Works (2)

Updated: July 5th, 2023 15:59

2003 journal article

Insulin-like growth factor (IGF)-I and IGF binding proteins-2,-3,-4,-5 in porcine corpora lutea during the estrous cycle; evidence for inhibitory actions of IGFBP-3

DOMESTIC ANIMAL ENDOCRINOLOGY, 25(2), 183–197.

By: Z. Ge n, E. Miller n, W. Nicholson n, V. Hedgpeth n & J. Gadsby n

author keywords: IGF-I; IGFBP-3; progesterone; corpus luteum; pig
MeSH headings : Animals; Blotting, Western / veterinary; Corpus Luteum / chemistry; Corpus Luteum / metabolism; Estrous Cycle / metabolism; Female; Insulin-Like Growth Factor Binding Protein 3 / metabolism; Insulin-Like Growth Factor Binding Proteins / analysis; Insulin-Like Growth Factor Binding Proteins / metabolism; Insulin-Like Growth Factor I / analysis; Insulin-Like Growth Factor I / metabolism; Progesterone / metabolism; Radioimmunoassay / veterinary; Swine / physiology
TL;DR: It is concluded that IGFBP-3 inhibits IGF-I actions in the porcine CL in the estrous cycle and inhibited the steroidogenic actions of IGF, but had no significant actions alone. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2003 journal article

Steroidogenic responses of pig corpora lutea to insulin-like growth factor I (IGF-I) throughout the oestrous cycle

REPRODUCTION, 125(2), 241–249.

By: E. Miller n, Z. Ge n, V. Hedgpeth n & J. Gadsby n

TL;DR: IGF-I has steroidogenic actions only on 'young' (days 4-7) pig corpora lutea; endogenous IGF-I and IGFBP are insufficient to modulate progesterone secretion in vitro; and the steroidsogenic actions of IGF- I are mediated via PI-3-kinase. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

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