Florence C. Fevrier

Works (6)

Updated: July 5th, 2023 15:57

2007 patent

Regioselective halogenation of nicotine and substituted nicotines

Washington, DC: U.S. Patent and Trademark Office.

By: D. Comins, F. Fevrier & E. Smith

Source: NC State University Libraries
Added: August 6, 2018

2006 patent

Regioselective halogenation of nicotine and substituted nicotines

Washington, DC: U.S. Patent and Trademark Office.

By: D. Comins, F. Fevrier & E. Smith

Source: NC State University Libraries
Added: August 6, 2018

2005 article

Diels−Alder Reactions of N-Acyl-2-alkyl(aryl)-5-vinyl-2,3-dihydro-4-pyridones

Comins, D. L., Kuethe, J. T., Miller, T. M., Février, F. C., & Brooks, C. A. (2005, May 25). The Journal of Organic Chemistry.

By: D. Comins n, J. Kuethe n, T. Miller n, F. Février n & C. Brooks n

MeSH headings : Alcohols / chemical synthesis; Amino Acids / chemical synthesis; Combinatorial Chemistry Techniques; Cyclization; Ketones / chemical synthesis; Molecular Structure; Pyridones / chemistry; Stereoisomerism
topics (OpenAlex): Chemical synthesis and alkaloids; Advanced Synthetic Organic Chemistry; Asymmetric Synthesis and Catalysis
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6. Clean Water and Sanitation (OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2005 article

Regioselective C-2 and C-6 Substitution of (S)-Nicotine and Nicotine Derivatives

Février, F. C., Smith, E. D., & Comins, D. L. (2005, November 1). Organic Letters.

By: F. Février n, E. Smith n & D. Comins n

MeSH headings : Combinatorial Chemistry Techniques; Molecular Structure; Nicotine / analogs & derivatives; Nicotine / chemical synthesis; Nicotine / chemistry; Pyridines / chemistry; Stereoisomerism
topics (OpenAlex): Nicotinic Acetylcholine Receptors Study; Fluorine in Organic Chemistry; Asymmetric Synthesis and Catalysis
TL;DR: Regioselective deprotonations of (S)-nicotine and derivatives at the C-2 and C-6 positions of the pyridine ring were performed in good to excellent yields. (via Semantic Scholar)
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Source: Web Of Science
Added: August 6, 2018

2005 article

Synthesis of C-4 Substituted Nicotine Derivatives via an N-Acylpyridinium Salt of (S)-Nicotine

Comins, D. L., King, L. S., Smith, E. D., & Février, F. C. (2005, September 28). Organic Letters.

By: D. Comins n, L. King n, E. Smith n & F. Février n

MeSH headings : Molecular Structure; Nicotine / analogs & derivatives; Nicotine / chemical synthesis; Nicotine / chemistry; Pyridinium Compounds / chemistry; Silanes / chemistry; Sulfur / chemistry
topics (OpenAlex): Nicotinic Acetylcholine Receptors Study; Synthesis and Biological Evaluation; Chemical synthesis and alkaloids
TL;DR: A variety of novel nicotine derivatives were prepared from (S)-nicotine via a two-step sequence through addition of a cuprate reagent to an N-acylpyridinium salt of nicotine, followed by aromatization with elemental sulfur. (via Semantic Scholar)
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UN Sustainable Development Goal Categories
6. Clean Water and Sanitation (OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2005 article

Synthesis of Nicotine Derivatives via Reductive Disilylation of (S)-Nicotine

Smith, E. D., Février, F. C., & Comins, D. L. (2005, December 22). Organic Letters.

By: E. Smith n, F. Février n & D. Comins n

MeSH headings : Catalysis; Lithium / chemistry; Molecular Structure; Nicotine / analogs & derivatives; Nicotine / chemical synthesis; Nicotine / chemistry; Oxidation-Reduction; Silanes / chemistry; Stereoisomerism
topics (OpenAlex): Nicotinic Acetylcholine Receptors Study; Synthesis and Biological Evaluation; Radical Photochemical Reactions
TL;DR: A variety of novel nicotine derivatives were prepared via reductive disilylation of (S)-nicotine via addition of various carbonyl electrophiles and a catalytic amount of TBAF provided either C-5 substituted nicotines or 1,4-dihydronicotine derivatives. (via Semantic Scholar)
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Source: Web Of Science
Added: August 6, 2018

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