Florence C. Fevrier

Works (6)

Updated: July 5th, 2023 15:57

2007 patent

Regioselective halogenation of nicotine and substituted nicotines

Washington, DC: U.S. Patent and Trademark Office.

By: D. Comins, F. Fevrier & E. Smith

Source: NC State University Libraries
Added: August 6, 2018

2006 patent

Regioselective halogenation of nicotine and substituted nicotines

Washington, DC: U.S. Patent and Trademark Office.

By: D. Comins, F. Fevrier & E. Smith

Source: NC State University Libraries
Added: August 6, 2018

2006 journal article

Synthesis of nicotine derivatives via reductive disilylation of (S)-nicotine

ORGANIC LETTERS, 8(2), 179–182.

By: E. Smith n, F. Fevrier n & D. Comins n

MeSH headings : Catalysis; Lithium / chemistry; Molecular Structure; Nicotine / analogs & derivatives; Nicotine / chemical synthesis; Nicotine / chemistry; Oxidation-Reduction; Silanes / chemistry; Stereoisomerism
TL;DR: A variety of novel nicotine derivatives were prepared via reductive disilylation of (S)-nicotine via addition of various carbonyl electrophiles and a catalytic amount of TBAF provided either C-5 substituted nicotines or 1,4-dihydronicotine derivatives. (via Semantic Scholar)
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Source: Web Of Science
Added: August 6, 2018

2005 journal article

Diels-alder reactions of N-acyl-2-alkyl(aryl)-5-vinyl-2,3-dihydro-4-pyridones

JOURNAL OF ORGANIC CHEMISTRY, 70(13), 5221–5234.

By: D. Comins n, J. Kuethe n, T. Miller n, F. Fevrier n & C. Brooks n

MeSH headings : Alcohols / chemical synthesis; Amino Acids / chemical synthesis; Combinatorial Chemistry Techniques; Cyclization; Ketones / chemical synthesis; Molecular Structure; Pyridones / chemistry; Stereoisomerism
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Source: Web Of Science
Added: August 6, 2018

2005 journal article

Regioselective C-2 and C-6 substitution of (S)-nicotine and nicotine derivatives

ORGANIC LETTERS, 7(24), 5457–5460.

By: F. Fevrier n, E. Smith n & D. Comins n

MeSH headings : Combinatorial Chemistry Techniques; Molecular Structure; Nicotine / analogs & derivatives; Nicotine / chemical synthesis; Nicotine / chemistry; Pyridines / chemistry; Stereoisomerism
TL;DR: Regioselective deprotonations of (S)-nicotine and derivatives at the C-2 and C-6 positions of the pyridine ring were performed in good to excellent yields. (via Semantic Scholar)
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Source: Web Of Science
Added: August 6, 2018

2005 journal article

Synthesis of C-4 substituted nicotine derivatives via an N-acylpyridinium salt of (S)-nicotine

ORGANIC LETTERS, 7(22), 5059–5062.

By: D. Comins n, L. King n, E. Smith n & F. Fevrier n

MeSH headings : Molecular Structure; Nicotine / analogs & derivatives; Nicotine / chemical synthesis; Nicotine / chemistry; Pyridinium Compounds / chemistry; Silanes / chemistry; Sulfur / chemistry
TL;DR: A variety of novel nicotine derivatives were prepared from (S)-nicotine via a two-step sequence through addition of a cuprate reagent to an N-acylpyridinium salt of nicotine, followed by aromatization with elemental sulfur. (via Semantic Scholar)
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Source: Web Of Science
Added: August 6, 2018

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