@article{connor_hallen_lalush_sumner_zhong_2009, place={UK}, title={Comparison of diffraction-enhanced computed tomography and monochromatic synchrotron radiation computed tomography of human trabecular bone}, volume={54}, ISSN={["1361-6560"]}, url={http://dx.doi.org/10.1088/0031-9155/54/20/006}, DOI={10.1088/0031-9155/54/20/006}, abstractNote={Diffraction-enhanced imaging (DEI) is an x-ray-based medical imaging modality that, when used in tomography mode (DECT), can generate a three-dimensional map of both the apparent absorption coefficient and the out-of-plane gradient of the index of refraction of the sample. DECT is known to have contrast gains over monochromatic synchrotron radiation CT (SRCT) for soft tissue structures. The goal of this experiment was to compare contrast-to-noise ratio (CNR) and resolution in images of human trabecular bone acquired using SRCT with images acquired using DECT. All images were acquired at the National Synchrotron Light Source (Upton, NY, USA) at beamline X15 A at an x-ray energy of 40 keV and the silicon [3 3 3] reflection. SRCT, apparent absorption DECT and refraction DECT slice images of the trabecular bone were created. The apparent absorption DECT images have significantly higher spatial resolution and CNR than the corresponding SRCT images. Thus, DECT will prove to be a useful tool for imaging applications in which high contrast and high spatial resolution are required for both soft tissue features and bone.}, number={20}, journal={PHYSICS IN MEDICINE AND BIOLOGY}, author={Connor, D. M. and Hallen, H. D. and Lalush, D. S. and Sumner, D. R. and Zhong, Z.}, year={2009}, month={Oct}, pages={6123–6133} } @article{connor_sayers_sumner_zhong_2006, title={Diffraction enhanced imaging of controlled defects within bone, including bone-metal gaps}, volume={51}, number={12}, journal={Physics in Medicine & Biology}, author={Connor, D. M. and Sayers, D. and Sumner, D. R. and Zhong, Z.}, year={2006}, pages={3283–3300} } @article{connor_sayers_sumner_zhong_2005, title={Identification of fatigue damage in cortical bone by diffraction enhanced imaging}, volume={548}, ISSN={["1872-9576"]}, DOI={10.1016/j.nima.2005.03.095}, abstractNote={In an effort to explore Diffraction Enhanced Imaging of bone tissue, experiments were performed to determine if it was possible to use Diffraction Enhanced Imaging to detect microdamage in bovine cortical bone. Measurements were made at the National Synchrotron Light Source where pre- and post-fatigue rocking curve widths of the bone were studied. The rocking curve widths were then compared. Since no consistent pattern of narrowing or broadening of the rocking curve emerged, it is likely that the ultra-small-angle X-ray scattering present in the bone overshadowed any additional changes to rocking curve caused by microdamage of the bone. Larger bone structures were able to be visualized which suggests that microdamage may be visualized with a higher resolution detector.}, number={1-2}, journal={NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH SECTION A-ACCELERATORS SPECTROMETERS DETECTORS AND ASSOCIATED EQUIPMENT}, author={Connor, DM and Sayers, D and Sumner, DR and Zhong, Z}, year={2005}, month={Aug}, pages={234–239} }