Thomas A. Halsey

Works (2)

Updated: July 5th, 2023 15:58

2005 journal article

Co-regulation of Salmonella enterica genes required for virulence and resistance to antimicrobial peptides by SlyA and PhoP/PhoQ

MOLECULAR MICROBIOLOGY, 56(2), 492–508.

By: W. Navarre *, T. Halsey n, D. Walthers*, J. Frye *, M. McClelland *, J. Potter n, L. Kenney *, J. Gunn *, F. Fang *, S. Libby n

MeSH headings : Antimicrobial Cationic Peptides / pharmacology; Bacterial Proteins / pharmacology; Drug Resistance, Bacterial; Gene Expression Regulation, Bacterial; Salmonella enterica / drug effects; Salmonella enterica / genetics; Salmonella enterica / pathogenicity; Virulence / genetics
TL;DR: The absence of almost all SlyA‐activated genes from the Escherichia coli K12 genome suggests that the functional linkage between the SlyA and PhoP/PhoQ regulatory systems arose as Salmonella evolved its distinctive pathogenic lifestyle. (via Semantic Scholar)
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Added: August 6, 2018

2004 journal article

The ferritin-like Dps protein is required for Salmonella enterica serovar typhimurium oxidative stress resistance and virulence

INFECTION AND IMMUNITY, 72(2), 1155–1158.

By: T. Halsey*, A. Vazquez-Torres*, D. Gravdahl*, F. Fang  n & S. Libby*

MeSH headings : Animals; Bacterial Proteins / physiology; DNA-Binding Proteins / physiology; Female; Ferritins / physiology; Mice; Mice, Inbred C3H; Oxidative Stress; Salmonella typhimurium / metabolism; Salmonella typhimurium / pathogenicity; Virulence
TL;DR: Evidence is provided that Dps protectsSalmonella from iron-dependent killing by hydrogen peroxide, promotes Salmonella survival in murine macrophages, and enhances Salmoneella virulence. (via Semantic Scholar)
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Added: August 6, 2018

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