Works (17)

Updated: July 5th, 2023 15:56

2017 journal article

Impact of growth mode, phase, and rate on the metabolic state of the extremely thermophilic archaeon Pyrococcus furiosus

BIOTECHNOLOGY AND BIOENGINEERING, 114(12), 2947–2954.

By: P. Khatibi n, C. Chou n, A. Loder n, J. Zurawski n, M. Adams* & R. Kelly n

author keywords: continuous culture; growth phase; growth rate; hyperthermophiles; Pyrococcus furiosus; transcriptome
MeSH headings : Archaeal Proteins / metabolism; Batch Cell Culture Techniques / methods; Cell Proliferation / physiology; Energy Metabolism / physiology; Pyrococcus furiosus / growth & development; Pyrococcus furiosus / metabolism; Transcriptome / physiology
Sources: Web Of Science, ORCID
Added: August 6, 2018

2014 journal article

Control of Protein Function through Optochemical Translocation

ACS SYNTHETIC BIOLOGY, 3(10), 731–736.

By: H. Engelke*, C. Chou n, R. Uprety n, P. Jess* & A. Deiters n

co-author countries: Germany 🇩🇪
author keywords: protein control; optogenetics; nuclear import; photocontrolled transcription; photocontrolled TEV-cleavage
MeSH headings : Active Transport, Cell Nucleus / radiation effects; Amino Acid Sequence; Endopeptidases / genetics; Endopeptidases / metabolism; Endopeptidases / radiation effects; Forkhead Box Protein O3; Forkhead Transcription Factors / genetics; Forkhead Transcription Factors / metabolism; Forkhead Transcription Factors / radiation effects; HEK293 Cells; Humans; Light; Matrix Attachment Region Binding Proteins / genetics; Matrix Attachment Region Binding Proteins / metabolism; Matrix Attachment Region Binding Proteins / radiation effects; Molecular Sequence Data; Nuclear Localization Signals / genetics; Photochemical Processes; Protein Engineering / methods; Synthetic Biology
Source: Web Of Science
Added: August 6, 2018

2014 journal article

Genetically Encoded Optochemical Probes for Simultaneous Fluorescence Reporting and Light Activation of Protein Function with Two-Photon Excitation

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 136(44), 15551–15558.

By: J. Luo n, R. Uprety n, Y. Naro*, C. Chou n, D. Nguyen*, J. Chin*, A. Deiters*

co-author countries: United Kingdom of Great Britain and Northern Ireland 🇬🇧
MeSH headings : Chromatography, Liquid; Fluorescence; HEK293 Cells; Humans; Methanosarcina barkeri / chemistry; Molecular Probes; Photons; Proteins / chemistry; Proteins / physiology; Tandem Mass Spectrometry
Source: Web Of Science
Added: August 6, 2018

2014 journal article

Synthesis of Non-linear Protein Dimers through a Genetically Encoded Thiol-ene Reaction

PLOS ONE, 9(9).

By: J. Torres-Kolbus n, C. Chou n, J. Liu* & A. Deiters n

MeSH headings : Alkenes / metabolism; Animals; Fluorescent Dyes / metabolism; Green Fluorescent Proteins / metabolism; Lysine / metabolism; Methanosarcina barkeri / metabolism; Muramidase / metabolism; Myoglobin / metabolism; Protein Multimerization; Sulfhydryl Compounds / metabolism
Source: Web Of Science
Added: August 6, 2018

2013 journal article

Genetically encoded light-activated transcription for spatiotemporal control of gene expression and gene silencing in mammalian cells

Journal of the American Chemical Society, 135(36), 13433–13439.

By: J. Hemphill n, C. Chou n, J. Chin* & A. Deiters n

co-author countries: United Kingdom of Great Britain and Northern Ireland 🇬🇧
MeSH headings : Activating Transcription Factors / genetics; Activating Transcription Factors / metabolism; DNA-Directed RNA Polymerases / genetics; DNA-Directed RNA Polymerases / metabolism; Gene Expression Regulation, Enzymologic / genetics; Gene Silencing; Green Fluorescent Proteins / genetics; Green Fluorescent Proteins / metabolism; HEK293 Cells; Humans; Light; Luciferases / genetics; Luciferases / metabolism; Models, Molecular; Molecular Structure; Photochemical Processes; Protein Engineering; Viral Proteins / genetics; Viral Proteins / metabolism
Source: NC State University Libraries
Added: August 6, 2018

2012 journal article

Genetically encoded norbornene directs site-specific cellular protein labelling via a rapid bioorthogonal reaction

NATURE CHEMISTRY, 4(4), 298–304.

By: K. Lang*, L. Davis*, J. Torres-Kolbus n, C. Chou n, A. Deiters n & J. Chin*

co-author countries: United Kingdom of Great Britain and Northern Ireland 🇬🇧
MeSH headings : Amino Acids / metabolism; Amino Acyl-tRNA Synthetases / metabolism; Cell Line; Fluorescent Dyes / chemistry; Green Fluorescent Proteins / genetics; Green Fluorescent Proteins / metabolism; Humans; Lysine / analogs & derivatives; Lysine / metabolism; Norbornanes / chemistry; Proteins / genetics; Proteins / metabolism; Rhodamines / chemistry
Source: Web Of Science
Added: August 6, 2018

2011 journal article

Genetically encoding an aliphatic diazirine for protein photocrosslinking

CHEMICAL SCIENCE, 2(3), 480–483.

By: C. Chou n, R. Uprety n, L. Davis*, J. Chin* & A. Deiters n

co-author countries: United Kingdom of Great Britain and Northern Ireland 🇬🇧
Source: Web Of Science
Added: August 6, 2018

2011 journal article

Light-Activated Gene Editing with a Photocaged Zinc-Finger Nuclease

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 50(30), 6839–6842.

By: C. Chou n & A. Deiters n

author keywords: caged compounds; gene technology; light-activation; mutagenesis; zinc-finger nucleases
MeSH headings : Endonucleases / genetics; Endonucleases / metabolism; Escherichia coli / genetics; HEK293 Cells; Humans; Models, Molecular; Mutagenesis; Photochemical Processes; Protein Engineering; Tyrosine / genetics; Ultraviolet Rays; Zinc Fingers
Source: Web Of Science
Added: August 6, 2018

2010 journal article

Photocaged T7 RNA Polymerase for the Light Activation of Transcription and Gene Function in Pro- and Eukaryotic Cells

CHEMBIOCHEM, 11(7), 972–977.

By: C. Chou n, D. Young n & A. Deiters n

author keywords: amino acids; caged proteins; light activation; polymerases; RNA
MeSH headings : Catalytic Domain; Cell Line; DNA-Directed RNA Polymerases / genetics; DNA-Directed RNA Polymerases / metabolism; Escherichia coli / enzymology; Humans; Luciferases / genetics; Luciferases / metabolism; Models, Molecular; Photochemical Processes; Transcriptional Activation; Tyrosine / chemistry; Ultraviolet Rays; Viral Proteins / genetics; Viral Proteins / metabolism
Source: Web Of Science
Added: August 6, 2018

2009 journal article

A Light-Activated DNA Polymerase

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 48(32), 5950–5953.

By: C. Chou n, D. Young n & A. Deiters n

author keywords: DNA polymerases; mutagenesis; non-natural amino acids; photoactivation; polymerase chain reaction
MeSH headings : Catalytic Domain; Mutation; Nitrobenzenes / chemistry; Photolysis; Polymerase Chain Reaction; Taq Polymerase / chemistry; Taq Polymerase / metabolism; Tyrosine / chemistry; Ultraviolet Rays
Source: Web Of Science
Added: August 6, 2018

2009 journal article

Plant cell calcium-rich environment enhances thermostability of recombinantly produced α-amylase from the hyperthermophilic bacterium Thermotoga maritime

Biotechnology and Bioengineering, 104(5), 947–956.

By: M. Santa-Maria n, C. Chou n, G. Yencho n, C. Haigler n, W. Thompson n, R. Kelly n, B. Sosinski n

author keywords: hyperthermophilic enzymes; starch processing; transgenic plants; tobacco NT1 Cell cultures; biofuel
MeSH headings : Calcium / pharmacology; Coenzymes / pharmacology; Enzyme Stability; Escherichia coli / enzymology; Escherichia coli / genetics; Hot Temperature; Plants, Genetically Modified / enzymology; Recombinant Proteins / chemistry; Recombinant Proteins / genetics; Recombinant Proteins / metabolism; Thermotoga maritima / enzymology; Thermotoga maritima / genetics; Tobacco / enzymology; Tobacco / genetics; alpha-Amylases / chemistry; alpha-Amylases / genetics; alpha-Amylases / metabolism
Sources: Web Of Science, ORCID, Crossref
Added: August 6, 2018

2009 journal article

Temperature, not LuxS, mediates AI-2 formation in hydrothermal habitats

FEMS MICROBIOLOGY ECOLOGY, 68(2), 173–181.

By: J. Nichols n, M. Johnson n, C. Chou n & R. Kelly n

author keywords: autoinducer-2; AI-2; hyperthermophiles; hydrothermal environments; Thermotoga maritima; Pyrococcus furiosus
MeSH headings : Bacterial Proteins / genetics; Bacterial Proteins / metabolism; Carbon-Sulfur Lyases / genetics; Carbon-Sulfur Lyases / metabolism; Gas Chromatography-Mass Spectrometry; Gene Expression Regulation, Bacterial; Homoserine / analogs & derivatives; Homoserine / biosynthesis; Hot Temperature; Lactones; Pyrococcus furiosus / genetics; Pyrococcus furiosus / metabolism; Quorum Sensing; Thermotoga maritima / genetics; Thermotoga maritima / metabolism
Sources: Web Of Science, ORCID
Added: August 6, 2018

2008 journal article

Functional-genomics-based identification and characterization of open reading frames encoding alpha-glucoside-processing enzymes in the hyperthermophilic archaeon Pyrococcus furiosus

APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 74(4), 1281–1283.

By: D. Comfort n, C. Chou n, S. Conners n, A. VanFossen n & R. Kelly n

MeSH headings : Computational Biology; Gene Expression Regulation, Bacterial / genetics; Genomics / methods; Open Reading Frames / genetics; Pyrococcus furiosus / enzymology; Pyrococcus furiosus / genetics; alpha-Glucosidases / genetics; beta-Amylase / genetics
Sources: Web Of Science, ORCID
Added: August 6, 2018

2008 review

Hydrogenesis in hyperthermophilic microorganisms: Implications for biofuels

[Review of ]. METABOLIC ENGINEERING, 10(6), 394–404.

By: C. Chou n, F. Jenney*, M. Adams* & R. Kelly n

author keywords: Biohydrogen; Pyrococcus furiosus; Thermotoga maritima; Caldicellulosiruptor saccharolyticus; Hyperthermophiles; Hydrogenases
MeSH headings : Archaea / metabolism; Bioelectric Energy Sources; Hot Temperature; Hydrogen / metabolism; Hydrogen Sulfide / metabolism; Methane / metabolism
Sources: Web Of Science, ORCID
Added: August 6, 2018

2007 journal article

Impact of substrate glycoside linkage. and elemental sulfur on bioenergetics, of and hydrogen production by the hyperthermophilic Archaeon Pyrococcus furiosus

APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 73(21), 6842–6853.

By: C. Chou n, K. Shockley n, S. Conners n, D. Lewis n, D. Comfort n, M. Adams*, R. Kelly n

MeSH headings : Archaea; Chemical Phenomena; Chemistry; Gene Expression Regulation, Archaeal; Genome, Archaeal; Glycosides / metabolism; Hot Temperature; Hydrogen / metabolism; Oligonucleotide Array Sequence Analysis; Open Reading Frames; Pyrococcus furiosus / enzymology; Pyrococcus furiosus / genetics; Pyrococcus furiosus / physiology; Sulfur / metabolism
Sources: Web Of Science, ORCID
Added: August 6, 2018

2007 journal article

Responses of wild-type and resistant strains of the hyperthermophilic bacterium Thermotoga maritima to chloramphenicol challenge

APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 73(15), 5058–5065.

By: C. Montero n, M. Johnson n, C. Chou n, S. Conners n, S. Geouge n, S. Tachdjian n, J. Nichols n, R. Kelly n

MeSH headings : Anti-Bacterial Agents / pharmacology; Bacterial Proteins / genetics; Bacterial Proteins / metabolism; Base Sequence; Chloramphenicol / pharmacology; Drug Resistance, Bacterial / genetics; Gene Expression Profiling; Gene Expression Regulation, Bacterial; Hot Temperature; Microbial Sensitivity Tests; Molecular Sequence Data; Oligonucleotide Array Sequence Analysis; Point Mutation; Proteome; RNA, Ribosomal, 23S / genetics; Thermotoga maritima / drug effects; Thermotoga maritima / genetics; Thermotoga maritima / growth & development; Transcription, Genetic
Sources: Web Of Science, ORCID
Added: August 6, 2018

2006 journal article

Transcriptional and biochemical analysis of starch metabolism in the hyperthermophilic archaeon Pyrococcus furiosus

JOURNAL OF BACTERIOLOGY, 188(6), 2115–2125.

By: H. Lee*, K. Shockley n, G. Schut*, S. Conners n, C. Montero n, M. Johnson n, C. Chou n, S. Bridger n ...

MeSH headings : Archaeal Proteins / genetics; Bacterial Proteins / genetics; DNA, Archaeal / chemistry; DNA, Archaeal / genetics; Gene Expression Profiling; Gene Expression Regulation, Archaeal; Glucose / metabolism; Glucosephosphates / metabolism; Glucosyltransferases / genetics; Glycogen Debranching Enzyme System / genetics; Glycoside Hydrolases / genetics; Monosaccharide Transport Proteins / genetics; Oligonucleotide Array Sequence Analysis; Pyrococcus furiosus / genetics; Pyrococcus furiosus / metabolism; Sequence Analysis, DNA; Starch / metabolism; Substrate Specificity
Sources: Web Of Science, ORCID
Added: August 6, 2018

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