Douglas D. Young

Govan, J. M., Young, D. D., Lively, M. O., & Deiters, A. (2015). Optically triggered immune response through photocaged oligonucleotides. TETRAHEDRON LETTERS, 56(23), 3639–3642. https://doi.org/10.1016/j.tetlet.2015.01.165

Dush, M. K., McIver, A. L., Parr, M. A., Young, D. D., Fisher, J., Newman, D. R., … Nascone-Yoder, N. (2011). Heterotaxin: A TGF-beta Signaling Inhibitor Identified in a Multi-Phenotype Profiling Screen in Xenopus Embryos. CHEMISTRY & BIOLOGY, 18(2), 252–263. https://doi.org/10.1016/j.chembiol.2010.12.008

Karginov, A. V., Zou, Y., Shirvanyants, D., Kota, P., Dokholyan, N. V., Young, D. D., … Deiters, A. (2011). Light Regulation of Protein Dimerization and Kinase Activity in Living Cells Using Photocaged Rapamycin and Engineered FKBP. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 133(3), 420–423. https://doi.org/10.1021/ja109630v

Young, D. D., Lively, M. O., & Deiters, A. (2010). Activation and Deactivation of DNAzyme and Antisense Function with Light for the Photochemical Regulation of Gene Expression in Mammalian Cells. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 132(17), 6183–6193. https://doi.org/10.1021/ja100710j

Chou, C., Young, D. D., & Deiters, A. (2010). Photocaged T7 RNA Polymerase for the Light Activation of Transcription and Gene Function in Pro- and Eukaryotic Cells. CHEMBIOCHEM, 11(7), 972–977. https://doi.org/10.1002/cbic.201000041

Wilkins, B. J., Marionni, S., Young, D. D., Liu, J., Wang, Y., Di Salvo, M. L., … Cropp, T. A. (2010). Site-Specific Incorporation of Fluorotyrosines into Proteins in Escherichia coli by Photochemical Disguise. BIOCHEMISTRY, 49(8), 1557–1559. https://doi.org/10.1021/bi100013s

Young, D. D., Connelly, C. M., Grohmann, C., & Deiters, A. (2010). Small Molecule Modifiers of MicroRNA miR-122 Function for the Treatment of Hepatitis C Virus Infection and Hepatocellular Carcinoma. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 132(23), 7976–7981. https://doi.org/10.1021/ja910275u

Chou, C., Young, D. D., & Deiters, A. (2009). A Light-Activated DNA Polymerase. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 48(32), 5950–5953. https://doi.org/10.1002/anie.200901115

Bereman, M. S., Young, D. D., Deiters, A., & Muddiman, D. C. (2009). Development of a Robust and High Throughput Method for Profiling N-Linked Glycans Derived from Plasma Glycoproteins by NanoLC-FTICR Mass Spectrometry. JOURNAL OF PROTEOME RESEARCH, 8(7), 3764–3770. https://doi.org/10.1021/pr9002323

Edwards, W. F., Young, D. D., & Deiters, A. (2009). Light-Activated Cre Recombinase as a Tool for the Spatial and Temporal Control of Gene Function in Mammalian Cells. ACS CHEMICAL BIOLOGY, 4(6), 441–445. https://doi.org/10.1021/cb900041s

Young, D. D., Garner, R. A., Yoder, J. A., & Deiters, A. (2009). Light-activation of gene function in mammalian cells via ribozymes. Chem. Commun., (5), 568–570. https://doi.org/10.1039/b819375d

Young, D. D., Teske, J. A., & Deiters, A. (2009). Open-Vessel Microwave-Mediated [2+2+2]-Cyclotrimerization Reactions. SYNTHESIS-STUTTGART, (22), 3785–3790. https://doi.org/10.1055/s-0029-1218149

Young, D. D., Govan, J. M., Lively, M. O., & Deiters, A. (2009). Photochemical Regulation of Restriction Endonuclease Activity. CHEMBIOCHEM, 10(10), 1612–1616. https://doi.org/10.1002/cbic.200900090

Young, D. D., Lusic, H., Lively, M. O., & Deiters, A. (2009). Restriction enzyme-free mutagenesis via the light regulation of DNA polymerization. Nucleic Acids Research, 37(8).

Edwards, W. F., Young, D. D., & Deiters, A. (2009). The effect of microwave irradiation on DNA hybridization. ORGANIC & BIOMOLECULAR CHEMISTRY, 7(12), 2506–2508. https://doi.org/10.1039/b903609a

McIver, A., Young, D. D., & Deiters, A. (2008). A general approach to triphenylenes and azatriphenylenes: total synthesis of dehydrotylophorine and tylophorine. CHEMICAL COMMUNICATIONS, (39), 4750–4752. https://doi.org/10.1039/b811068a

Young, D. D., Lusic, H., Lively, M. O., Yoder, J. A., & Deiters, A. (2008). Gene Silencing in Mammalian Cells with Light-Activated Antisense Agents. ChemBioChem, 9(18), 2937–2940. https://doi.org/10.1002/cbic.200800627

Young, D. D., & Deiters, A. (2008). Light-regulated RNA-small molecule interactions. CHEMBIOCHEM, 9(8), 1225–1228. https://doi.org/10.1002/cbic.200800051

Young, D. D., Edwards, W. F., Lusic, H., Lively, M. O., & Deiters, A. (2008). Light-triggered polymerase chain reaction. CHEMICAL COMMUNICATIONS, (4), 462–464. https://doi.org/10.1039/b715152g

Young, D. D., Nichols, J., Kelly, R. M., & Deiters, A. (2008). Microwave activation of enzymatic catalysis. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 130(31), 10048-+. https://doi.org/10.1021/ja802404g

Young, D. D., Torres-Kolbus, J., & Deiters, A. (2008). Microwave-assisted synthesis of unnatural amino acids. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 18(20), 5478–5480. https://doi.org/10.1016/j.bmcl.2008.09.025

Gumireddy, K., Young, D. D., Xiong, X., Hogenesch, J. B., Huang, Q., & Deiters, A. (2008). Small-molecule inhibitors of microRNA miR-21 function. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 47(39), 7482–7484. https://doi.org/10.1002/anie.200801555

Zou, Y., Young, D. D., Cruz-Montanez, A., & Deiters, A. (2008). Synthesis of Anthracene and Azaanthracene Fluorophores via [2+2+2] Cyclotrimerization Reactions. ORGANIC LETTERS, 10(20), 4661–4664. https://doi.org/10.1021/ol8019549

Young, D. D., & Deiters, A. (2007). A general approach to chemo- and regioselective cyclotrimerization reactions. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 46(27), 5187–5190. https://doi.org/10.1002/anie.200700802

Young, D. D., Sripada, L., & Deiters, A. (2007). Microwave-assisted solid-supported alkyne cyclotrimerization reactions for combinatorial chemistry. JOURNAL OF COMBINATORIAL CHEMISTRY, 9(5), 735–738. https://doi.org/10.1021/cc070068b

Lusic, H., Young, D. D., Lively, M. O., & Deiters, A. (2007). Photochemical DNA activation. ORGANIC LETTERS, 9(10), 1903–1906. https://doi.org/10.1021/ol070455u

Young, D. D., & Deiters, A. (2007). Photochemical activation of protein expression in bacterial cells. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 46(23), 4290–4292. https://doi.org/10.1002/anie.200700057

Young, D. D., & Deiters, A. (2007). Photochemical control of biological processes. ORGANIC & BIOMOLECULAR CHEMISTRY, 5(7), 999–1005. https://doi.org/10.1039/b616410m

Senaiar, R. S., Teske, J. A., Young, D. D., & Deiters, A. (2007). Synthesis of indanones via solid-supported [2+2+2] cyclotrimerization. JOURNAL OF ORGANIC CHEMISTRY, 72(20), 7801–7804. https://doi.org/10.1021/jo7013565

Young, D. D., & Deiters, A. (2006). Photochemical hammerhead ribozyme activation. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 16(10), 2658–2661. https://doi.org/10.1016/j.bmcl.2006.02.034

Senaiar, R. S., Young, D. D., & Deiters, A. (2006). Pyridines via solid-supported [2+2+2] cyclotrimerization. Chemical Communications (Cambridge, England), (12), 1313–1315. https://doi.org/10.1039/b515901f

Young, D. D., Senaiar, R. S., & Deiters, A. (2006). Solid-supported [2+2+2] cyclotrimerizations. CHEMISTRY-A EUROPEAN JOURNAL, 12(21), 5563–5568. https://doi.org/10.1002/chem.200501360