Works (25)
Updated: August 16th, 2024 13:38
2006 review
Host and bacterial factors in listeriosis pathogenesis
[Review of ]. VETERINARY MICROBIOLOGY, 114(1-2), 1–15.
author keywords: listeria; pathogenesis; pregnancy; predisposition; veterinary
MeSH headings : Animals; Cytosol / microbiology; Disease Susceptibility / microbiology; Environment; Female; Food Microbiology; Humans; Immunity, Cellular / immunology; Listeria / growth & development; Listeria / pathogenicity; Listeriosis / immunology; Listeriosis / microbiology; Listeriosis / transmission; Mice; Pregnancy; Pregnancy Complications, Infectious / immunology; Pregnancy Complications, Infectious / microbiology; Vacuoles / microbiology
TL;DR:
There are many features of the pathogenesis of listeriosis that have remained mysterious despite the extensive use of the microorganism in the study of cell-mediated immunity and intracellular growth, and Informational advances such as the sequence of the mouse and listerial genomes, and technical advancessuch as the discovery of listersia-susceptible mouse strains, may renew interest in the project.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018
2005 journal article
Pathology of end-stage remodeling in a family of cats with hypertrophic cardiomyopathy
VETERINARY PATHOLOGY, 42(4), 458–467.
author keywords: burned-out phase; dilated phase; end stage; feline; hypertrophic cardiomyopathy; myocardial fibrosis
MeSH headings : Animals; Cardiomyopathy, Hypertrophic / pathology; Cardiomyopathy, Hypertrophic / veterinary; Cat Diseases / pathology; Cats; Fatal Outcome; Female; Histological Techniques / veterinary; In Situ Nick-End Labeling / veterinary; Male; Myocardium / pathology; Ventricular Remodeling / physiology
TL;DR:
The objectives were to describe the pathologic alterations associated with ES-HCM and investigate the pathogenesis in three of the four cats, and to exclude apoptosis or coronary vessel spasm on the basis of the data presented.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018
2005 journal article
Sonic hedgehog is required for cardiac outflow tract and neural crest cell development
DEVELOPMENTAL BIOLOGY, 283(2), 357–372.
author keywords: cardiac; neural crest; migration; pulmonary atresia; tetralogy of Fallot; outflow tract; septation; anterior heart field; Bmp4; repulsion
MeSH headings : Animals; Arteries / embryology; Body Patterning; Branchial Region / embryology; Cell Death; Cell Proliferation; Endoderm / physiology; Female; Heart / embryology; Hedgehog Proteins; Intracellular Signaling Peptides and Proteins; Male; Membrane Proteins / biosynthesis; Mice; Mice, Knockout; Neural Crest / cytology; Neural Crest / embryology; Neural Crest / metabolism; Patched Receptors; Receptors, Cell Surface; Signal Transduction; Trans-Activators / genetics
TL;DR:
This study focuses on the defects in pharyngeal arch and cardiovascular patterning present in Sonic hedgehog (Shh) null mouse embryos and suggests that SHH signaling acts to restrict the domains that NCCs can populate during early stages (e8.5-10.5) of cardiovascular and craniofacial development.
(via Semantic Scholar)
open access via doi.org (publisher)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2004 journal article
Hyperglycemia-induced TGF beta and fibronectin expression in embryonic mouse heart
DEVELOPMENTAL DYNAMICS, 231(1), 179–189.
author keywords: hyperglycemia; TGF beta; fibronectin; embryonic heart; protein; mRNA
MeSH headings : Animals; Embryo, Mammalian / cytology; Embryo, Mammalian / metabolism; Fibronectins / metabolism; Hyperglycemia / metabolism; Mice; Myocardium / cytology; Myocardium / metabolism; RNA, Messenger / metabolism; Transforming Growth Factor beta / metabolism; Transforming Growth Factor beta1; Transforming Growth Factor beta2; Transforming Growth Factor beta3
TL;DR:
It is proposed that TGFβ1 and fibronectin may play a role in diabetes‐induced cardiac dysmorphogenesis and is characterized in the organogenesis‐stage mouse heart.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018
2004 article
Hypoglycemia-induced changes in cell death and cell proliferation in the organogenesis-stage embryonic mouse heart (Retracted article. See vol 76, pg 278, 2006)
Ghatnekar, G. S., Barnes, J. A., Dow, J. L., & Smoak, I. W. (2004, March). BIRTH DEFECTS RESEARCH PART A-CLINICAL AND MOLECULAR TERATOLOGY, Vol. 70, pp. 121–131.
author keywords: embryonic heart; hypoglycemia; apoptosis; cell proliferation; flow cytometry; caspase-3; p53; PCNA
MeSH headings : Animals; Caspase 3; Caspases / metabolism; Cell Death; Cell Division; Flow Cytometry; Heart / embryology; Hypoglycemia / metabolism; Hypoglycemia / pathology; Immunohistochemistry; Mice; Organogenesis; Proliferating Cell Nuclear Antigen / metabolism; Tumor Suppressor Protein p53 / metabolism
TL;DR:
Hypoglycemia reduces embryonic viability, induces significant cell death, and reduces cell proliferation in the E9.5 mouse heart, and these processes may involve active caspase-3 and p53.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018
2004 article
In vivo hyperglycemia and its effect on Glut-1 expression in the embryonic heart
Joyner, N. T., & Smoak, I. W. (2004, July). BIRTH DEFECTS RESEARCH PART A-CLINICAL AND MOLECULAR TERATOLOGY, Vol. 70, pp. 438–448.
author keywords: Glut-1; mouse; embryo; hyperglycemia; heart
MeSH headings : Animals; Female; Gene Expression / physiology; Glucose / metabolism; Glucose Transporter Type 1; Heart / embryology; Hyperglycemia / metabolism; Mice; Monosaccharide Transport Proteins / genetics; Monosaccharide Transport Proteins / metabolism; Pregnancy; RNA, Messenger / metabolism
TL;DR:
Hyperglycemia-induced alterations in Glut-1 expression likely interfere with balance of glucose available to the embryonic heart that may affect cardiac morphogenesis.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018
2003 journal article
Influence of pregnancy on the pathogenesis of listeriosis in mice inoculated intragastrically
INFECTION AND IMMUNITY, 71(9), 5202–5209.
MeSH headings : Animals; Base Sequence; Colon / microbiology; Colony Count, Microbial; DNA, Bacterial / genetics; Enterocytes / microbiology; Female; Listeria monocytogenes / genetics; Listeria monocytogenes / isolation & purification; Listeria monocytogenes / pathogenicity; Listeriosis / complications; Listeriosis / etiology; Liver / microbiology; Mice; Mutagenesis, Insertional; Pregnancy; Pregnancy Complications, Infectious / etiology; Risk Factors; Spleen / microbiology; Virulence / genetics
TL;DR:
The ability of the 4nonb strain to produce a lethal infection in pregnant animals did not correlate with an increased incidence or level of liver and spleen colonization over that in nonpregnant females, but the lethality rate did correlate well with the rate at which embryos and their surrounding decidual covering became infected, suggesting that intrauterine infection could be responsible for the increased disease severity in the gravid females.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018
2002 journal article
C-13-NMR study of hypoglycemia-induced glycolytic changes in embryonic mouse heart
TERATOLOGY, 66(5), 267–272.
MeSH headings : Animals; Carbon Isotopes; Culture Media; Glucose / metabolism; Glycolysis / physiology; Heart / embryology; Hypoglycemia / embryology; Hypoglycemia / metabolism; Magnetic Resonance Spectroscopy; Mice; Mice, Inbred Strains; Myocardium / metabolism; Organ Culture Techniques
TL;DR:
NMR effectively measures glucose and its metabolite, lactate, in the same spectrum and thus determines metabolic flux in the isolated embryonic heart after exposure to hypoglycemia and normoglycemic media, suggesting that 13C-NMR spectroscopy can be used to study glucose metabolism in isolated embryonic hearts exposed to hyp glucosecemia.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2002 journal article
Embryotoxicity of the pesticide mirex in vitro
TERATOGENESIS CARCINOGENESIS AND MUTAGENESIS, 22(4), 239–249.
author keywords: insecticide; early somite mouse embryo; whole-embryo culture; organogenesis; xylene
MeSH headings : Abnormalities, Drug-Induced / embryology; Abnormalities, Drug-Induced / etiology; Animals; Apoptosis / drug effects; Cell Division / drug effects; Embryo, Mammalian / drug effects; Embryo, Mammalian / ultrastructure; Embryonic and Fetal Development / drug effects; Female; Fetal Proteins / biosynthesis; Gestational Age; In Vitro Techniques; Insecticides / toxicity; Mice; Mirex / toxicity; Proliferating Cell Nuclear Antigen / analysis; Somites / drug effects; Yolk Sac / blood supply; Yolk Sac / drug effects
TL;DR:
Mirex is embryotoxic in vitro to early organogenesis stage mouse embryos at concentrations > or =100 microg/ml, but the effects do not appear to be mediated by changes in cell proliferation or apoptotic cell death.
(via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018
2002 journal article
Fgf8 is required for pharyngeal arch and cardiovascular development in the mouse
Development (Cambridge, England), 129(19), 4613–4625.
Source: NC State University Libraries
Added: August 6, 2018
2002 review
Hypoglycemia and embryonic heart development
[Review of ]. FRONTIERS IN BIOSCIENCE-LANDMARK, 7, D307–D318.
author keywords: hypoglycemia; embryo; heart; mouse; in vitro; in vivo; diabetes; morphology; function; metabolism; GRPs; hexokinase; glut-1; review
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
5. Gender Equality
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2002 journal article
Tolbutamide alters glucose transport and metabolism in the embryonic mouse heart
TERATOLOGY, 65(1), 19–25.
MeSH headings : Animals; Culture Techniques; Deoxyglucose / metabolism; Endoplasmic Reticulum Chaperone BiP; Female; Gene Expression; Glucose / metabolism; Glucose Transporter Type 1; Glycolysis / physiology; HSP70 Heat-Shock Proteins / metabolism; Heart / drug effects; Heart / embryology; Heart / physiology; Hexokinase / metabolism; Isotope Labeling; Lactic Acid / metabolism; Male; Membrane Proteins / metabolism; Mice; Monosaccharide Transport Proteins / metabolism; RNA, Messenger; Teratogens / toxicity; Tolbutamide / toxicity
TL;DR:
Tolbutamide stimulates glucose uptake and metabolism in the embryonic heart, as occurs in adult extra-pancreatic tissues, and Glut-1 and HKI, but not GRP78, are likely involved in tolbutamide-induced cardiac dysmorphogenesis.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
5. Gender Equality
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2000 journal article
Glucose-regulated protein 78 (GRP78) is elevated in embryonic mouse heart and induced following hypoglycemic stress
ANATOMY AND EMBRYOLOGY, 202(1), 67–74.
author keywords: stress proteins; mouse embryo; heart; hypoglycemia
MeSH headings : Animals; Antibody Specificity; Blotting, Western; Embryonic and Fetal Development / physiology; Endoplasmic Reticulum Chaperone BiP; Female; Fetal Heart / metabolism; HSP70 Heat-Shock Proteins / metabolism; Heart / embryology; Hypoglycemia / metabolism; Immunoenzyme Techniques; Male; Membrane Proteins / metabolism; Mice; Myocardium / cytology; Myocardium / metabolism; Pregnancy; Rabbits
TL;DR:
Investigation of the distribution and heart levels of glucose regulated protein (GRP) 78 during normal development and in response to hypoglycemia in the mouse shows that GRP78 is strongly expressed with in the heart, neural tube, gut endoderm, somites, and surface ectoderm of mouse embryos during early organogenesis, andGRP78 staining remains prominent in theheart from gestational days 9.5 through 13.5.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2000 journal article
Glut-1 expression and its response to hypoglycemia in the embryonic mouse heart
ANATOMY AND EMBRYOLOGY, 201(5), 327–333.
author keywords: glucose uptake; cardiac development; organogenesis
MeSH headings : Age Factors; Animals; Blotting, Western; Cytochalasin B / pharmacology; Deoxyglucose / pharmacology; Electrophoresis, Polyacrylamide Gel; Embryo, Mammalian; Female; Glucose / metabolism; Glucose / pharmacology; Glucose Transporter Type 1; Heart / drug effects; Heart / embryology; Hypoglycemia / metabolism; Hypoglycemia / physiopathology; Immunohistochemistry; Mice; Mice, Inbred Strains; Monosaccharide Transport Proteins / genetics; Monosaccharide Transport Proteins / metabolism; Myocardium / metabolism; Pregnancy; RNA, Messenger / metabolism; Reverse Transcriptase Polymerase Chain Reaction; Time Factors; Tritium
TL;DR:
The importance of Glut-1 during normal cardiogenesis and in response to hypoglycemia in the embryonic heart is supported and is correlated with changes in cardiac glucose requirements during normal organogenesis.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2000 book
Veterinary embryology and teratology
Weybridge, VT: Cherry Tree Books.
Source: NC State University Libraries
Added: August 6, 2018
1999 journal article
Cromakalim: Embryonic effects and reduction of tolbutamide-induced dysmorphogenesis in vitro
TERATOLOGY, 60(5), 260–264.
TL;DR:
Results support previous findings with diazoxide (K(+) channel opener) and chlorpropamide (sulfonylurea) and further suggest a potential role for K(ATP) channel effects in sulfonylUREa-induced dysmorphogenesis.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
1999 journal article
Expression of glucose-regulated proteins (GRP78 and GRP94) in hearts and fore-limb buds of mouse embryos exposed to hypoglycemia in vitro
CELL STRESS & CHAPERONES, 4(4), 250–258.
TL;DR:
Overall, these data demonstrate the preferential induction of GRPs in the heart as compared to fore-limb buds in mouse embryos exposed to hypoglycemia, suggesting increases in GRP protein levels may be a more reliable biomarker of stress than message levels.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
1999 journal article
Glucose metabolism in mouse embryos exposed to metformin in vitro
TOXICOLOGY IN VITRO, 13(1), 27–33.
author keywords: metformin; mouse embryo; glucose metabolism; in vitro
TL;DR:
Glucose uptake and glycolytic metabolism are increased in early-somite mouse embryos in response to high concentrations of metformin in vitro, and the mechanism of increased glucose uptake appears to involve a cytochalasin B-sensitive glucose transporter.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
1999 journal article
Hexokinase I expression and activity in embryonic mouse heart during early and late organogenesis
HISTOCHEMISTRY AND CELL BIOLOGY, 112(5), 359–365.
MeSH headings : Animals; Blotting, Western; Electrophoresis, Polyacrylamide Gel; Female; Gestational Age; Glycolysis; Heart / embryology; Hexokinase / biosynthesis; Immunohistochemistry; Mice; Myocardium / enzymology; Pregnancy; RNA, Messenger / biosynthesis; Reverse Transcriptase Polymerase Chain Reaction
TL;DR:
A complex regulation of HK-I expression and activity in the embryonic heart during organogenesis is suggested, involving a change in the intrinsic activity of the enzyme with development.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger
(OpenAlex)
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
1998 journal article
Tolbutamide: Placental transfer, tissue distribution, and metabolic effects in murine embryos
Pharmacology and Toxicology, 82(4), 203–208.
Source: NC State University Libraries
Added: August 6, 2018
1997 journal article
Brief hypoglycemia alters morphology, function, and metabolism of the embryonic mouse heart
Reproductive Toxicology (Elmsford, N.Y.), 11(4), 495–502.
Source: NC State University Libraries
Added: August 6, 2018
1997 journal article
Chlorobutanol: maternal serum levels and placental transfer in the mouse
Veterinary and Human Toxicology, 39(5), 287–290.
Source: NC State University Libraries
Added: August 6, 2018
1997 journal article
Comparison of effects of albendazole sulfoxide on in vitro produced bovine embryos and rat embryos
American Journal of Veterinary Research, 58(9), 1038–1042.
Source: NC State University Libraries
Added: August 6, 2018
1997 journal article
Immunolocalization and heart levels of GRP94 in the mouse during post-implantation development
ANATOMY AND EMBRYOLOGY, 196(4), 335–341.
author keywords: stress protein; western blotting; mouse embryo; cardiovascular system; immunohistochemistry
MeSH headings : Animals; Antibodies, Monoclonal; Blotting, Western; Embryo, Nonmammalian / metabolism; Embryonic Development; Female; Gene Expression Regulation, Developmental; HSP70 Heat-Shock Proteins / immunology; HSP70 Heat-Shock Proteins / metabolism; Heart / embryology; Immunohistochemistry; Membrane Proteins / immunology; Membrane Proteins / metabolism; Mice; Myocardium / metabolism; Pregnancy; Time Factors
TL;DR:
The results demonstrate that the stress protein GRP94 is constitutively expressed within specific tissues during post-implantation mouse development and suggest that GRPs may play an important role in the process of myocardial cell differentiation and heart development.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
1996 journal article
Persistent oropharyngeal membrane in a Hereford calf
VETERINARY PATHOLOGY, 33(1), 80–82.
author keywords: calves; cattle; congenital defect; Hereford; oropharyngeal membrane
MeSH headings : Animals; Cattle; Cattle Diseases / diagnosis; Cattle Diseases / pathology; Congenital Abnormalities / diagnosis; Congenital Abnormalities / pathology; Congenital Abnormalities / veterinary; Male; Neck / diagnostic imaging; Oropharynx / abnormalities; Oropharynx / embryology; Oropharynx / pathology; Radiography
TL;DR:
This is the first report of this defect in domestic animals of persistent oropharyngeal membrane found in a 6-day-old Hereford calf, and a barium study demonstrated that food remained within the oral cavity despite a swallowing reflex.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
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