Wen-hai Feng

Works (2)

Updated: July 5th, 2023 15:59

2003 journal article

Analysis of constitutive cytokine expression by pigs infected in-utero with porcine reproductive and respiratory syndrome virus

VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY, 94(1-2), 35–45.

By: W. Feng n, M. Tompkins n, J. Xu n, H. Zhang* & M. McCaw n

author keywords: porcine reproductive and respiratory syndrome virus; cytokine; delayed type hypersensitivity; peripheral blood mononuclear cells; RT-PCR
MeSH headings : Animals; Cytokines / genetics; Cytokines / immunology; Gene Expression Regulation; Hypersensitivity, Delayed / immunology; Leukocytes, Mononuclear / immunology; Leukocytes, Mononuclear / metabolism; Porcine Reproductive and Respiratory Syndrome / congenital; Porcine Reproductive and Respiratory Syndrome / immunology; Porcine respiratory and reproductive syndrome virus / immunology; Porcine respiratory and reproductive syndrome virus / isolation & purification; RNA, Messenger / analysis; Swine / immunology; Swine / virology
TL;DR: It is concluded that in-utero infection with PRRSV results in significant alteration of cytokine mRNA expression that may cause transient immunomodulation, and at 10 weeks of age the pigs' immune responses seemed to recover. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2002 journal article

Thymocyte and peripheral blood T lymphocyte subpopulation changes in piglets following in utero infection with porcine reproductive and respiratory syndrome virus

VIROLOGY, 302(2), 363–372.

By: W. Feng n, M. Tompkins n, J. Xu n, T. Brown n, S. Laster n, H. Zhang, M. McCaw n

author keywords: PRRSV; thymus; thymocyte; T lymphocyte
MeSH headings : Animals; Animals, Newborn; Female; Infectious Disease Transmission, Vertical; Leukocytes, Mononuclear / immunology; Lymphocyte Count; Porcine Reproductive and Respiratory Syndrome / immunology; Porcine Reproductive and Respiratory Syndrome / virology; Porcine respiratory and reproductive syndrome virus / immunology; Pregnancy; Pregnancy, Animal; Swine; Swine Diseases / immunology; Swine Diseases / virology; T-Lymphocyte Subsets / immunology; Thymus Gland / cytology; Thymus Gland / immunology; Uterus / virology
TL;DR: It is shown that the number of thymocytes undergoing apoptosis was increased twofold in piglets infected with PRRSV and this results help explain the dramatic immunosuppression observed in neonatal animals infected in utero withPRRSV. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

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