Douglas D. Young

Optically triggered immune response through photocaged oligonucleotides

TETRAHEDRON LETTERS, 56(23), 3639–3642.

Heterotaxin: A TGF-beta Signaling Inhibitor Identified in a Multi-Phenotype Profiling Screen in Xenopus Embryos

CHEMISTRY & BIOLOGY, 18(2), 252–263.

Light Regulation of Protein Dimerization and Kinase Activity in Living Cells Using Photocaged Rapamycin and Engineered FKBP

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 133(3), 420–423.

Activation and Deactivation of DNAzyme and Antisense Function with Light for the Photochemical Regulation of Gene Expression in Mammalian Cells

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 132(17), 6183–6193.

Photocaged T7 RNA Polymerase for the Light Activation of Transcription and Gene Function in Pro- and Eukaryotic Cells

CHEMBIOCHEM, 11(7), 972–977.

Site-Specific Incorporation of Fluorotyrosines into Proteins in Escherichia coli by Photochemical Disguise

BIOCHEMISTRY, 49(8), 1557–1559.

Small Molecule Modifiers of MicroRNA miR-122 Function for the Treatment of Hepatitis C Virus Infection and Hepatocellular Carcinoma

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 132(23), 7976–7981.

A Light-Activated DNA Polymerase

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 48(32), 5950–5953.

Development of a Robust and High Throughput Method for Profiling N-Linked Glycans Derived from Plasma Glycoproteins by NanoLC-FTICR Mass Spectrometry

JOURNAL OF PROTEOME RESEARCH, 8(7), 3764–3770.

Light-Activated Cre Recombinase as a Tool for the Spatial and Temporal Control of Gene Function in Mammalian Cells

ACS CHEMICAL BIOLOGY, 4(6), 441–445.

Light-activation of gene function in mammalian cells via ribozymes

Chem. Commun., (5), 568–570.

Open-Vessel Microwave-Mediated [2+2+2]-Cyclotrimerization Reactions

SYNTHESIS-STUTTGART, (22), 3785–3790.

Photochemical Regulation of Restriction Endonuclease Activity

CHEMBIOCHEM, 10(10), 1612–1616.

Restriction enzyme-free mutagenesis via the light regulation of DNA polymerization

Nucleic Acids Research, 37(8).

The effect of microwave irradiation on DNA hybridization

ORGANIC & BIOMOLECULAR CHEMISTRY, 7(12), 2506–2508.

A general approach to triphenylenes and azatriphenylenes: total synthesis of dehydrotylophorine and tylophorine

CHEMICAL COMMUNICATIONS, (39), 4750–4752.

Gene Silencing in Mammalian Cells with Light-Activated Antisense Agents

ChemBioChem, 9(18), 2937–2940.

Light-regulated RNA-small molecule interactions

CHEMBIOCHEM, 9(8), 1225–1228.

Light-triggered polymerase chain reaction

CHEMICAL COMMUNICATIONS, (4), 462–464.

Microwave activation of enzymatic catalysis

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 130(31), 10048-+.

Microwave-assisted synthesis of unnatural amino acids

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 18(20), 5478–5480.

Small-molecule inhibitors of microRNA miR-21 function

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 47(39), 7482–7484.

Synthesis of Anthracene and Azaanthracene Fluorophores via [2+2+2] Cyclotrimerization Reactions

ORGANIC LETTERS, 10(20), 4661–4664.

A general approach to chemo- and regioselective cyclotrimerization reactions

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 46(27), 5187–5190.

Microwave-assisted solid-supported alkyne cyclotrimerization reactions for combinatorial chemistry

JOURNAL OF COMBINATORIAL CHEMISTRY, 9(5), 735–738.

Photochemical DNA activation

ORGANIC LETTERS, 9(10), 1903–1906.

Photochemical activation of protein expression in bacterial cells

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 46(23), 4290–4292.

Photochemical control of biological processes

ORGANIC & BIOMOLECULAR CHEMISTRY, 5(7), 999–1005.

Synthesis of indanones via solid-supported [2+2+2] cyclotrimerization

JOURNAL OF ORGANIC CHEMISTRY, 72(20), 7801–7804.

Photochemical hammerhead ribozyme activation

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 16(10), 2658–2661.

Pyridines via solid-supported [2+2+2] cyclotrimerization

Chemical Communications (Cambridge, England), (12), 1313–1315.

Solid-supported [2+2+2] cyclotrimerizations

CHEMISTRY-A EUROPEAN JOURNAL, 12(21), 5563–5568.