Lactobacillus plantarum bacteriophage ΦJL-1

Lu, Z., Altermann, E., Breidt, F., Predki, P., Fleming, H. P., & Klaenhammer, T. R. (2005, March 1). Gene.

By: Z. Lu *, E. Altermann n, F. Breidt  n, P. Predki, H. Fleming* & T. Klaenhammer n

author keywords: bacteriophage; Phi JL-1; sequence analysis; structural proteins; Lactobacillus plantarum
MeSH headings : Amino Acid Sequence; Bacteriolysis / genetics; Bacteriophages / genetics; Bacteriophages / ultrastructure; Chromosome Mapping; DNA Replication / genetics; DNA, Viral / chemistry; DNA, Viral / genetics; Genes / genetics; Genome, Viral; Lactobacillus plantarum / virology; Microscopy, Electron; Molecular Sequence Data; Sequence Analysis, DNA; Sequence Homology, Amino Acid; Viral Structural Proteins / genetics; Virus Assembly / genetics
topics (OpenAlex): Bacteriophages and microbial interactions; Probiotics and Fermented Foods; Genomics and Phylogenetic Studies
TL;DR: The structural gene maps revealed that the order of the head and tail genes is highly conserved among the genomes of several Siphoviridae phages, allowing the assignment of probable functions to certain uncharacterized ORFs from phage PhiJL-1 and other Siphaviridaephages. (via Semantic Scholar)
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2004 article

Epidemic Clone I-Specific Genetic Markers in Strains of Listeria monocytogenes Serotype 4b from Foods

Yildirim, S., Lin, W., Hitchins, A. D., Jaykus, L.-A., Altermann, E., Klaenhammer, T. R., & Kathariou, S. (2004, July 1). Applied and Environmental Microbiology.

By: S. Yildirim n, W. Lin *, A. Hitchins*, L. Jaykus n, E. Altermann n, T. Klaenhammer n, S. Kathariou n

MeSH headings : Base Composition; DNA, Bacterial / analysis; Food Microbiology; Genetic Markers; Listeria monocytogenes / classification; Listeria monocytogenes / genetics; Serotyping
topics (OpenAlex): Listeria monocytogenes in Food Safety; Salmonella and Campylobacter epidemiology; Microbial Inactivation Methods
TL;DR: Examination of 34 serogroup 4 (putative or confirmed serotype 4b) isolates of L. monocytogenes obtained from various foods and food-processing environments, without known implication in illness, revealed that many of these strains had methylation of cytosines at GATC sites in the genome, rendering their DNA resistant to digestion by the restriction endonuclease Sau3AI. (via Semantic Scholar)
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3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2004 article

Epidemic Clone I-Specific Genetic Markers in Strains of Listeria monocytogenes Serotype 4b from Foods

Yildirim, S., Lin, W., Hitchins, A. D., Jaykus, L.-A., Altermann, E., Klaenhammer, T. R., & Kathariou, S. (2004, December 1). Applied and Environmental Microbiology.

By: S. Yildirim*, W. Lin*, A. Hitchins*, L. Jaykus*, E. Altermann*, T. Klaenhammer n, S. Kathariou*

topics (OpenAlex): Listeria monocytogenes in Food Safety; Salmonella and Campylobacter epidemiology; Microbial Inactivation Methods
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3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2004 article

Genetic Markers Unique to Listeria monocytogenes Serotype 4b Differentiate Epidemic Clone II (Hot Dog Outbreak Strains) from Other Lineages

Evans, M. R., Swaminathan, B., Graves, L. M., Altermann, E., Klaenhammer, T. R., Fink, R. C., … Kathariou, S. (2004, April 1). Applied and Environmental Microbiology.

By: M. Evans n, B. Swaminathan*, L. Graves*, E. Altermann n, T. Klaenhammer n, R. Fink n, S. Kernodle n, S. Kathariou n

MeSH headings : Animals; Base Sequence; DNA Primers / genetics; DNA, Bacterial / genetics; Disease Outbreaks; Europe / epidemiology; Food Microbiology; Foodborne Diseases / epidemiology; Foodborne Diseases / microbiology; Genes, Bacterial; Genetic Markers; Humans; Listeria monocytogenes / classification; Listeria monocytogenes / genetics; Listeria monocytogenes / isolation & purification; Listeria monocytogenes / pathogenicity; Meat Products / microbiology; North America / epidemiology; Polymerase Chain Reaction; Serotyping
topics (OpenAlex): Listeria monocytogenes in Food Safety; Salmonella and Campylobacter epidemiology; Microbial Inactivation Methods
TL;DR: The findings suggest that ECII strains have undergone divergence in portions of a serotype-specific region that is conserved in other serotype 4b strains, although the mechanisms that drive this divergence remain to be identified. (via Semantic Scholar)
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3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2004 article

Identification and Inactivation of Genetic Loci Involved withLactobacillus acidophilusAcid Tolerance

Azcarate-Peril, M. A., Altermann, E., Hoover-Fitzula, R. L., Cano, R. J., & Klaenhammer, T. R. (2004, September 1). Applied and Environmental Microbiology.

By: M. Azcarate-Peril n, E. Altermann n, R. Hoover-Fitzula n, R. Cano * & T. Klaenhammer n

MeSH headings : Base Sequence; Calorimetry; DNA Primers; Genome, Bacterial; Hydrogen-Ion Concentration; Lactobacillus acidophilus / genetics; Lactobacillus acidophilus / growth & development; Molecular Sequence Data; Polymerase Chain Reaction; Restriction Mapping
topics (OpenAlex): Polyamine Metabolism and Applications; Probiotics and Fermented Foods; Amino Acid Enzymes and Metabolism
TL;DR: Interestingly, each integrant also exhibited an adaptive acid response during logarithmic growth, indicating that multiple mechanisms are present and orchestrated in L. acidophilus in response to acid challenge. (via Semantic Scholar)
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2004 article

Identification and phenotypic characterization of the cell-division protein CdpA

Altermann, E., Buck, L. B., Cano, R., & Klaenhammer, T. R. (2004, September 29). Gene.

By: E. Altermann n, L. Buck n, R. Cano * & T. Klaenhammer n

author keywords: lactic acid bacteria; lactobacillus; cell adhesion; stress tolerance; functional inactivation; cell wall; cell separation
MeSH headings : Bacterial Adhesion / genetics; Bacterial Adhesion / physiology; Bacterial Proteins / genetics; Bacterial Proteins / metabolism; Caco-2 Cells; Cell Cycle Proteins / genetics; Cell Division / drug effects; Cell Division / genetics; Cell Division / physiology; Cell Wall / metabolism; Culture Media / pharmacology; DNA, Bacterial / chemistry; DNA, Bacterial / genetics; DNA, Bacterial / isolation & purification; Ethanol / pharmacology; Freezing; Gene Silencing; Humans; Lactobacillus acidophilus / drug effects; Lactobacillus acidophilus / genetics; Lactobacillus acidophilus / growth & development; Membrane Glycoproteins / genetics; Molecular Sequence Data; Mutation; Phylogeny; Sequence Analysis, DNA; Sodium Chloride / pharmacology; Temperature
topics (OpenAlex): Probiotics and Fermented Foods; Microbial Metabolites in Food Biotechnology; Enzyme Production and Characterization
TL;DR: It is ascertained that this protein plays a role in cell-wall processing during the growth and cell-cell separation and is designated as cell-division protein, cdpA, based on the in silico and functional analyses. (via Semantic Scholar)
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2004 patent

Lactobacillus acidophilus nucleic acids encoding fructo-oligosaccharide utilization compounds and uses thereof

Washington, DC: U.S. Patent and Trademark Office.

By: R. Barrangou , T. Klaenhammer & E. Altermann

Source: NC State University Libraries
Added: August 6, 2018

2004 article

The genome sequence of the probiotic intestinal bacterium Lactobacillus johnsonii NCC 533

Pridmore, R. D., Berger, B., Desiere, F., Vilanova, D., Barretto, C., Pittet, A.-C., … Schell, M. A. (2004, February 13). Proceedings of the National Academy of Sciences, Vol. 101, pp. 2512–2517.

By: R. Pridmore n, B. Berger  n, F. Desiere n, D. Vilanova n, C. Barretto  n, A. Pittet n, M. Zwahlen n, M. Rouvet n ...

MeSH headings : Biological Transport; Cell Adhesion; Energy Metabolism; Fimbriae, Bacterial / genetics; Genes, Bacterial / genetics; Genome, Bacterial; Humans; Intestinal Mucosa / microbiology; Lactobacillus / genetics; Lactobacillus / metabolism; Lactobacillus / pathogenicity; Molecular Sequence Data; Operon / genetics
topics (OpenAlex): Probiotics and Fermented Foods; Microbial Metabolites in Food Biotechnology; Gut microbiota and health
TL;DR: Genome analysis predicted an abundance of large and unusual cell-surface proteins, including fimbrial subunits, which may be involved in adhesion to glycoproteins or other components of mucin, a characteristic expected to affect persistence in the gastrointestinal tract (GIT). (via Semantic Scholar)
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Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2003 article

Functional and comparative genomic analyses of an operon involved in fructooligosaccharide utilization by Lactobacillus acidophilus

Barrangou, R., Altermann, E., Hutkins, R., Cano, R., & Klaenhammer, T. R. (2003, July 7). Proceedings of the National Academy of Sciences, Vol. 100, pp. 8957–8962.

By: R. Barrangou n , E. Altermann n, R. Hutkins  n, R. Cano  n & T. Klaenhammer n

MeSH headings : ATP-Binding Cassette Transporters / genetics; ATP-Binding Cassette Transporters / metabolism; Bacterial Proteins / genetics; Bacterial Proteins / metabolism; Base Sequence; Biological Transport, Active; Chromosome Mapping; DNA, Bacterial / genetics; Escherichia coli Proteins / genetics; Escherichia coli Proteins / metabolism; Genome, Bacterial; Lac Repressors; Lactobacillus acidophilus / genetics; Lactobacillus acidophilus / metabolism; Molecular Sequence Data; Multigene Family; Mutation; Oligosaccharides / metabolism; Operon; Phenotype; Phylogeny; Repressor Proteins / genetics; Repressor Proteins / metabolism; Sequence Homology, Nucleic Acid; Species Specificity
topics (OpenAlex): Microbial Metabolites in Food Biotechnology; Probiotics and Fermented Foods; Helicobacter pylori-related gastroenterology studies
TL;DR: This is a description of a previously undescribed gene locus involved in transport and catabolism of FOS compounds, which can promote competition of beneficial microorganisms in the human gastrointestinal tract. (via Semantic Scholar)
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Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2003 article

Isolation and characterization of a Lactobacillus plantarum bacteriophage, ΦJL-1, from a cucumber fermentation

Lu, Z., Breidt, F., Fleming, H. P., Altermann, E., & Klaenhammer, T. R. (2003, May 12). International Journal of Food Microbiology.

By: Z. Lu n, F. Breidt n, H. Fleming n, E. Altermann n & T. Klaenhammer n

author keywords: bacteriophage; Lactobacillus plantarum; lactic acid bacteria; vegetable fermentation; cucumber fermentation
MeSH headings : Adsorption; Bacteriophages / genetics; Bacteriophages / isolation & purification; Bacteriophages / physiology; Cucumis sativus / microbiology; Culture Media / chemistry; DNA, Viral / analysis; Electrophoresis, Polyacrylamide Gel; Fermentation; Food Microbiology; Genome, Viral; Hydrogen-Ion Concentration; Kinetics; Lactobacillus / virology
topics (OpenAlex): Bacteriophages and microbial interactions; Probiotics and Fermented Foods; Genomics and Phylogenetic Studies
TL;DR: A virulent Lactobacillus plantarum bacteriophage, PhiJL-1, was isolated from a commercial cucumber fermentation and sequenced to reveal a linear, double-stranded DNA that may be important for the development of controlled vegetable fermentations. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2002 article

Discovering lactic acid bacteria by genomics

Klaenhammer, T., Altermann, E., Arigoni, F., Bolotin, A., Breidt, F., Broadbent, J., … Siezen, R. (2002, January 1).

By: T. Klaenhammer n, E. Altermann n, F. Arigoni*, A. Bolotin*, F. Breidt n, J. Broadbent*, R. Cano *, S. Chaillou ...

MeSH headings : Bifidobacterium / genetics; Fermentation; Genomics; Gram-Positive Bacteria / genetics; Lactobacillus / classification; Lactobacillus / genetics; Lactococcus lactis / classification; Lactococcus lactis / genetics
topics (OpenAlex): Probiotics and Fermented Foods; Genomics and Phylogenetic Studies; Microbial Metabolites in Food Biotechnology
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
15. Life on Land (OpenAlex)
Source: NC State University Libraries
Added: August 6, 2018

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