@article{eads_hansen_oyegunwa_cecil_culver_scholle_petty_laster_2009, title={Terameprocol, a methylated derivative of nordihydroguaiaretic acid, inhibits production of prostaglandins and several key inflammatory cytokines and chemokines}, volume={6}, ISSN={["1476-9255"]}, DOI={10.1186/1476-9255-6-2}, abstractNote={Abstract}, journal={JOURNAL OF INFLAMMATION-LONDON}, author={Eads, D. and Hansen, R. L. and Oyegunwa, A. O. and Cecil, C. E. and Culver, C. A. and Scholle, F. and Petty, I. T. D. and Laster, S. M.}, year={2009}, month={Jan} }
 @article{culver_laster_2007, title={Adenovirus type 5 exerts multiple effects on the expression and activity of cytosolic phospholipase A(2), cyclooxygenase-2, and prostaglandin synthesis}, volume={179}, ISSN={["1550-6606"]}, DOI={10.4049/jimmunol.179.6.4170}, abstractNote={Abstract}, number={6}, journal={JOURNAL OF IMMUNOLOGY}, author={Culver, Carolyn A. and Laster, Scott M.}, year={2007}, month={Sep}, pages={4170–4179} }
 @article{maia_culver_laster_2006, title={Evidence against calcium as a mediator of mitochondrial dysfunction during apoptosis induced by arachidonic acid and other free fatty acids}, volume={177}, ISSN={["0022-1767"]}, DOI={10.4049/jimmunol.177.9.6398}, abstractNote={Abstract}, number={9}, journal={JOURNAL OF IMMUNOLOGY}, author={Maia, Rita C. and Culver, Carolyn A. and Laster, Scott M.}, year={2006}, month={Nov}, pages={6398–6404} }
 @article{culver_michalowski_maia_laster_2005, title={The anti-apoptotic effects of nordihydroguaiaretic acid: Inhibition of cPLA(2) activation during TNF-induced apoptosis arises from inhibition of calcium signaling}, volume={77}, ISSN={["1879-0631"]}, DOI={10.1016/j.lfs.2005.03.023}, abstractNote={Nordihydroguaiaretic acid (NDGA) is a plant lignan produced by Larrea tridentata, the creosote bush of the American southwest. In this report we examine the mechanism underlying the ability of NDGA to inhibit TNF-induced apoptosis. Our results show that NDGA blocks many key indicators of apoptosis. Caspase cleavage, mitochondrial inactivation, externalization of phosphatidyl serine, and (51)Cr-release were all blocked by low micromolar concentrations of NDGA. NDGA also inhibited the cPLA(2)-dependent release of (3)H-arachidonic acid. We investigated this activity and found that NDGA prevented the rise in intracellular calcium necessary for the apoptotic activation of cPLA(2). On the other hand, NDGA did not interfere with the TNF-induced phosphorylation of cPLA(2), indicating that NDGA does not block all TNF-dependent signaling. Finally, we asked whether the anti-apoptotic effect of NDGA could be attributed to its anti-oxidant activity. Comparison with the effects of butylated hydroxyanisole (BHA) did not completely support this hypothesis. While BHA strongly inhibited caspase activation and partially blocked the release of (51)Cr, it was unable to significantly block the calcium response or the release of (3)H-arachidonic acid associated with TNF-induced apoptosis. The anti-oxidant activity of NDGA may, therefore, explain some but not all of its anti-apoptotic activity.}, number={19}, journal={LIFE SCIENCES}, author={Culver, CA and Michalowski, SA and Maia, RC and Laster, SA}, year={2005}, month={Sep}, pages={2457–2470} }
 @article{culver_swaisgood_1989, title={CHANGES IN THE DIGESTIBILITY OF DRIED CASEIN AND GLUCOSE MIXTURES OCCURRING DURING STORAGE AT DIFFERENT TEMPERATURES AND WATER ACTIVITIES}, volume={72}, ISSN={["0022-0302"]}, DOI={10.3168/jds.S0022-0302(89)79442-X}, abstractNote={Abstract The digestibility of a dried, stored casein and glucose mixture was determined as a function of storage temperature, water activity, and carbohydrate:protein ratio by using the immobilized digestive enzyme assay. The sample contained either a 3:1 or 10:1 molar ratio of glucose:casein ɛ-amino groups and was stored for 30 d at either 30 or 60°C and at a water activity of .2 or .5. The extent of digestion was measured using two biodigesters, one containing immobilized pepsin and the other, immobilized trypsin, α -chymotrypsin, and intestinal mucosal peptidases. The biodigesters were operated in a fluidized-bed mode that permitted analysis of samples containing insoluble material. Losses in digestibility compared with unstored dried casein:glucose mixtures ranged from 18 to 88%. The largest changes in digestibility were observed upon changes in the water activity or temperature of storage. As would be expected from the extent of Maillard reactions, the greatest loss of digestibility occurred during storage of the high carbohydrate sample at the highest temperature and water activity.}, number={11}, journal={JOURNAL OF DAIRY SCIENCE}, author={CULVER, CA and SWAISGOOD, HE}, year={1989}, month={Nov}, pages={2916–2920} }