@article{neel_tarigo_tater_grindem_2007, title={Deep and superficial skin scrapings from a feline immunodeficiency virus-positive cat}, volume={36}, ISSN={["0275-6382"]}, url={http://www.scopus.com/inward/record.url?eid=2-s2.0-34047251149&partnerID=MN8TOARS}, DOI={10.1111/j.1939-165X.2007.tb00191.x}, abstractNote={Abstract An 8‐year‐old, neutered male, domestic shorthair cat housed at the North Carolina State University, College of Veterinary Medicine, Laboratory Animal Research facility as part of a research colony was examined because of mulifocal skin lesions. The lesions consisted of patchy alopecia with mild crusting of the periauricular region, neck, and dorsum; periauricular excoriations; marked dorsal seborrhea and scaling; and generalized erythematous papules. A moderate amount of ceruminous exudate was present in both ear canals. Results of testing for feline immunodeficiency virus (FIV) were positive. An ear swab specimen and superficial and deep skin scrapings were obtained, mounted with oil on glass slides, and coverslipped for microscopic examination. Two populations of mites were observed: a large population of slender, long (∼200 μm), adult mites with long, tapering abdomens that comprised two‐thirds of the total body length; and a smaller population of more translucent and shorter mites (∼100 μm) with wide, blunt abdomens that had prominent transverse ridges. The interpretation was demodicosis, with Demodex cati and D gatoi co‐infection. Histologic sections of biopsies from skin lesions on the neck, dorsum, and periauricular area contained a mild perivascular and perifollicular inflammatory infiltrate composed predominantly of histiocytes, lymphocytes, and plasma cells. Diffusely within the follicular lumina and occasionally within the superficial keratin, a myriad of Demodex organisms were observed. Intrafollicular mites were compatible in appearance with D cati whereas those in the corneal layer were suggestive of D gatoi. Demodicosis is an uncommon disease of cats, and rare cases of dual infection have been documented, occasionally in FIV‐infected cats. The dual infection emphasizes the importance of doing both superficial and deep skin scrapings and of recognizing the unique microscopic features of different Demodex mites.}, number={1}, journal={VETERINARY CLINICAL PATHOLOGY}, author={Neel, Jennifer A. and Tarigo, Jaime and Tater, Kathy C. and Grindem, Carol B.}, year={2007}, month={Mar}, pages={101–104} } @article{tater_jackson_paps_hammerberg_2005, title={Effects of routine prophylactic vaccination or administration of aluminum adjuvant alone on allergen-specific serum IgE and IgG responses in allergic dogs}, volume={66}, ISSN={["0002-9645"]}, DOI={10.2460/ajvr.2005.66.1572}, abstractNote={Abstract Objective—To determine the acute corn-specific serum IgE and IgG, total serum IgE, and clinical responses to SC administration of prophylactic vaccines and aluminum adjuvant in corn-allergic dogs. Animals—20 allergic and 8 nonallergic dogs. Procedure—17 corn-allergic dogs were vaccinated. Eight clinically normal dogs also were vaccinated as a control group. Serum corn-specific IgE, corn-specific IgG, and total IgE concentrations were measured in each dog before vaccination and 1 and 3 weeks after vaccination by use of an ELISA. The corn-allergic dogs also had serum immunoglobulin concentrations measured at 8 and 9 weeks after vaccination. Twenty allergic dogs received a SC injection of aluminum adjuvant, and serum immunoglobulin concentrations were measured in each dog 1, 2, 3, 4, and 8 weeks after injection. The allergic dogs were examined during the 8 weeks after aluminum administration for clinical signs of allergic disease. Results—The allergic dogs had significant increases in serum corn-specific IgE and IgG concentrations 1 and 3 weeks after vaccination but not 8 or 9 weeks after vaccination. Control dogs did not have a significant change in serum immunoglobulin concentrations after vaccination. After injection of aluminum adjuvant, the allergic dogs did not have a significant change in serum immunoglobulin concentrations or clinical signs. Conclusions and Clinical Relevance—Allergen-specific IgE and IgG concentrations increase after prophylactic vaccination in allergic dogs but not in clinically normal dogs. Prophylactic vaccination of dogs with food allergies may affect results of serologic allergen-specific immunoglobulin testing performed within 8 weeks after vaccination. (Am J Vet Res 2005;66:1572–1577)}, number={9}, journal={AMERICAN JOURNAL OF VETERINARY RESEARCH}, author={Tater, KC and Jackson, HA and Paps, J and Hammerberg, B}, year={2005}, month={Sep}, pages={1572–1577} } @article{olivry_jackson_murphy_tater_roberts_2005, title={Evaluation of a point-of-care immunodot assay for predicting results of allergen-specific intradermal and immunoglobulin E serological tests}, volume={16}, ISSN={["0959-4493"]}, url={http://www.scopus.com/inward/record.url?eid=2-s2.0-18544380343&partnerID=MN8TOARS}, DOI={10.1111/j.1365-3164.2005.00442.x}, abstractNote={Abstract  Immunotherapy to prevent recurrence of clinical signs of atopic dermatitis (AD) is based on intradermal or serological tests that assist in identifying allergen‐specific immunoglobulin E hypersensitivities. Unfortunately, the results of such tests can be negatively influenced by several factors, which include the age of the patients, the season of testing and the administration of anti‐allergic drugs. Screening to predict when these expensive tests will be useful would benefit owners of dogs with AD. The objectives of this study were to determine whether a point‐of‐care allergen‐specific immunodot assay (Allercept E‐Screen©, Heska Corp., Ft Collins, CO, USA) could predict results of either intradermal or Allercept© full panel serological tests in atopic dogs. Thirty dogs living in the south‐eastern USA were diagnosed with AD in accordance with current standards. Allergen‐specific intradermal, serological and E‐Screen© tests were performed in all subjects. For flea, house dust mite and pollen allergens altogether, results of the E‐Screen© assay agreed with those of intradermal and serological tests in 26/30 dogs (87%) and 25/30 dogs (83%), respectively. In this group of dogs, the probabilities of obtaining intradermal or serological tests positive for these allergens were 70 and 67%, respectively. If either skin or serum tests were performed only in dogs with positive E‐Screen© tests, the probability of obtaining positive results would be increased from 70 to 95% and from 67 to 90%, respectively. In this population of dogs with AD, results of the E‐Screen© point‐of‐care immunodot assay was found to often agree with those of allergen‐specific intradermal or Allercept© tests for selected allergen groups.}, number={2}, journal={VETERINARY DERMATOLOGY}, author={Olivry, T and Jackson, HA and Murphy, KM and Tater, KC and Roberts, M}, year={2005}, month={Apr}, pages={117–120} }