Works (9)
Updated: July 5th, 2023 15:59
2019 journal article
A Novel Porcine Model for the Study of Cerebrospinal Fluid Dynamics: Development and Preliminary Results
FRONTIERS IN NEUROLOGY, 10.
author keywords: CSF; CSF pressure; optic canal; glaucoma; papilledema; space-flight associated neuro-ocular syndrome
TL;DR:
To investigate CSF flow within the orbit, a model for CSF dynamics was created using three medium-sized pigs and head tilting was performed to highlight the role of gravitational dependence within the subarachnoid space.
(via Semantic Scholar)
open access via www.frontiersin.org (publisher PDF)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: November 18, 2019
2019 journal article
Extraction and characterization of lignin from corncob residue after acid-catalyzed steam explosion pretreatment
INDUSTRIAL CROPS AND PRODUCTS, 133, 241–249.
author keywords: Biomass; Steam explosion; Corncob; Enzymatic mild acidolysis lignin; NMR; Antioxidant activity
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation
(OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: July 1, 2019
2012 journal article
Structurally Conserved Nop56/58 N-terminal Domain Facilitates Archaeal Box C/D Ribonucleoprotein-guided Methyltransferase Activity
JOURNAL OF BIOLOGICAL CHEMISTRY, 287(23), 19418–19428.
MeSH headings : Archaeal Proteins / chemistry; Archaeal Proteins / genetics; Archaeal Proteins / metabolism; Chromosomal Proteins, Non-Histone / chemistry; Chromosomal Proteins, Non-Histone / genetics; Chromosomal Proteins, Non-Histone / metabolism; Methanococcales / chemistry; Methanococcales / genetics; Methanococcales / metabolism; Methyltransferases / chemistry; Methyltransferases / genetics; Methyltransferases / metabolism; Protein Binding; Protein Structure, Tertiary; Ribonucleoproteins / chemistry; Ribonucleoproteins / genetics; Ribonucleoproteins / metabolism
TL;DR:
The archaeal Nop56/58 NTD exhibits a conserved domain structure whose exceptionally stable interaction with fibrillarin plays a role in both RNP assembly and methyltransferase activity.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
15. Life on Land
(OpenAlex)
Source: Web Of Science
Added: August 6, 2018
2010 journal article
Structural Basis for Substrate Placement by an Archaeal Box C/D Ribonucleoprotein Particle
MOLECULAR CELL, 39(6), 939–949.
MeSH headings : Archaeal Proteins / chemistry; Archaeal Proteins / genetics; Binding Sites / physiology; Biocatalysis; Chromosomal Proteins, Non-Histone / chemistry; Chromosomal Proteins, Non-Histone / genetics; Chromosomal Proteins, Non-Histone / metabolism; Crystallography, X-Ray; Holoenzymes / chemistry; Holoenzymes / genetics; Holoenzymes / metabolism; Methyltransferases / chemistry; Methyltransferases / genetics; Methyltransferases / metabolism; Models, Molecular; Mutagenesis, Insertional / physiology; Nuclear Proteins / chemistry; Nuclear Proteins / genetics; Nucleic Acid Conformation; Protein Multimerization / physiology; Protein Structure, Quaternary / physiology; Pyrococcus furiosus / enzymology; Pyrococcus furiosus / genetics; RNA, Archaeal / chemistry; RNA, Archaeal / metabolism; RNA, Small Nucleolar / chemistry; Recombinant Proteins / chemistry; Recombinant Proteins / genetics; Ribonucleoproteins, Small Nucleolar / chemistry; Ribonucleoproteins, Small Nucleolar / genetics; Ribonucleoproteins, Small Nucleolar / metabolism; Sequence Deletion / physiology
TL;DR:
The predicted asymmetric nature of the holoenzyme is consistent with previous biochemical data on RNP assembly and provides a simple solution for accommodating base-pairing between the C/D guide RNA and large ribosomal and spliceosomal substrate RNAs.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2009 journal article
Signature amino acids enable the archaeal L7Ae box C/D RNP core protein to recognize and bind the K-loop RNA motif
RNA, 16(1), 79–90.
author keywords: box C/D snoRNA; snoRNP; kink-turn; L7Ae/L30 proteins; RNA-protein interaction
MeSH headings : Amino Acid Motifs / physiology; Amino Acid Sequence; Archaea / genetics; Archaea / metabolism; Archaeal Proteins / chemistry; Archaeal Proteins / genetics; Archaeal Proteins / metabolism; Base Sequence; Binding Sites / genetics; Conserved Sequence; Models, Biological; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Nucleic Acid Conformation; Protein Binding / genetics; RNA, Archaeal / chemistry; RNA, Archaeal / metabolism; Ribonucleoproteins / chemistry; Ribonucleoproteins / genetics; Ribonucleoproteins / metabolism; Sequence Homology, Amino Acid
TL;DR:
These five signature amino acids are distinct for each of the L7Ae/L30 family members, suggesting an evolutionary continuum of these RNA-binding proteins for recognition of the various K-turn motifs contained in their cognate RNAs.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2007 review
In vitro reconstitution and affinity purification of catalytically active archaeal box C/D sRNP complexes
[Review of ]. RNA modification, 425, 263–282.
MeSH headings : Chromatography, Affinity / methods; Chromatography, Ion Exchange / methods; Methanococcaceae; Ribonucleoproteins, Small Nuclear / isolation & purification
TL;DR:
A novel affinity purification scheme that uses differentially tagged core proteins and a sequential three-step affinity selection protocol that yields fully assembled and catalytically active box C/D RNPs.
(via Semantic Scholar)
Source: NC State University Libraries
Added: August 6, 2018
2006 journal article
Assembly of the archaeal box C/D sRNP can occur via alternative pathways and requires temperature-facilitated sRNA remodeling
Journal of Molecular Biology, 362(5), 1025–1042.
MeSH headings : Amino Acid Sequence; Archaea / chemistry; Archaea / genetics; Archaea / metabolism; Archaeal Proteins / chemistry; Archaeal Proteins / genetics; Archaeal Proteins / isolation & purification; Archaeal Proteins / metabolism; Base Sequence; Chromatography, Affinity; Circular Dichroism; Methylation; Models, Biological; Molecular Sequence Data; Mutation; Nucleic Acid Conformation; Protein Binding; RNA, Archaeal / chemistry; RNA, Archaeal / genetics; RNA, Archaeal / metabolism; RNA, Guide, Kinetoplastida / chemistry; RNA, Guide, Kinetoplastida / genetics; RNA, Guide, Kinetoplastida / metabolism; RNA, Small Nucleolar / chemistry; RNA, Small Nucleolar / genetics; RNA, Small Nucleolar / metabolism; Ribonucleoproteins, Small Nuclear / chemistry; Ribonucleoproteins, Small Nuclear / genetics; Ribonucleoproteins, Small Nuclear / metabolism; Temperature
TL;DR:
RNA remodeling appears to be a common and requisite feature of archaeal dual-guide box C/D sR NP assembly and formation of the mature sRNP can follow different assembly pathways in generating catalytically active complexes.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: NC State University Libraries
Added: August 6, 2018
2005 journal article
Conserved spacing between the box C/D and C '/D ' RNPs of the archaeal box C/D sRNP complex is required for efficient 2 '-O-methylation of target RNAs
RNA, 11(3), 285–293.
author keywords: archaeal sRNA; box C/D RNA; box C/D RNP; snoRNA; nucleotide modification
MeSH headings : Archaeal Proteins / metabolism; Base Sequence; DNA Primers; Methylation; Nucleic Acid Conformation; RNA, Archaeal / chemistry; RNA, Archaeal / metabolism; Ribonucleoproteins / metabolism
TL;DR:
The importance of spatially positioning the box C/D and C'/D' RNPs within the sRNP complex for nucleotide modification is investigated for preservation of critical inter-RNP interactions required for efficient box C /D sR NP-guided nucleotide methylation.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2003 journal article
Efficient RNA 2 '-O-methylation requires juxtaposed and symmetrically assembled archaeal box C/D and C '/D ' RNPs
EMBO JOURNAL, 22(15), 3930–3940.
author keywords: Archaea; box C; D RNP; ribonucleotide methylation; snoRNA; sRNA
MeSH headings : Archaea / metabolism; Archaeal Proteins / chemistry; Archaeal Proteins / metabolism; Base Sequence; Methylation; Molecular Sequence Data; Nucleic Acid Conformation; Protein Binding; RNA, Archaeal / chemistry; RNA, Archaeal / metabolism; Ribonucleoproteins / metabolism
TL;DR:
In vitro assembly of an archaeal box C/D sRNP using recombinant core proteins L7, Nop56/58 and fibrillarin has yielded an RNA:protein enzyme that guides methylation from both the terminal box C-D core and internal C′/D′ RNP complexes.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
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