Works (7)
Updated: August 16th, 2024 13:38
2004 journal article
Pharmacokinetics of sulfadimethoxine and ormetoprim in a 5 : 1 ratio following intraperitoneal and oral administration, in the hybrid striped bass (Morone chrysops x Morone saxitalis)
JOURNAL OF VETERINARY PHARMACOLOGY AND THERAPEUTICS, 27(1), 1–6.
MeSH headings : Administration, Oral; Aeromonas / drug effects; Animals; Anti-Infective Agents / administration & dosage; Anti-Infective Agents / pharmacokinetics; Anti-Infective Agents / pharmacology; Area Under Curve; Bass / metabolism; Crosses, Genetic; Drug Therapy, Combination; Edwardsiella / drug effects; Escherichia coli / drug effects; Injections, Intraperitoneal / veterinary; Microbial Sensitivity Tests; Pseudomonas / drug effects; Pyrimidines / administration & dosage; Pyrimidines / pharmacokinetics; Pyrimidines / pharmacology; Sulfadimethoxine / administration & dosage; Sulfadimethoxine / pharmacokinetics; Sulfadimethoxine / pharmacology; Yersinia / drug effects
TL;DR:
The single 50 mg/kg oral dose of the 5:1 combination of sulfadimethoxine and ormetoprim appears to provide plasma concentrations high enough to inhibit the growth of Yersinia ruckeri, Edwardsiella tarda, and Escherichia coli.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018
2000 journal article
Cloning of canine cytochrome P450 2E1 CDNA: identification and characterization of two variant alleles
Drug Metabolism and Disposition, 28(8), 981–986.
Source: NC State University Libraries
Added: August 6, 2018
1998 journal article
Isolation of a new canine cytochrome P450 cDNA from the cytochrome P450 2C subfamily (CYP2C41) and evidence for polymorphic differences in its expression
Drug Metabolism and Disposition, 26(3), 278–283.
Source: NC State University Libraries
Added: August 6, 2018
1997 journal article
Determination of concentration of albendazole sulfoxide in plasma and uterine fluid of heifers
American Journal of Veterinary Research, 58(1), 62–65.
Source: NC State University Libraries
Added: August 6, 2018
1997 journal article
Pharmacokinetic-pharmacodynamic relations of losartan and EXP3174 in a porcine animal model
JOURNAL OF CARDIOVASCULAR PHARMACOLOGY, 30(5), 583–590.
author keywords: angiotensin; losartan; EXP3174; pharmacokinetics; pharmacodynamics; pig
MeSH headings : Angiotensin II / administration & dosage; Animals; Anti-Arrhythmia Agents / pharmacokinetics; Anti-Arrhythmia Agents / pharmacology; Antihypertensive Agents / pharmacokinetics; Antihypertensive Agents / pharmacology; Area Under Curve; Blood Pressure / drug effects; Disease Models, Animal; Half-Life; Hypertension / chemically induced; Hypertension / drug therapy; Imidazoles / pharmacokinetics; Imidazoles / pharmacology; Infusions, Intravenous; Losartan / pharmacokinetics; Losartan / pharmacology; Receptors, Angiotensin / drug effects; Swine; Tetrazoles / pharmacokinetics; Tetrazoles / pharmacology
TL;DR:
The pharmacokinetics of losartan and EXP3174, an active metabolite ofLosartan, were evaluated in the anesthetized pig after both a single intravenous dose and during constant intravenous infusion to determine the degree of inhibition of angiotensin II-induced increase in the diastolic pressure.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
1986 conference paper
Effects of disease on drug binding to serum proteins
Comparative veterinary pharmacology, toxicology, and therapy: proceedings of the 3rd Congress of the European Association for Veterinary Pharmacology and Toxicology, August 25-29, 1985, Ghent, Belgium, 3, 407–414.
TL;DR:
The preliminary investigations showed that, as in humans, the binding of organic bases is increased in diseases associated with stress and inflammation, and that larger doses of basic drugs may be required if the patient has a concurrent disease associated with inflammation.
(via Semantic Scholar)
Source: NC State University Libraries
Added: August 6, 2018
1985 journal article
Pharmacokinetics of digoxin in sheep: Limitations of the use of biological half life for interspecies extrapolation
American Journal of Veterinary Research, 46, 470–472.
Source: NC State University Libraries
Added: August 6, 2018
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