Works (32)

2015 journal article

Optically triggered immune response through photocaged oligonucleotides

TETRAHEDRON LETTERS, 56(23), 3639–3642.

By: J. Govan, D. Young, M. Lively* & A. Deiters

author keywords: Oligonucleotide synthesis; Light-activation; Photocaged nucleotides; Immune response; Toll-like receptors
Source: Web Of Science
Added: August 6, 2018

2011 journal article

Heterotaxin: A TGF-beta Signaling Inhibitor Identified in a Multi-Phenotype Profiling Screen in Xenopus Embryos

CHEMISTRY & BIOLOGY, 18(2), 252–263.

By: M. Dush n, A. McIver, M. Parr n, D. Young, J. Fisher, D. Newman, P. Sannes, M. Hauck, A. Deiters, N. Nascone-Yoder

Source: Web Of Science
Added: August 6, 2018

2011 journal article

Light Regulation of Protein Dimerization and Kinase Activity in Living Cells Using Photocaged Rapamycin and Engineered FKBP

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 133(3), 420–423.

Source: Web Of Science
Added: August 6, 2018

2010 journal article

Activation and Deactivation of DNAzyme and Antisense Function with Light for the Photochemical Regulation of Gene Expression in Mammalian Cells

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 132(17), 6183–6193.

By: D. Young, M. Lively* & A. Deiters

Source: Web Of Science
Added: August 6, 2018

2010 journal article

Photocaged T7 RNA Polymerase for the Light Activation of Transcription and Gene Function in Pro- and Eukaryotic Cells

CHEMBIOCHEM, 11(7), 972–977.

By: C. Chou, D. Young & A. Deiters

author keywords: amino acids; caged proteins; light activation; polymerases; RNA
Source: Web Of Science
Added: August 6, 2018

2010 journal article

Site-Specific Incorporation of Fluorotyrosines into Proteins in Escherichia coli by Photochemical Disguise

BIOCHEMISTRY, 49(8), 1557–1559.

By: B. Wilkins*, S. Marionni*, D. Young, J. Liu*, Y. Wang*, M. Di Salvo*, A. Deiters, T. Cropp*

Source: Web Of Science
Added: August 6, 2018

2010 journal article

Small Molecule Modifiers of MicroRNA miR-122 Function for the Treatment of Hepatitis C Virus Infection and Hepatocellular Carcinoma

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 132(23), 7976–7981.

Source: Web Of Science
Added: August 6, 2018

2009 journal article

A Light-Activated DNA Polymerase

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 48(32), 5950–5953.

By: C. Chou, D. Young & A. Deiters

author keywords: DNA polymerases; mutagenesis; non-natural amino acids; photoactivation; polymerase chain reaction
Source: Web Of Science
Added: August 6, 2018

2009 journal article

Development of a Robust and High Throughput Method for Profiling N-Linked Glycans Derived from Plasma Glycoproteins by NanoLC-FTICR Mass Spectrometry

JOURNAL OF PROTEOME RESEARCH, 8(7), 3764–3770.

By: M. Bereman, D. Young, A. Deiters & D. Muddiman

Sources: Web Of Science, ORCID
Added: August 6, 2018

2009 journal article

Light-Activated Cre Recombinase as a Tool for the Spatial and Temporal Control of Gene Function in Mammalian Cells

ACS CHEMICAL BIOLOGY, 4(6), 441–445.

By: W. Edwards, D. Young & A. Deiters

Source: Web Of Science
Added: August 6, 2018

2009 journal article

Light-activation of gene function in mammalian cells via ribozymes

Chem. Commun., (5), 568–570.

By: D. Young, R. Garner, J. Yoder & A. Deiters

Sources: Web Of Science, ORCID, Crossref
Added: August 6, 2018

2009 journal article

Open-Vessel Microwave-Mediated [2+2+2]-Cyclotrimerization Reactions

SYNTHESIS-STUTTGART, (22), 3785–3790.

By: D. Young, J. Teske & A. Deiters

author keywords: [2+2+2] cyclotrimerization; alkynes; microwave; bicyclic compounds; transition metal catalysis
Source: Web Of Science
Added: August 6, 2018

2009 journal article

Photochemical Regulation of Restriction Endonuclease Activity

CHEMBIOCHEM, 10(10), 1612–1616.

By: D. Young, J. Govan, M. Lively* & A. Deiters

author keywords: cage compounds; DNA cleavage; DNA enzymes; photochemistry
Source: Web Of Science
Added: August 6, 2018

2009 journal article

Restriction enzyme-free mutagenesis via the light regulation of DNA polymerization

Nucleic Acids Research, 37(8).

By: D. Young, H. Lusic, M. Lively & A. Deiters

Source: NC State University Libraries
Added: August 6, 2018

2009 journal article

The effect of microwave irradiation on DNA hybridization

ORGANIC & BIOMOLECULAR CHEMISTRY, 7(12), 2506–2508.

By: W. Edwards, D. Young & A. Deiters

Source: Web Of Science
Added: August 6, 2018

2008 journal article

A general approach to triphenylenes and azatriphenylenes: total synthesis of dehydrotylophorine and tylophorine

CHEMICAL COMMUNICATIONS, (39), 4750–4752.

By: A. McIver, D. Young & A. Deiters

Source: Web Of Science
Added: August 6, 2018

2008 journal article

Gene Silencing in Mammalian Cells with Light-Activated Antisense Agents

ChemBioChem, 9(18), 2937–2940.

By: D. Young, H. Lusic, M. Lively*, J. Yoder & A. Deiters

author keywords: Antisense agents; caged compounds; DNA; gene regulation; RNA
Sources: Web Of Science, ORCID, Crossref
Added: August 6, 2018

2008 journal article

Light-regulated RNA-small molecule interactions

CHEMBIOCHEM, 9(8), 1225–1228.

By: D. Young & A. Deiters

author keywords: aptamer; light; riboswitch; RNA; spiropyran
Source: Web Of Science
Added: August 6, 2018

2008 journal article

Light-triggered polymerase chain reaction

CHEMICAL COMMUNICATIONS, (4), 462–464.

By: D. Young, W. Edwards n, H. Lusic, M. Lively* & A. Deiters

Source: Web Of Science
Added: August 6, 2018

2008 journal article

Microwave activation of enzymatic catalysis

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 130(31), 10048-+.

By: D. Young, J. Nichols, R. Kelly & A. Deiters

Sources: Web Of Science, ORCID
Added: August 6, 2018

2008 journal article

Microwave-assisted synthesis of unnatural amino acids

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 18(20), 5478–5480.

By: D. Young, J. Torres-Kolbus n & A. Deiters

author keywords: microwave; microwave synthesis; amino acid; unnatural amino acid; peptide synthesis; protein synthesis; unnatural amino acid; mutagenesis
Source: Web Of Science
Added: August 6, 2018

2008 journal article

Small-molecule inhibitors of microRNA miR-21 function

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 47(39), 7482–7484.

By: K. Gumireddy*, D. Young, X. Xiong n, J. Hogenesch*, Q. Huang* & A. Deiters

author keywords: antitumor agents; cell-based assays; inhibitors; medicinal chemistry; microRNA
Source: Web Of Science
Added: August 6, 2018

2008 journal article

Synthesis of Anthracene and Azaanthracene Fluorophores via [2+2+2] Cyclotrimerization Reactions

ORGANIC LETTERS, 10(20), 4661–4664.

Source: Web Of Science
Added: August 6, 2018

2007 journal article

A general approach to chemo- and regioselective cyclotrimerization reactions

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 46(27), 5187–5190.

By: D. Young & A. Deiters

author keywords: cycloaddition; heterocycles; microwave synthesis; solid-phase synthesis; transition metals
Source: Web Of Science
Added: August 6, 2018

2007 journal article

Microwave-assisted solid-supported alkyne cyclotrimerization reactions for combinatorial chemistry

JOURNAL OF COMBINATORIAL CHEMISTRY, 9(5), 735–738.

By: D. Young, L. Sripada & A. Deiters

Source: Web Of Science
Added: August 6, 2018

2007 journal article

Photochemical DNA activation

ORGANIC LETTERS, 9(10), 1903–1906.

By: H. Lusic, D. Young, M. Lively* & A. Deiters

Source: Web Of Science
Added: August 6, 2018

2007 journal article

Photochemical activation of protein expression in bacterial cells

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 46(23), 4290–4292.

By: D. Young & A. Deiters

author keywords: bacterial cells; caged compounds; gene expression; photochemistry; proteins
Source: Web Of Science
Added: August 6, 2018

2007 journal article

Photochemical control of biological processes

ORGANIC & BIOMOLECULAR CHEMISTRY, 5(7), 999–1005.

By: D. Young & A. Deiters

Source: Web Of Science
Added: August 6, 2018

2007 journal article

Synthesis of indanones via solid-supported [2+2+2] cyclotrimerization

JOURNAL OF ORGANIC CHEMISTRY, 72(20), 7801–7804.

By: R. Senaiar, J. Teske, D. Young & A. Deiters

Source: Web Of Science
Added: August 6, 2018

2006 journal article

Photochemical hammerhead ribozyme activation

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 16(10), 2658–2661.

By: D. Young & A. Deiters

author keywords: caged compounds; genomics; photochemistry; ribozymes; RNA
Source: Web Of Science
Added: August 6, 2018

2006 journal article

Pyridines via solid-supported [2+2+2] cyclotrimerization

Chemical Communications (Cambridge, England), (12), 1313–1315.

By: R. Senaiar, D. Young & A. Deiters

Source: NC State University Libraries
Added: August 6, 2018

2006 journal article

Solid-supported [2+2+2] cyclotrimerizations

CHEMISTRY-A EUROPEAN JOURNAL, 12(21), 5563–5568.

By: D. Young, R. Senaiar & A. Deiters

author keywords: combinatorial chemistry; cyclotrimerization; homogeneous catalysis; solid-phase synthesis
Source: Web Of Science
Added: August 6, 2018