Works (2)

Updated: July 5th, 2023 15:59

2003 article

Insulin-like growth factor (IGF)-I and IGF binding proteins-2, -3, -4, -5 in porcine corpora lutea during the estrous cycle; evidence for inhibitory actions of IGFBP-3

Ge, Z., Miller, E., Nicholson, W., Hedgpeth, V., & Gadsby, J. (2003, July 31). Domestic Animal Endocrinology, Vol. 25, pp. 183–197.

By: Z. Ge n, E. Miller n, W. Nicholson n, V. Hedgpeth n & J. Gadsby n

author keywords: IGF-I; IGFBP-3; progesterone; corpus luteum; pig
MeSH headings : Animals; Blotting, Western / veterinary; Corpus Luteum / chemistry; Corpus Luteum / metabolism; Estrous Cycle / metabolism; Female; Insulin-Like Growth Factor Binding Protein 3 / metabolism; Insulin-Like Growth Factor Binding Proteins / analysis; Insulin-Like Growth Factor Binding Proteins / metabolism; Insulin-Like Growth Factor I / analysis; Insulin-Like Growth Factor I / metabolism; Progesterone / metabolism; Radioimmunoassay / veterinary; Swine / physiology
topics (OpenAlex): Growth Hormone and Insulin-like Growth Factors; Reproductive Physiology in Livestock; Reproductive Biology and Fertility
TL;DR: It is concluded that IGFBP-3 inhibits IGF-I actions in the porcine CL in the estrous cycle and inhibited the steroidogenic actions of IGF, but had no significant actions alone. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2003 article

Steroidogenic responses of pig corpora lutea to insulin-like growth factor I (IGF-I) throughout the oestrous cycle

Miller, E. A., Ge, Z., Hedgpeth, V., & Gadsby, J. E. (2003, February 1). Reproduction, Vol. 125, pp. 241–249.

By: E. Miller n, Z. Ge n, V. Hedgpeth n & J. Gadsby n

topics (OpenAlex): Reproductive Physiology in Livestock; Growth Hormone and Insulin-like Growth Factors; Genetic and phenotypic traits in livestock
TL;DR: IGF-I has steroidogenic actions only on 'young' (days 4-7) pig corpora lutea; endogenous IGF-I and IGFBP are insufficient to modulate progesterone secretion in vitro; and the steroidsogenic actions of IGF- I are mediated via PI-3-kinase. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

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