@article{strain_kelley_schultz-cherry_muse_koci_2008, title={Genomic analysis of closely related astroviruses}, volume={82}, ISSN={["0022-538X"]}, url={http://www.scopus.com/inward/record.url?eid=2-s2.0-43249085073&partnerID=MN8TOARS}, DOI={10.1128/JVI.01993-07}, abstractNote={ABSTRACT To understand astrovirus biology, it is essential to understand factors associated with its evolution. The current study reports the genomic sequences of nine novel turkey astrovirus (TAstV) type 2-like clinical isolates. This represents, to our knowledge, the largest genomic-length data set available for any one astrovirus type. The comparison of these TAstV sequences suggests that the TAstV species contains multiple subtypes and that recombination events have occurred across the astrovirus genome. In addition, the analysis of the capsid gene demonstrated evidence for both site-specific positive selection and purifying selection.}, number={10}, journal={JOURNAL OF VIROLOGY}, author={Strain, Errol and Kelley, Laura A. and Schultz-Cherry, Stacey and Muse, Spencer V. and Koci, Matthew D.}, year={2008}, month={May}, pages={5099–5103} } @article{strain_muse_2005, title={Positively selected sites in the Arabidopsis receptor-like kinase gene family}, volume={61}, ISSN={["1432-1432"]}, DOI={10.1007/s00239-004-0308-0}, abstractNote={We analyze members of the receptor-like kinase (RLK) gene family in Arabidopsis thaliana for positive selection. Likelihood analyses find evidence for positive selection in 12 of the 52 RLK family sequences groups. These 12 groups represent 97 of the 403 sequences analyzed. The majority of genes in groups subject to positive selection have not been functionally characterized, but sites under selection are predominantly located in the extracellular region. The pattern of selection in the extracellular leucine-rich repeat (LRR) motif of groups 14 and 51 is similar to previous studies where positively selected positions are located in a solvent exposed beta-strand that may determine disease specificity, raising the possibility that some RLK genes function in a similar role.}, number={3}, journal={JOURNAL OF MOLECULAR EVOLUTION}, author={Strain, E and Muse, SV}, year={2005}, month={Sep}, pages={325–332} }