Qiang Liu

Works (6)

Updated: July 5th, 2023 15:56

2015 journal article

Matrix-enhanced surface-assisted laser desorption/ionization mass spectrometry (ME-SALDI-MS) for mass spectrometry imaging of small molecules

Mass Spectrometry Imaging of Small Molecules, 1203, 175–184.

By: V. Brown, Q. Liu & L. He

Source: NC State University Libraries
Added: August 6, 2018

2011 journal article

Synthesis of the Pyridine Core of Cyclothiazomycin

ORGANIC LETTERS, 13(16), 4352–4355.

By: Y. Zou n, Q. Liu  n & A. Deiters n

MeSH headings : Anti-Bacterial Agents / chemical synthesis; Molecular Structure; Peptides, Cyclic / chemistry; Pyridines / chemical synthesis; Thiazoles / chemistry
TL;DR: A highly convergent synthesis of the pyridine core of the thiopeptide antibiotic cyclothiazomycin has been developed based on a [2-2+2] cyclotrimerization key step. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2008 journal article

Metabolite Imaging Using Matrix-Enhanced Surface-Assisted Laser Desorption/Ionization Mass Spectrometry (ME-SALDI-MS)

JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY, 20(1), 80–88.

By: Q. Liu n, Y. Xiao n, C. Pagan-Miranda n, Y. Chiu n & L. He n

MeSH headings : Animals; Brain Chemistry; Cerebellum / chemistry; Cerebrum / chemistry; Diagnostic Imaging / methods; Dimyristoylphosphatidylcholine / chemistry; Female; Mice; Myocardium / chemistry; Sensitivity and Specificity; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization / methods
TL;DR: ME-SALDI combines the strengths of traditional matrix-assisted laser desorption/ionization (MALDI) and SALDI and enables successful MS imaging of low-mass species with improved detection sensitivity. (via Semantic Scholar)
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Source: Web Of Science
Added: August 6, 2018

2007 journal article

Mass spectrometry imaging of small molecules using desorption/ionization on silicon

ANALYTICAL CHEMISTRY, 79(10), 3535–3541.

By: Q. Liu n, Z. Guo n & L. He n

MeSH headings : Animals; Cell Line; Cytological Techniques; Diagnostic Imaging / methods; Humans; Lasers; Liver / cytology; Liver / ultrastructure; Mass Spectrometry / methods; Mice; Phosphatidylcholines; Propidium; Silicon
TL;DR: The use of a matrix-free mass spectrometric imaging method, i.e., desorption/ionization on silicon (DIOS), for biological surface analysis, and a good correlation of the spatial distribution of cells confirmed the validity of this DIOS imaging approach. (via Semantic Scholar)
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Source: Web Of Science
Added: August 6, 2018

2007 journal article

Quantitative study of solvent and surface effects on analyte ionization in desorption ionization on silicon (DIOS) mass spectrometry

JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY, 19(1), 8–13.

By: Q. Liu n & L. He n

TL;DR: Improved MS detection of small molecules via proper surface treatment and solvent selection is demonstrated and a direct correlation between ionization of triethylamine and the relative acidities of the surface and the solvent is evident. (via Semantic Scholar)
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Source: Web Of Science
Added: August 6, 2018

2005 review

Nanomaterials in mass spectrometry ionization and prospects for biological application

[Review of ]. ANALYTICAL AND BIOANALYTICAL CHEMISTRY, 384(3), 584–592.

By: Z. Guo n, A. Ganawi n, Q. Liu n & L. He n

author keywords: nanomaterials; mass spectrometry; bioanalysis
MeSH headings : Biology; Mass Spectrometry / methods; Nanostructures / analysis; Nanostructures / chemistry; Nanostructures / ultrastructure; Sensitivity and Specificity
TL;DR: A brief review summarizes recent developments in the field with the focus on the use of nanomaterials as alternative media to facilitate analyte ionization in laser-desorption ionization–mass spectrometry (LDI–MS) and secondary ion mass spectrometer (SIMS). (via Semantic Scholar)
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Source: Web Of Science
Added: August 6, 2018

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