Glicerio A. Ignacio

Works (2)

Updated: July 5th, 2023 15:57

2007 article

Failure of TLR4-Driven NF- κ B Activation to Stimulate Virus Replication in Models of HIV Type 1 Activation

Nordone, S. K., Ignacio, G. A., Su, L., Sempowski, G. D., Golenbock, D. T., Li, L., & Dean, G. A. (2007, November 1). AIDS Research and Human Retroviruses.

By: S. Nordone n, G. Ignacio n, L. Su *, G. Sempowski *, D. Golenbock *, L. Li *, G. Dean n

MeSH headings : Cell Line; HIV Infections / immunology; HIV Infections / virology; HIV-1 / physiology; Humans; Interleukin-1 / biosynthesis; Interleukin-6 / biosynthesis; Lipopolysaccharides / immunology; NF-kappa B / metabolism; Toll-Like Receptor 2 / metabolism; Toll-Like Receptor 4 / metabolism; Toll-Like Receptor 9 / metabolism; Virus Replication
topics (OpenAlex): Immune Response and Inflammation; HIV Research and Treatment; Immune Cell Function and Interaction
TL;DR: It is suggested that although several TLR can upregulate NF-kappaB in HIV-1-infected cells, upregulation of NF-KappaB alone is insufficient to activate the viral LTR, and the possibility that TLR4 signaling pathways may be altered during chronic HIV- 1 infection is raised. (via Semantic Scholar)
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Source: Web Of Science
Added: August 6, 2018

2005 article

Toll-like receptor expression in feline lymphoid tissues

Ignacio, G., Nordone, S., Howard, K. E., & Dean, G. A. (2005, April 11). Veterinary Immunology and Immunopathology.

By: G. Ignacio n, S. Nordone n, K. Howard n & G. Dean n

author keywords: toll-like receptors; feline; feline immunodeficiency virus; innate immunity
MeSH headings : Animals; Base Sequence; Cat Diseases / genetics; Cat Diseases / immunology; Cats / genetics; Cats / immunology; Cell Line; Cloning, Molecular; DNA Primers / genetics; Gene Expression; Immunodeficiency Virus, Feline / pathogenicity; Lentivirus Infections / genetics; Lentivirus Infections / immunology; Lentivirus Infections / veterinary; Lymphocyte Subsets / immunology; Lymphoid Tissue / immunology; Membrane Glycoproteins / genetics; Polymerase Chain Reaction / methods; Polymerase Chain Reaction / veterinary; RNA, Messenger / genetics; RNA, Messenger / metabolism; Receptors, Cell Surface / genetics; Tissue Distribution; Toll-Like Receptors
topics (OpenAlex): Immune Response and Inflammation; Antimicrobial Peptides and Activities; Immune Cell Function and Interaction
TL;DR: Results demonstrate that tissue distribution of TLRs is associated with the immunological role of a particular tissue, that lymphocytes may also express these 'innate immune' receptors, and that FIV infection can alter TLR expression. (via Semantic Scholar)
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Source: Web Of Science
Added: August 6, 2018

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