Helen Ying Wang

Works (3)

Updated: July 5th, 2023 15:57

2017 journal article

Agonist-mediated assembly of the crustacean methyl farnesoate receptor

Scientific Reports, 7(1).

By: E. Kakaley  n, H. Wang n & G. LeBlanc n 

MeSH headings : Animals; Crustacea; Fatty Acids, Unsaturated / metabolism; Gene Expression; Models, Biological; Nuclear Receptor Coactivators / chemistry; Nuclear Receptor Coactivators / genetics; Nuclear Receptor Coactivators / metabolism; Protein Binding; Protein Multimerization; Protein Subunits / agonists; Protein Subunits / chemistry; Protein Subunits / genetics
topics (OpenAlex): Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities; Neurobiology and Insect Physiology Research; Reproductive biology and impacts on aquatic species
TL;DR: Results demonstrated that the Met subunit is highly dynamic in controlling the action of methyl farnesoate through temporal variation in its expression and availability for receptor assembly. (via Semantic Scholar)
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Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2006 article

A candidate juvenoid hormone receptor cis-element in the Daphnia magna hb2 hemoglobin gene promoter

Gorr, T. A., Rider, C. V., Wang, H. Y., Olmstead, A. W., & LeBlanc, G. A. (2006, January 7). Molecular and Cellular Endocrinology, Vol. 247, pp. 91–102.

By: T. Gorr *, C. Rider n, H. Wang n, A. Olmstead n & G. LeBlanc n 

author keywords: methyl farnesoate; juvenoid; crustacean; response element; sex determination
MeSH headings : Animals; Base Sequence; Cycloheximide / pharmacology; Daphnia / genetics; Daphnia / physiology; Fatty Acids, Unsaturated / metabolism; Hemoglobins / biosynthesis; Hemoglobins / genetics; Hemoglobins / physiology; Juvenile Hormones / metabolism; Molecular Sequence Data; Promoter Regions, Genetic; Pyridines / metabolism; RNA, Messenger / biosynthesis; Receptors, Cytoplasmic and Nuclear / genetics; Receptors, Cytoplasmic and Nuclear / metabolism; Response Elements; Signal Transduction
topics (OpenAlex): Neurobiology and Insect Physiology Research; Environmental Toxicology and Ecotoxicology; Invertebrate Immune Response Mechanisms
TL;DR: Induction of hb2 by juvenoids was not dependent upon the synthesis of secondary transcription factors that bound the JRE but was likely due to activation of the gene directly by the juvenoid-receptor complex. (via Semantic Scholar)
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UN Sustainable Development Goal Categories
2. Zero Hunger (Web of Science)
14. Life Below Water (OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2005 article

The screening of chemicals for juvenoid-related endocrine activity using the water flea Daphnia magna

Wang, H. Y., Olmstead, A. W., Li, H., & LeBlanc, G. A. (2005, July 20). Aquatic Toxicology, Vol. 74, pp. 193–204.

By: H. Wang n, A. Olmstead n, H. Li n & G. LeBlanc n 

author keywords: endocrine disruptors; screening; juvenoids; sex determination
MeSH headings : Animals; Benzhydryl Compounds; Daphnia / drug effects; Daphnia / metabolism; Ecdysteroids / metabolism; Ecdysteroids / pharmacology; Endocrine System / drug effects; Endpoint Determination / methods; Fatty Acids, Unsaturated / pharmacology; Female; Juvenile Hormones / agonists; Juvenile Hormones / antagonists & inhibitors; Juvenile Hormones / metabolism; Male; Methoprene / pharmacology; Pesticides / toxicity; Phenols / toxicity; Phytol / pharmacology; Pyridines / pharmacology; Reproducibility of Results; Sex Differentiation / drug effects; Toxicity Tests / methods; Tretinoin / pharmacology; United States; United States Environmental Protection Agency
topics (OpenAlex): Environmental Toxicology and Ecotoxicology; Neurobiology and Insect Physiology Research; Insect and Pesticide Research
TL;DR: Results demonstrate that an in vivo assay with a crustacean species customarily employed in toxicity testing can be used to effectively screen chemicals for juvenoid-modulating activity. (via Semantic Scholar)
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
2. Zero Hunger (Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

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