Works (5)
Updated: August 16th, 2023 21:17
2008 journal article
Characterization of normal tissue complications in 51 dogs undergoing definitive pelvic region irradiation
VETERINARY RADIOLOGY & ULTRASOUND, 49(1), 85–89.
author keywords: dog; radiation therapy; normal tissue complication; rectal toxicity
MeSH headings : Animals; Colonic Neoplasms / radiotherapy; Colonic Neoplasms / veterinary; Dog Diseases / epidemiology; Dog Diseases / radiotherapy; Dogs; Female; Male; Necrosis / pathology; Necrosis / veterinary; North Carolina / epidemiology; Pedigree; Pelvis / pathology; Prevalence; Radiation Injuries / epidemiology; Radiation Injuries / veterinary; Radiotherapy Dosage / veterinary; Retrospective Studies
TL;DR:
The finding of an association of tumor site to complications may be a spurious finding and the association between field size and complications is not unexpected although absolute difference in field size between dogs with and without complications was small.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018
2006 journal article
A tracer dose of technetium-99m-labeled liposomes can estimate the effect of hyperthermia on intratumoral Doxil extravasation
CLINICAL CANCER RESEARCH, 12(22), 6800–6807.
MeSH headings : Animals; Antibiotics, Antineoplastic / pharmacokinetics; Antibiotics, Antineoplastic / therapeutic use; Combined Modality Therapy / methods; Diagnostic Imaging / methods; Dose-Response Relationship, Drug; Doxorubicin / pharmacokinetics; Doxorubicin / therapeutic use; Drug Carriers / administration & dosage; Feasibility Studies; Female; Fibrosarcoma / therapy; Hyperthermia, Induced / methods; Liposomes / administration & dosage; Liposomes / pharmacokinetics; Radioactive Tracers; Rats; Technetium Tc 99m Exametazime / administration & dosage; Thigh / radiation effects; Tumor Cells, Cultured; Xenograft Model Antitumor Assays
TL;DR:
The use of a radiolabeled tracer has potential value to monitor drug delivery and estimate the effect of an intervention aimed to increase liposomal accumulation, such as local hyperthermia.
(via Semantic Scholar)
open access via clincancerres.aacrjournals.org (publisher PDF)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018
2005 journal article
A comparison of oral and intravenous pimonidazole in canine tumors using intravenous CCI-103F as a control hypoxia marker
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 64(2), 592–602.
author keywords: hypoxia; pimonidazole; CCI-103F; differential metabolism; pH
MeSH headings : Administration, Oral; Animals; Area Under Curve; Cell Hypoxia; Cell Line; Cricetinae; Cricetulus; Dog Diseases / metabolism; Dogs; Feasibility Studies; Hydrogen-Ion Concentration; Injections, Intravenous; Neoplasms / metabolism; Neoplasms / veterinary; Nitroimidazoles / administration & dosage; Nitroimidazoles / pharmacokinetics
TL;DR:
Oral pimonidazole HCl is effective as a hypoxia marker in spontaneously arising canine tumors and selective cellular uptake and concomitant higher levels of binding in regions of Hypoxia at the high end of pH gradients might account for the greater extent of pimonidsazole binding.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018
2004 article
Expression of cyclooxygenase-2 in canine epithelial nasal tumors
VETERINARY RADIOLOGY & ULTRASOUND, Vol. 45, pp. 255–260.
author keywords: canine; cyclooxygenase-2; nasal tumors; radiation therapy
MeSH headings : Adenocarcinoma / enzymology; Adenocarcinoma / veterinary; Animals; Carcinoma, Squamous Cell / enzymology; Carcinoma, Squamous Cell / veterinary; Case-Control Studies; Combined Modality Therapy; Cyclooxygenase 2; Dog Diseases / drug therapy; Dog Diseases / enzymology; Dog Diseases / radiotherapy; Dogs; Gene Expression Regulation, Neoplastic; Immunohistochemistry; Isoenzymes / metabolism; Nose Neoplasms / enzymology; Nose Neoplasms / veterinary; Prostaglandin-Endoperoxide Synthases / metabolism; Records / veterinary; Retrospective Studies
TL;DR:
A combination therapy of irradiation and a selective COX-2 inhibitor appears worthy of clinical investigation in the treatment of canine epithelial nasal tumors.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018
2003 journal article
Renal amyloidosis in a dog with chronic Ehrlichiosis
Schweizer Archiv Fur Tierheilkunde, 145(10), 482–485.
Source: NC State University Libraries
Added: August 6, 2018
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