Yanli Liu

author keywords: Pt-end-capped gold nanorods; surface plasmon resonance; hot electrons; photocatalysts; H-2 production

TL;DR: It is shown that gold nanorods are excellent for converting low-energy photons into high-energy hot electrons, which can be used to drive chemical reactions at their surfaces, and Tuning of the surface plasmon resonance wavelength of AuNRs changes the hydrogen gas production rate, indicating that SPR is involved in hot electron generation and photoreduction of hydrogen ions. (via Semantic Scholar)

MeSH headings : Alternative Splicing; Biotinylation; Cell Nucleus / chemistry; Cell Nucleus / drug effects; Cell Nucleus / metabolism; Colloids / chemistry; Endocytosis / drug effects; Endosomes / chemistry; Endosomes / drug effects; Endosomes / metabolism; Genetic Vectors / chemistry; Genetic Vectors / metabolism; Gold / chemistry; Gold / metabolism; HeLa Cells; Humans; Lipids / chemistry; Lipids / pharmacology; Metal Nanoparticles / chemistry; Oligonucleotides, Antisense / chemistry; Oligonucleotides, Antisense / metabolism; Oligonucleotides, Antisense / pharmacology; RNA, Messenger / genetics; Serum Albumin, Bovine / chemistry; Serum Albumin, Bovine / metabolism; Sulfhydryl Compounds / chemistry; Thionucleotides / chemistry; Thionucleotides / metabolism; Thionucleotides / pharmacology; beta-Thalassemia / genetics

TL;DR: It is concluded that sequestration of cargo from the harsh conditions of the endosome is a desirable strategy for cell-targeting nanoparticles. (via Semantic Scholar)

MeSH headings : Amino Acid Sequence; Endocytosis; Gold / chemistry; HeLa Cells; Humans; Molecular Structure; Molecular Weight; Nanoparticles / chemistry; Peptides / chemical synthesis; Peptides / chemistry; Polyethylene Glycols / chemistry; Spectrometry, Fluorescence; Sulfhydryl Compounds / chemistry

TL;DR: The assembly of poly(ethylene glycol) (PEG) and mixed peptide/PEG monolayers on gold nanoparticle surfaces is described to provide useful cues in the assembly of stable peptides/gold nanoparticle bioconjugates capable of being internalized into cells. (via Semantic Scholar)

MeSH headings : 3T3 Cells; Animals; Biological Transport, Active / physiology; Cell Line, Tumor; Cell Nucleus / drug effects; Cell Nucleus / metabolism; Gene Products, tat / chemistry; Gold / chemistry; Gold / pharmacokinetics; HeLa Cells; Humans; Macromolecular Substances; Mice; Nuclear Localization Signals / drug effects; Nuclear Localization Signals / metabolism; Peptides / chemistry; Peptides / pharmacokinetics; Protein Structure, Tertiary / physiology; Serum Albumin, Bovine / chemistry; Serum Albumin, Bovine / pharmacokinetics; Temperature; Transduction, Genetic

TL;DR: Video-enhanced color differential interference contrast microscopy and transmission electron microscopy indicated that transport of nanoparticles into the cytoplasm and nucleus depends on peptide sequence and cell line, and cellular uptake of Tat PTD peptide-gold nanoparticle conjugates was temperature dependent, suggesting an endosomal pathway of uptake. (via Semantic Scholar)