Works (6)
Updated: July 5th, 2023 15:58
2007 article
Dermal toxicity
VETERINARY TOXICOLOGY: BASIC AND CLINICAL PRINCIPLES, pp. 263–276.
TL;DR:
Skin is an essential and dynamic organ that performs important functions including thermoregulation and preventing insensible water loss and has important metabolic, immunological, and neurosensory properties.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2006 chapter
In vivo models
In Dermal absorption models in toxicology and pharmacology (pp. 47–68). New York: Taylor and Francis / CRC Press.
Source: NC State University Libraries
Added: August 6, 2018
2005 journal article
Comparative in vivo toxicity of topical JP-8 jet fuel and its individual hydrocarbon components: Identification of tridecane and tetradecane as key constituents responsible for dermal irritation
TOXICOLOGIC PATHOLOGY, 33(2), 258–266.
Contributors: n, N. Monteiro-Riviere n & J. Riviere n
author keywords: hydrocarbons; skin; in vivo irritation; jet fuel; ultrastructure; pathology
MeSH headings : Administration, Topical; Alkanes / toxicity; Animals; Epidermis / drug effects; Epidermis / ultrastructure; Erythema / chemically induced; Erythema / pathology; Hydrocarbons / chemistry; Hydrocarbons / toxicity; Irritants / chemistry; Irritants / toxicity; Kerosene / toxicity; Swine
TL;DR:
Ulastructural studies depicted that jet fuel HC-induced cleft formation within intercellular lipid lamellar bilayers of the stratum corneum was proportional to the length of in vivo HC exposures and revealed that specific HCs (tridecane and tetradecane) might be the key constituents responsible for jet fuel-induced skin irritation.
(via Semantic Scholar)
open access via journals.sagepub.com (publisher PDF)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018
2005 journal article
Effect of in vivo jet fuel exposure on subsequent in vitro dermal absorption of individual aromatic and aliphatic hydrocarbon fuel constituents
JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART A-CURRENT ISSUES, 68(9), 719–737.
Contributors: n, N. Monteiro-Riviere n , R. Baynes n & J. Riviere n
MeSH headings : Animals; Female; Hydrocarbons / pharmacokinetics; Hydrocarbons / pharmacology; Permeability / drug effects; Skin Absorption / drug effects; Swine
TL;DR:
It is suggested that the preexposure of skin to jet fuel enhances the subsequent in vitro percutaneous absorption of HC, so single-dose absorption data for jet fuel HC from naive skin may not be optimal to predict the toxic potential for repeated exposures.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018
2004 journal article
Comparative mixture effects of JP-8(100) additives on the dermal absorption and disposition of jet fuel hydrocarbons in different membrane model systems
TOXICOLOGY LETTERS, 150(3), 351–365.
author keywords: JP-8(100); mixture effects; comparative absorption; membrane models
MeSH headings : Administration, Topical; Alkanes / pharmacokinetics; Animals; Carbon Radioisotopes; Cell Membrane Permeability / drug effects; Dimethylpolysiloxanes / chemistry; Hydrocarbons / pharmacokinetics; In Vitro Techniques; Membranes, Artificial; Models, Biological; Naphthalenes / pharmacokinetics; Silicones / chemistry; Skin / drug effects; Skin / metabolism; Skin Absorption / drug effects; Swine
TL;DR:
The observations demonstrate that the single membrane system may not be suitable for the final prediction of complex additive interactions in jet fuels and rather a combination of different membrane systems may provide the insight to elucidate the possible mechanism for additive interactions.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2004 journal article
Dose related absorption of JP-8 jet fuel hydrocarbons through porcine skin with quantitative structure permeability relationship analysis
TOXICOLOGY MECHANISMS AND METHODS, 14(3), 159–166.
Contributors: n, R. Baynes n , N. Monteiro-Riviere n , X. Xia n & J. Riviere n
author keywords: absorption; GC-SPME; hydrocarbons; jet fuels; porcine skin; QSPR
TL;DR:
The findings suggested a dose related increase in absorption for naphthalene and dimethyl naphthaene (DMN) in this solvent system by using their physicochemical parameters.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018
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