Works (1)

Updated: July 5th, 2023 15:58

2003 journal article

Evidence that Egfr contributes to cryptic genetic variation for photoreceptor determination in natural populations of Drosophila melanogaster

CURRENT BIOLOGY, 13(21), 1888–1893.

By: I. Dworkin n, A. Palsson n, K. Birdsall n & G. Gibson n

MeSH headings : Alleles; Animals; California; Crosses, Genetic; Drosophila melanogaster / anatomy & histology; Drosophila melanogaster / genetics; Epistasis, Genetic; Female; Genes, erbB-1 / genetics; Genetic Variation; Inbreeding; Linkage Disequilibrium; Male; Photoreceptor Cells, Invertebrate / anatomy & histology; Polymorphism, Single Nucleotide; Selection, Genetic; Sequence Analysis, DNA
TL;DR: Replication of the strongest associations with an independent sample of 302 phenotypically extreme individuals derived from 1000 crosses of Egfr(E1) to freshly trapped males and a tendency for the rarer alleles to have more disrupted eye development suggests that mutation-selection balance is a possible mechanism contributing to maintaining cryptic variation for Egfr. (via Semantic Scholar)
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