Ren-Hua Chung

Works (6)

Updated: July 19th, 2023 21:15

2018 article

Genetic loci determining total immunoglobulin E levels from birth through adulthood

Yao, T. C., Chung, R. H., Lin, C. Y., Tsai, P. C., Chang, W. C., Yeh, K. W., … Huang, J. L. (2018, October 31). Allergy, Vol. 74, pp. 621–625.

By: T. Yao *, R. Chung*, C. Lin *, P. Tsai*, W. Chang *, K. Yeh *, M. Tsai *, S. Liao* ...

MeSH headings : Age Factors; Female; Genetic Loci; Genetic Predisposition to Disease; Genome-Wide Association Study; Humans; Immunoglobulin E / blood; Immunoglobulin E / immunology; Pregnancy
topics (OpenAlex): Immunodeficiency and Autoimmune Disorders; Immune Cell Function and Interaction; T-cell and B-cell Immunology
TL;DR: The whole metagenome profiling reveals skin microbiome‐dependent susceptibility to atopic dermatitis flare, and deep sequencing transcriptome analysis of murine wound healing: effects of a multicomponent, Multitarget Natural Product Therapy‐Tr14. (via Semantic Scholar)
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Sources: Web Of Science, NC State University Libraries
Added: March 11, 2019

2008 article

X‐LRT: a likelihood approach to estimate genetic risks and test association with X‐linked markers using a case‐parents design

Zhang, L., Martin, E. R., Chung, R. H., Li, Y. J., & Morris, R. W. (2008, February 15). Genetic Epidemiology.

By: L. Zhang n, E. Martin*, R. Chung*, Y. Li * & R. Morris *

author keywords: sex linked; maximum-likelihood estimation; confidence interval; hypothesis test; family-based design
MeSH headings : Algorithms; Biometry; Computer Simulation; Confidence Intervals; Epidemiologic Methods; Female; Genes, X-Linked; Genetic Diseases, X-Linked / epidemiology; Genetic Diseases, X-Linked / genetics; Genetic Markers; Haplotypes; Humans; Likelihood Functions; Male; Models, Genetic; Monoamine Oxidase / genetics; Parents; Parkinson Disease / enzymology; Parkinson Disease / genetics; Penetrance; Risk Factors; Siblings
topics (OpenAlex): Genetic Associations and Epidemiology; T-cell and Retrovirus Studies; Nuclear Receptors and Signaling
TL;DR: A likelihood approach to estimate disease‐related marker relative risks and test genotype association using a case‐parents design and shows how efficiency with missing parental information can be improved with additional sibling genotype information. (via Semantic Scholar)
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Source: Web Of Science
Added: August 6, 2018

2006 article

Interpretation of simultaneous linkage and family‐based association tests in genome screens

Chung, R. H., Hauser, E. R., & Martin, E. R. (2006, November 22). Genetic Epidemiology.

By: R. Chung n, E. Hauser * & E. Martin *

author keywords: linkage analysis; family-based association analysis; correlation
MeSH headings : Alleles; Chromosome Mapping; Computer Simulation; Female; Genetic Markers; Genome, Human; Genotype; Humans; Linkage Disequilibrium / genetics; Male; Models, Genetic; Nuclear Family; Pedigree; Prevalence; Siblings; Statistical Distributions
topics (OpenAlex): Genetic Associations and Epidemiology; Bioinformatics and Genomic Networks; Epigenetics and DNA Methylation
TL;DR: It is concluded that when linkage and association tests are applied in the same data, the type I error rate of neither test will be affected and that power can be increased by applying tests conditionally. (via Semantic Scholar)
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Source: Web Of Science
Added: August 6, 2018

2006 article

The APL Test: Extension to General Nuclear Families and Haplotypes and Examination of Its Robustness

Chung, R.-H., Hauser, E. R., & Martin, E. R. (2006, January 1). Human Heredity.

By: R. Chung n, E. Hauser * & E. Martin *

author keywords: family-based association; linkage disequilibrium; haplotype analysis; rare alleles and rare haplotypes; Hardy-Weinberg disequilibrium
MeSH headings : Computer Simulation; Data Interpretation, Statistical; Gene Frequency; Haplotypes; Humans; Linkage Disequilibrium; Models, Genetic
topics (OpenAlex): Genetic Associations and Epidemiology; Statistical Methods in Clinical Trials; Genetics and Plant Breeding
TL;DR: This work presents a generalization of the APL model and examination of its robustness under a variety of non-standard scenarios, and evaluated general guidelines for the validity of APL with rare alleles and rare haplotypes. (via Semantic Scholar)
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Source: Web Of Science
Added: August 6, 2018

2006 article

X-APL: An Improved Family-Based Test of Association in the Presence of Linkage for the X Chromosome

Chung, R.-H., Morris, R. W., Zhang, L., Li, Y.-J., & Martin, E. R. (2006, December 12). The American Journal of Human Genetics.

By: R. Chung n, R. Morris, L. Zhang n, Y. Li  n & E. Martin  n

MeSH headings : Chromosomes, Human, X / genetics; Family; Female; Genetic Diseases, X-Linked / genetics; Genetic Markers; Humans; Linkage Disequilibrium; Male; Monoamine Oxidase / genetics; Parkinson Disease / genetics; Pedigree; Siblings
topics (OpenAlex): Genetic Associations and Epidemiology; Genetics and Neurodevelopmental Disorders; Nuclear Receptors and Signaling
TL;DR: A novel family-based test of association, X-APL, a modification of the test for association in the presence of linkage (APL) test that can use singleton or multiplex families and properly infers missing parental genotypes in linkage regions by considering identity-by-descent parameters for affected siblings. (via Semantic Scholar)
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Source: Web Of Science
Added: August 6, 2018

2005 article

Interaction between the  -T catenin gene (VR22) and APOE in Alzheimer's disease

Martin, E. R., Bronson, P. G., Li, Y. J., Wall, N., Chung, R. H., Schmechel, D. E., … Pericak-Vance, M. A. (2005, September 30). Journal of Medical Genetics.

By: E. Martin *, P. Bronson *, Y. Li *, N. Wall *, R. Chung n, D. Schmechel*, G. Small *, P. Xu * ...

MeSH headings : Aged; Aged, 80 and over; Alzheimer Disease / genetics; Apolipoproteins E / genetics; Female; Genetic Predisposition to Disease; Humans; Linkage Disequilibrium; Male; Polymorphism, Genetic; Polymorphism, Single Nucleotide; alpha Catenin / genetics
topics (OpenAlex): Alzheimer's disease research and treatments; 14-3-3 protein interactions; Nuclear Receptors and Signaling
TL;DR: This study suggests that VR22 or a nearby gene influences susceptibility to Alzheimer’s disease, and the effect is dependent on APOE status. (via Semantic Scholar)
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3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

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