Laura M. Ellwein

Works (3)

Updated: July 5th, 2023 15:56

2009 journal article

ESTIMATION AND IDENTIFICATION OF PARAMETERS IN A LUMPED CEREBROVASCULAR MODEL

MATHEMATICAL BIOSCIENCES AND ENGINEERING, 6(1), 93–115.

By: S. Pope n, L. Ellwein*, C. Zapata, V. Novak*, C. Kelley*  & M. Olufsen n

author keywords: cardiovascular modeling; systemic resistance; cerebrovascular resistance; parameter estimation; sensitivity analysis; subset selection
MeSH headings : Adult; Aged; Blood Flow Velocity / physiology; Blood Pressure / physiology; Brain / blood supply; Brain / physiology; Cerebral Arteries / physiology; Cerebrovascular Circulation / physiology; Computer Simulation; Female; Humans; Male; Middle Aged; Models, Cardiovascular; Ventricular Function / physiology; Young Adult
TL;DR: The method discussed in this study provides a new methodology to extract clinical markers that cannot easily be assessed noninvasively by using nonlinear optimization combined with sensitivity analysis and subset selection. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2008 journal article

Sensitivity analysis and model assessment: Mathematical models for arterial blood flow and blood pressure

CARDIOVASCULAR ENGINEERING, 8(2), 94–108.

By: L. Ellwein n, H. Tran n , C. Zapata n, V. Novak n & M. Olufsen n

author keywords: cardiovascular modeling; sensitivity analysis; model reduction; parameter estimation
MeSH headings : Algorithms; Arteries / physiology; Blood Flow Velocity / physiology; Blood Pressure / physiology; Computer Simulation; Diagnosis, Computer-Assisted / methods; Models, Cardiovascular; Posture / physiology; Reproducibility of Results; Sensitivity and Specificity
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2005 journal article

Blood pressure and blood flow variation during postural change from sitting to standing: model development and validation

JOURNAL OF APPLIED PHYSIOLOGY, 99(4), 1523–1537.

By: M. Olufsen*, J. Ottesen, H. Tran* , L. Ellwein*, L. Lipsitz & V. Novak

author keywords: cardiovascular system; mathematical modeling; cerebral blood flow; gravitational effect; autonomic regulation; cerebral autoregulation
MeSH headings : Autonomic Nervous System / physiology; Blood Circulation / physiology; Blood Pressure / physiology; Cerebrovascular Circulation / physiology; Homeostasis; Humans; Linear Models; Models, Cardiovascular; Posture / physiology
TL;DR: A mathematical model is presented that can predict dynamic changes in beat-to-beat arterial blood pressure and middle cerebral artery blood flow velocity during postural change from sitting to standing and is in agreement with physiological data from a young subject during postures change from Sitting to standing. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

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