Li Na Loo

Works (5)

Updated: July 29th, 2023 21:16

2010 article

The Red clover necrotic mosaic virus Capsid as a Multifunctional Cell Targeting Plant Viral Nanoparticle

Lockney, D. M., Guenther, R. N., Loo, L., Overton, W., Antonelli, R., Clark, J., … Franzen, S. (2010, December 2). Bioconjugate Chemistry, Vol. 22, pp. 67–73.

By: D. Lockney n, R. Guenther n, L. Loo n, W. Overton  n, R. Antonelli n, J. Clark  n, M. Hu n, C. Luft n, S. Lommel n, S. Franzen n 

MeSH headings : Amino Acid Sequence; Biological Availability; Biological Transport; Capsid / chemistry; Capsid / metabolism; Doxorubicin / chemistry; Doxorubicin / pharmacokinetics; Fluorescent Dyes / chemistry; HeLa Cells; Humans; Models, Molecular; Nanoparticles / chemistry; Peptides / chemistry; Peptides / metabolism; Plants / virology; Protein Conformation; Surface Properties; Tombusviridae
topics (OpenAlex): Plant Virus Research Studies; Bacteriophages and microbial interactions; Transgenic Plants and Applications
TL;DR: It is shown that targeting peptides (less than 16 amino acids) can be conjugated to the capsid using the heterobifunctional chemical linker sulfosuccinimidyl-4-(N-maleimidomethyl)cyclohexane-1-carboxylate (Sulfo-SMCC). (via Semantic Scholar)
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Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2007 article

Cellular Uptake of Gold Nanoparticles Passivated with BSA−SV40 Large T Antigen Conjugates

Ryan, J. A., Overton, K. W., Speight, M. E., Oldenburg, C. N., Loo, L. N., Robarge, W., … Feldheim, D. L. (2007, October 31). Analytical Chemistry, Vol. 79, pp. 9150–9159.

By: J. Ryan n, K. Overton n, M. Speight n, C. Oldenburg n, L. Loo n, W. Robarge n, S. Franzen n , D. Feldheim n

MeSH headings : Antigens, Polyomavirus Transforming / metabolism; Cell Nucleus / metabolism; Gold / chemistry; HeLa Cells; Humans; Metal Nanoparticles; Reproducibility of Results; Serum Albumin, Bovine / metabolism; Subcellular Fractions / metabolism
topics (OpenAlex): Gold and Silver Nanoparticles Synthesis and Applications; Advanced biosensing and bioanalysis techniques; RNA Interference and Gene Delivery
TL;DR: The ICP-OES and nuclear fractionation techniques reported here are valuable tools that can add important quantitative information to optical and electron imaging methods such as VEC-DIC and transmission electron microscopy regarding the fate of nanoparticles in cells. (via Semantic Scholar)
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Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2007 article

Encapsidation of Nanoparticles by Red Clover Necrotic Mosaic Virus

Loo, L. N., Guenther, R. H., Lommel, S. A., & Franzen, S. (2007, August 18). Journal of the American Chemical Society, Vol. 129, pp. 11111–11117.

By: L. Loo n, R. Guenther n, S. Lommel n & S. Franzen n 

MeSH headings : Biocompatible Materials; Capsid / physiology; Capsid Proteins / genetics; Capsid Proteins / metabolism; Cobalt / chemistry; Ferric Compounds / chemistry; Gold / chemistry; Nanoparticles / chemistry; Nanotechnology; Quantum Dots; Tombusviridae / physiology; Virus Assembly
topics (OpenAlex): Plant Virus Research Studies; Bacteriophages and microbial interactions; Viral gastroenteritis research and epidemiology
TL;DR: Covalent linkage of the OAS to nanoparticles directs RNA-dependent encapsidation and demonstrates that foreign cargo can be packaged into RCNMV virions. (via Semantic Scholar)
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Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2007 article

Infusion of dye molecules into Red clover necrotic mosaic virus

Loo, L. N., Guenther, R. H., Lommel, S. A., & Franzen, S. (2007, November 23). Chemical Communications, pp. 88–90.

By: L. Loo n, R. Guenther n, S. Lommel n & S. Franzen n 

MeSH headings : Capsid Proteins / chemistry; Capsid Proteins / metabolism; Coloring Agents / analysis; Coloring Agents / metabolism; Doxorubicin / metabolism; Microscopy, Electron, Transmission; Tombusviridae / chemistry; Tombusviridae / metabolism; Tombusviridae / ultrastructure
topics (OpenAlex): Plant Virus Research Studies; Bacteriophages and microbial interactions; Transgenic Plants and Applications
TL;DR: The Red clover necrotic mosaic virus capsid is utilized to package and release molecules through reversible depletion and re-addition of divalent cations. (via Semantic Scholar)
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Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2006 article

Controlled Encapsidation of Gold Nanoparticles by a Viral Protein Shell

Loo, L. N., Guenther, R. H., Basnayake, V. R., Lommel, S. A., & Franzen, S. (2006, March 17). Journal of the American Chemical Society, Vol. 128, pp. 4502–4503.

By: L. Loo n, R. Guenther n, V. Basnayake n, S. Lommel n & S. Franzen n 

MeSH headings : Capsid Proteins / chemistry; Capsid Proteins / genetics; DNA, Viral / chemistry; DNA, Viral / genetics; Gold / chemistry; Metal Nanoparticles / chemistry; Microscopy, Electron, Transmission; RNA, Viral / chemistry; RNA, Viral / genetics; Tombusviridae / chemistry; Tombusviridae / genetics
topics (OpenAlex): Plant Virus Research Studies; Bacteriophages and microbial interactions; Animal Virus Infections Studies
TL;DR: Covalent linkage of the OAS to Au functions as a trigger for specific encapsidation and demonstrates that foreign cargo can be packaged into Red clover necrotic mosaic virus virions. (via Semantic Scholar)
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UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

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