Alexander G. Tkachenko

Works (6)

Updated: July 5th, 2023 15:58
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2008 patent

Nanoparticle delivery vehicle

Washington, DC: U.S. Patent and Trademark Office.

By: S. Franzen , D. Feldheim, A. Tkachenko, M. Godek, J. Ryan & M. Anderson

Source: NC State University Libraries
Added: August 6, 2018

2006 journal article

Mimicking the biological activity of diazobenzo[b]fluorene natural products with electronically tuned diazofluorene analogs

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 16(19), 5148–5151.

By: W. Zeng n, T. Ballard n, A. Tkachenko, V. Burns n, D. Feldheim n & C. Melander n

co-author countries: United States of America 🇺🇸
author keywords: kinamycins; lomaiviticins; DNA cleavage; diazofluorenes; antiproliferative activity
MeSH headings : Animals; Antineoplastic Agents / chemical synthesis; Antineoplastic Agents / pharmacology; Carbazoles / pharmacology; Cell Proliferation / drug effects; DNA Damage / drug effects; Fluorenes / chemical synthesis; Fluorenes / pharmacology; HeLa Cells; Humans; Molecular Mimicry; Structure-Activity Relationship
Source: Web Of Science
Added: August 6, 2018

2006 journal article

RNA-mediated synthesis of palladium nanoparticles on Au surfaces

LANGMUIR, 22(13), 5862–5866.

By: D. Liu n, L. Gugliotti n, T. Wu n, M. Dolska n, A. Tkachenko, M. Shipton n, B. Eaton n, D. Feldheim n

co-author countries: United States of America 🇺🇸
MeSH headings : Base Sequence; Gold / chemistry; In Vitro Techniques; Metal Nanoparticles / chemistry; Metal Nanoparticles / ultrastructure; Microscopy, Electron, Scanning; Nucleic Acid Conformation; Palladium / chemistry; RNA, Catalytic / chemistry; RNA, Catalytic / metabolism; Surface Properties
Source: Web Of Science
Added: August 6, 2018

2004 journal article

Cellular trajectories of peptide-modified gold particle complexes: Comparison of nuclear localization signals and peptide transduction domains

BIOCONJUGATE CHEMISTRY, 15(3), 482–490.

By: A. Tkachenko, H. Xie n, Y. Liu, D. Coleman n, J. Ryan n, W. Glomm n, M. Shipton n, S. Franzen n , D. Feldheim n

co-author countries: United States of America 🇺🇸
MeSH headings : 3T3 Cells; Animals; Biological Transport, Active / physiology; Cell Line, Tumor; Cell Nucleus / drug effects; Cell Nucleus / metabolism; Gene Products, tat / chemistry; Gold / chemistry; Gold / pharmacokinetics; HeLa Cells; Humans; Macromolecular Substances; Mice; Nuclear Localization Signals / drug effects; Nuclear Localization Signals / metabolism; Peptides / chemistry; Peptides / pharmacokinetics; Protein Structure, Tertiary / physiology; Serum Albumin, Bovine / chemistry; Serum Albumin, Bovine / pharmacokinetics; Temperature; Transduction, Genetic
Sources: Web Of Science, ORCID
Added: August 6, 2018

2004 journal article

Preparation of protein gradients through the controlled deposition of protein-nanoparticle conjugates onto functionalized surfaces

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 126(17), 5388–5395.

By: S. Kramer n, H. Xie n, J. Gaff n, . Williamson n, A. Tkachenko, N. Nouri n, D. Feldheim n, D. Feldheim n

co-author countries: United States of America 🇺🇸
MeSH headings : Animals; Axons / drug effects; Axons / physiology; Cattle; Cell Division / drug effects; Cells, Cultured; Chromatography, High Pressure Liquid; Gold Colloid / chemistry; Gold Colloid / pharmacology; Hippocampus / cytology; Metals / chemistry; Microscopy, Fluorescence; Nanotechnology; Neurons / cytology; Neurons / drug effects; Polylysine / chemistry; Rats; Serum Albumin, Bovine / chemistry; Serum Albumin, Bovine / pharmacology; Spectrophotometry
Source: Web Of Science
Added: August 6, 2018

2003 journal article

Critical flocculation concentrations, binding isotherms, and ligand exchange properties of peptide-modified gold nanoparticles studied by UV-visible, fluorescence, and time-correlated single photon counting spectroscopies

ANALYTICAL CHEMISTRY, 75(21), 5797–5805.

By: H. Xie n, A. Tkachenko, W. Glomm n, J. Ryan n, M. Brennaman n, J. Papanikolas  n, S. Franzen  n, D. Feldheim n

co-author countries: United States of America 🇺🇸
MeSH headings : 2,2'-Dipyridyl / analogs & derivatives; 2,2'-Dipyridyl / chemistry; Amino Acid Sequence; Animals; Binding, Competitive; Cattle; Coordination Complexes; Dithionitrobenzoic Acid / chemistry; Flocculation; Fluorescamine / chemistry; Glutathione / chemistry; Gold Colloid / chemistry; Gold Colloid / metabolism; Kinetics; Ligands; Nanotechnology / methods; Particle Size; Peptides / chemistry; Protein Binding; Rhodamines / chemistry; Serum Albumin, Bovine / chemistry; Serum Albumin, Bovine / metabolism; Spectrometry, Fluorescence; Spectrophotometry; Spectrophotometry, Ultraviolet; Succinimides / chemistry; Sulfhydryl Compounds / chemistry
Source: Web Of Science
Added: August 6, 2018