Insulin-like growth factor (IGF)-I and IGF binding proteins-2, -3, -4, -5 in porcine corpora lutea during the estrous cycle; evidence for inhibitory actions of IGFBP-3
Ge, Z., Miller, E., Nicholson, W., Hedgpeth, V., & Gadsby, J. (2003, July 31). Domestic Animal Endocrinology, Vol. 25, pp. 183–197.
author keywords: IGF-I; IGFBP-3; progesterone; corpus luteum; pig
MeSH headings : Animals; Blotting, Western / veterinary; Corpus Luteum / chemistry; Corpus Luteum / metabolism; Estrous Cycle / metabolism; Female; Insulin-Like Growth Factor Binding Protein 3 / metabolism; Insulin-Like Growth Factor Binding Proteins / analysis; Insulin-Like Growth Factor Binding Proteins / metabolism; Insulin-Like Growth Factor I / analysis; Insulin-Like Growth Factor I / metabolism; Progesterone / metabolism; Radioimmunoassay / veterinary; Swine / physiology
topics (OpenAlex): Growth Hormone and Insulin-like Growth Factors; Reproductive Physiology in Livestock; Reproductive Biology and Fertility
TL;DR:
It is concluded that IGFBP-3 inhibits IGF-I actions in the porcine CL in the estrous cycle and inhibited the steroidogenic actions of IGF, but had no significant actions alone.
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