Works (8)

Updated: July 5th, 2023 15:59

2006 journal article

Effectiveness factor for spatial gradient sensing in living cells

CHEMICAL ENGINEERING SCIENCE, 61(17), 5603–5611.

By: J. Haugh n & I. Schneider n

author keywords: cellular biology and engineering; kinetics; diffusion; mathematical modeling; chemotaxis; cell migration
Sources: Web Of Science, ORCID
Added: August 6, 2018

2006 journal article

Mechanisms of gradient sensing and chemotaxis - Conserved pathways, diverse regulation

CELL CYCLE, 5(11), 1130–1134.

By: I. Schneider* & J. Haugh*

author keywords: signal transduction; cell migration; phosphoinositide 3-kinase; Rho-family GTPases; mathematical modeling; diffusion; wound healing
MeSH headings : Animals; Chemotactic Factors / physiology; Chemotaxis / physiology; Fibroblasts / cytology; Humans; Wound Healing
Sources: Web Of Science, ORCID
Added: August 6, 2018

2005 journal article

Quantitative elucidation of a distinct spatial gradient-sensing mechanism in fibroblasts

JOURNAL OF CELL BIOLOGY, 171(5), 883–892.

By: I. Schneider n & J. Haugh n

MeSH headings : 3T3 Cells; Algorithms; Animals; Chemotaxis / physiology; Dictyostelium / cytology; Dictyostelium / physiology; Fibroblasts / physiology; Mice; Models, Biological; Neutrophils / physiology; Phosphatidylinositol 3-Kinases / metabolism; Platelet-Derived Growth Factor / metabolism; Signal Transduction
Sources: Web Of Science, ORCID
Added: August 6, 2018

2005 journal article

Spatial analysis of 3 ' phosphoinositide signaling in living fibroblasts, III: Influence of cell morphology and morphological polarity

BIOPHYSICAL JOURNAL, 89(2), 1420–1430.

By: I. Schneider n, E. Parrish n & J. Haugh n

MeSH headings : Animals; Cell Polarity / physiology; Cell Size; Kinetics; Metabolic Clearance Rate; Mice; NIH 3T3 Cells; Phosphatidylinositol 3-Kinases / metabolism; Phosphatidylinositols / metabolism; Signal Transduction / physiology
Sources: Web Of Science, ORCID
Added: August 6, 2018

2004 journal article

On the cross-regulation of protein tyrosine phosphatases and receptor tyrosine kinases in intracellular signaling

JOURNAL OF THEORETICAL BIOLOGY, 230(1), 119–132.

By: J. Haugh n, I. Schneider n & J. Lewis n

author keywords: signal transduction; receptor; phosphatase; kinase; phosphorylation
MeSH headings : Animals; Cell Membrane / metabolism; Models, Biological; Phosphorylation; Protein Tyrosine Phosphatases / metabolism; Signal Transduction / physiology; src-Family Kinases / metabolism
Sources: Web Of Science, ORCID
Added: August 6, 2018

2004 journal article

Spatial analysis of 3 ' phosphoinositide signaling in living fibroblasts: I. Uniform stimulation model and bounds on dimensionless groups

BIOPHYSICAL JOURNAL, 86(1), 589–598.

By: J. Haugh n & I. Schneider n

MeSH headings : Animals; Cells, Cultured; Computer Simulation; Diffusion; Fibroblasts / drug effects; Fibroblasts / metabolism; Humans; Microscopy, Fluorescence / methods; Models, Biological; Phosphatidylinositols / metabolism; Platelet-Derived Growth Factor / pharmacology; Reproducibility of Results; Sensitivity and Specificity; Signal Transduction / physiology; Tissue Distribution
Sources: Web Of Science, ORCID
Added: August 6, 2018

2004 journal article

Spatial analysis of 3 ' phosphoinositide signaling in living fibroblasts: II. Parameter estimates for individual cells from experiments

BIOPHYSICAL JOURNAL, 86(1), 599–608.

By: I. Schneider n & J. Haugh n

MeSH headings : Cells, Cultured; Computer Simulation; Diffusion; Fibroblasts / drug effects; Fibroblasts / metabolism; Humans; Microscopy, Fluorescence / methods; Models, Biological; Phosphatidylinositols / metabolism; Platelet-Derived Growth Factor / pharmacology; Reproducibility of Results; Sensitivity and Specificity; Signal Transduction / physiology; Tissue Distribution
Sources: Web Of Science, ORCID
Added: August 6, 2018

2003 journal article

Kinetic analysis of platelet-derived growth factor receptor/phosphoinositide 3-kinase/Akt signaling in fibroblasts

JOURNAL OF BIOLOGICAL CHEMISTRY, 278(39), 37064–37072.

By: C. Park n, I. Schneider* & J. Haugh n

MeSH headings : 3T3 Cells; Animals; Fibroblasts / physiology; Kinetics; Mathematics; Mice; Models, Biological; Phosphatidylinositol 3-Kinases / physiology; Phosphorylation; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins / physiology; Proto-Oncogene Proteins c-akt; Receptors, Platelet-Derived Growth Factor / physiology; Signal Transduction / physiology
Sources: Web Of Science, ORCID
Added: August 6, 2018