Works (16)
Updated: July 5th, 2023 15:55
2020 journal article
Multicenter flow cytometry proficiency testing of canine blood and lymph node samples
Veterinary Clinical Pathology, 49(2), 249–257.
author keywords: assay performance; dog; external laboratory quality assessment; immunophenotyping
MeSH headings : Animals; Cross-Sectional Studies; Dog Diseases / blood; Dog Diseases / diagnosis; Dog Diseases / pathology; Dogs; Flow Cytometry / standards; Flow Cytometry / veterinary; Hematologic Neoplasms / diagnosis; Hematologic Neoplasms / pathology; Hematologic Neoplasms / veterinary; Immunophenotyping / veterinary; Laboratory Proficiency Testing / standards; Lymph Nodes / pathology; Lymphoproliferative Disorders / diagnosis; Lymphoproliferative Disorders / pathology; Lymphoproliferative Disorders / veterinary
TL;DR:
Lymphoproliferations were readily identified by FC, but identification of the categories of hematolymphoid neoplasia in fresh samples or archived files was variable, indicating a need for a more standardized approach to maximize the enormous potential of FC in veterinary medicine.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries, Crossref, ORCID
Added: April 20, 2020
2018 journal article
Genetic conservation of Cytauxzoon felis antigens and mRNA expression in the schizont life-stage
VETERINARY PARASITOLOGY, 263, 49–53.
author keywords: Feline; Cytauxzoon felis; Cytauxzoonosis; Antigen; Vaccine candidate; Genetic conservation
MeSH headings : Animals; Antigens, Protozoan / genetics; Cat Diseases / parasitology; Cats; DNA, Protozoan / genetics; Piroplasmida / genetics; Protozoan Infections, Animal / mortality; Protozoan Infections, Animal / parasitology; Protozoan Infections, Animal / prevention & control; Protozoan Vaccines / genetics; Protozoan Vaccines / immunology; RNA, Messenger / genetics; Schizonts / genetics
TL;DR:
The suitability of three C. felis antigens for further investigation as vaccine candidates against cytauxzoonosis is assessed and robust levels of all transcripts in the schizont life stage of the parasite are revealed.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: December 3, 2018
2018 journal article
Identification of Cytauxzoon felis antigens via protein microarray and assessment of expression library immunization against cytauxzoonosis
CLINICAL PROTEOMICS, 15(1).
Contributors: M. Schreeg n, H. Marr n, n, M. Sherrill*, H. Outi*, E. Scholl n, D. Bird n , A. Vigil*
author keywords: Cytauxzoonosis; Cytauxzoon felis; Expression library immunization; Protein microarray; Piroplasmid; Vaccine
TL;DR:
Protein microarray facilitated high-throughput identification of novel antigens, substantially increasing the pool of characterized C. felis Antigens and should be considered for development of C.Felis vaccines, diagnostics, and therapeutics.
(via Semantic Scholar)
open access via doi.org (publisher)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: January 14, 2019
2016 journal article
Mitochondrial Genome Sequences and Structures Aid in the Resolution of Piroplasmida phylogeny
PLOS ONE, 11(11).
Contributors: M. Schreeg n, H. Marr n, n, L. Cohn *, D. Bird n , E. Scholl n, M. Levy n, B. Wiegmann n , A. Birkenheuer n
MeSH headings : DNA, Protozoan / genetics; Genome, Mitochondrial; Humans; Phylogeny; Piroplasmida / classification; Piroplasmida / genetics; Protozoan Infections / parasitology
TL;DR:
Phylogenetic analysis of concatenated mitochondrial and 18S sequences as well as cox1 amino acid sequence identified five distinct Piroplasmida groups, each of which possesses a unique mitochondrial genome structure.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries, ORCID
Added: August 6, 2018
2016 journal article
PCR amplification of a multi-copy mitochondrial gene (cox3) improves detection of Cytauxzoon felis infection as compared to a ribosomal gene (18S)
VETERINARY PARASITOLOGY, 225, 123–130.
Contributors: M. Schreeg n, H. Marr n, E. Griffith n , n, D. Bird n , M. Reichard *, L. Cohn *, M. Levy n, A. Birkenheuer n
author keywords: Cytauxzoonosis; Cytochrome c oxidase; Piroplasmosis; Mitochondria; Feline; Molecular diagnostic assays
MeSH headings : Animals; Cat Diseases / diagnosis; Cats; DNA, Protozoan / blood; DNA, Protozoan / genetics; Electron Transport Complex IV / genetics; Gene Dosage; Haemosporida / genetics; Polymerase Chain Reaction / standards; Polymerase Chain Reaction / veterinary; Protozoan Infections, Animal / diagnosis; RNA, Ribosomal, 18S / genetics; Sensitivity and Specificity
TL;DR:
A PCR assay targeting the C. felis mitochondrial gene cytochrome c oxidase subunit III (cox3) is designed and demonstrated that the cox3 PCR can detect as low as 1 copy of DNA target and can detect C.Felis during early infections.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018
2015 journal article
Rapid High-Resolution Melt Analysis of Cytauxzoon felis Cytochrome b To Aid in the Prognosis of Cytauxzoonosis
JOURNAL OF CLINICAL MICROBIOLOGY, 53(8), 2517–2524.
MeSH headings : Alleles; Animals; Antiprotozoal Agents / therapeutic use; Atovaquone / therapeutic use; Azithromycin / therapeutic use; Cat Diseases / diagnosis; Cat Diseases / drug therapy; Cat Diseases / parasitology; Cats; Cytochromes b / genetics; Genotype; Genotyping Techniques / methods; Piroplasmida / drug effects; Piroplasmida / genetics; Piroplasmida / isolation & purification; Polymerase Chain Reaction / methods; Prognosis; Protozoan Infections, Animal / diagnosis; Protozoan Infections, Animal / drug therapy; Protozoan Infections, Animal / parasitology; Protozoan Proteins / genetics; Sensitivity and Specificity; Transition Temperature; Veterinary Medicine / methods
TL;DR:
The purpose of this study was to design a PCR panel that could distinguish C. felis cytb1 from other cytochrome b genotypes, and this panel was predicted to distinguish cytb 1 from other cytb genotypes through the use of high-resolution melt analysis.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018
2013 journal article
A Novel Candidate Vaccine for Cytauxzoonosis Inferred from Comparative Apicomplexan Genomics
PLOS ONE, 8(8).
Contributors: n, E. Scholl n, D. Bird n, C. Brown *, L. Cohn *, G. Dean n, M. Levy n, D. Doolan *
MeSH headings : Animals; Antigens, Protozoan / genetics; Antigens, Protozoan / immunology; Cat Diseases / immunology; Cat Diseases / parasitology; Cat Diseases / prevention & control; Cats; Cattle; Conserved Sequence; Genome, Protozoan; Genomics; Immune Sera / immunology; Piroplasmida / genetics; Piroplasmida / immunology; Protozoan Infections, Animal / immunology; Protozoan Infections, Animal / parasitology; Protozoan Infections, Animal / prevention & control; Protozoan Proteins / genetics; Protozoan Proteins / immunology; Protozoan Vaccines / genetics; Protozoan Vaccines / immunology; Recombinant Proteins / genetics; Recombinant Proteins / immunology; Synteny; Theileria parva / genetics; Theileria parva / immunology
TL;DR:
Comparative genomics is used to computationally and experimentally interpret the C. felis genome to identify a novel candidate vaccine antigen for cytauxzoonosis, and this approach emphasizes the use of comparative genomics as an accelerated path to developing vaccines against experimentally intractable pathogens.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018
2013 journal article
Pharmacogenomics of Cytauxzoon felis Cytochrome b: Implications for Atovaquone and Azithromycin Therapy in Domestic Cats with Cytauxzoonosis
JOURNAL OF CLINICAL MICROBIOLOGY, 51(9), 3066–3069.
MeSH headings : Animals; Anti-Infective Agents / pharmacokinetics; Anti-Infective Agents / therapeutic use; Atovaquone / pharmacokinetics; Atovaquone / therapeutic use; Azithromycin / pharmacokinetics; Azithromycin / therapeutic use; Cat Diseases / drug therapy; Cat Diseases / parasitology; Cats; Cytochromes b / genetics; Cytochromes b / metabolism; Pharmacogenetics; Piroplasmida / genetics; Piroplasmida / metabolism; Protozoan Infections / drug therapy; Protozoan Infections / parasitology
TL;DR:
This work characterized the C. felis cytochrome b gene (cytb) in cats with cytauxzoonosis and found a cytb genotype that was associated with survival in A&A-treated cats.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018
2010 journal article
Francisella philomiragia Septicemia in a Dog
JOURNAL OF VETERINARY INTERNAL MEDICINE, 24(4), 969–972.
MeSH headings : Animals; Anti-Bacterial Agents / therapeutic use; Anti-Inflammatory Agents / therapeutic use; Dog Diseases / blood; Dog Diseases / drug therapy; Dog Diseases / microbiology; Dogs; Francisella / classification; Gram-Negative Bacterial Infections / drug therapy; Gram-Negative Bacterial Infections / microbiology; Gram-Negative Bacterial Infections / veterinary; Male; Prednisone / therapeutic use; Sepsis / blood; Sepsis / drug therapy; Sepsis / microbiology; Sepsis / veterinary
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries, ORCID
Added: August 6, 2018
2009 article
What is your diagnosis? Nasal discharge from a dog
Piperisova, I., Neel, J. A., & Tarigo, J. (2010, March). VETERINARY CLINICAL PATHOLOGY, Vol. 39, pp. 121–122.
Contributors: I. Piperisova*, J. Neel* & n
author keywords: Capillariasis; cytology; eggs; Eucoleus boehmi; nasal discharge
MeSH headings : Animals; Anthelmintics / therapeutic use; Capillaria / isolation & purification; Dog Diseases / diagnosis; Dog Diseases / drug therapy; Dog Diseases / pathology; Dogs; Enoplida Infections / diagnosis; Enoplida Infections / drug therapy; Enoplida Infections / pathology; Enoplida Infections / veterinary; Fenbendazole / therapeutic use; Male; Nose Diseases / drug therapy; Nose Diseases / parasitology; Nose Diseases / pathology; Nose Diseases / veterinary
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries, ORCID
Added: August 6, 2018
2008 journal article
Erythrophagocytic low-grade extranodal T-cell lymphoma in a cat
Veterinary Clinical Pathology, 37(4), 416–421.
author keywords: Cat; erythrophagia; hepatosplenic; lymphoma; PARR
MeSH headings : Animals; Bone Marrow / metabolism; Cat Diseases / pathology; Cats; Liver / pathology; Lymphoma, T-Cell / pathology; Lymphoma, T-Cell / veterinary; Male; Spleen / pathology; Splenic Neoplasms / pathology; Splenic Neoplasms / veterinary
TL;DR:
This report documents the first case of an erythrophagocytic T-cell lymphoma in a cat, a neoplasm described previously only in humans and dogs.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, Crossref
Added: August 6, 2018
2008 journal article
What is your diagnosis? Particulate material in peritoneal fluid from a dog
VETERINARY CLINICAL PATHOLOGY, 37(1), 129–131.
Contributors: J. Renschler n, n, J. Neel n & C. Grindem n
author keywords: abdominal fluid; barium sulfate; dog; lymphoma; peritonitis; radiographic contrast
MeSH headings : Animals; Ascitic Fluid / chemistry; Barium Sulfate / analysis; Dog Diseases / diagnosis; Dogs; Lymphoma / diagnosis; Lymphoma / veterinary; Male
TL;DR:
9-year-old castrated male Greyhound dog was presented for evaluation of vomiting and lethargy of 1-week duration and received chemotherapy for treatment of lymphoma.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries, ORCID
Added: August 6, 2018
2007 article
Cerebrospinal fluid from a dog with hind limb ataxia
Snyder, L. A., Tarigo, J. L., & Neel, J. A. (2007, December). VETERINARY CLINICAL PATHOLOGY, Vol. 36, pp. 379–381.
author keywords: additive; artifact; blood collection tube; cerebrospinal fluid; dog; silica
MeSH headings : Animals; Artifacts; Ataxia / diagnosis; Ataxia / pathology; Ataxia / veterinary; Cerebrospinal Fluid; Dog Diseases / diagnosis; Dog Diseases / pathology; Dogs; Female; Hindlimb / pathology; Specimen Handling / veterinary
TL;DR:
The microscopic appearance of highly concentrated silica particles in cytocentrifuged preparations of CSF is documented and the importance of recognizing and identifying this artifact in cytologic preparations is underscored.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries, ORCID
Added: August 6, 2018
2007 journal article
Deep and superficial skin scrapings from a feline immunodeficiency virus-positive cat
VETERINARY CLINICAL PATHOLOGY, 36(1), 101–104.
Contributors: J. Neel n , n, K. Tater n & C. Grindem n
author keywords: cat; demodicosis; feline immunodeficiency virus
MeSH headings : Animals; Cat Diseases / diagnosis; Cat Diseases / parasitology; Cat Diseases / pathology; Cats; Immunodeficiency Virus, Feline / isolation & purification; Lentivirus Infections / veterinary; Male; Mite Infestations / diagnosis; Mite Infestations / pathology; Mite Infestations / veterinary; Mites / anatomy & histology
TL;DR:
An 8-year-old, neutered male, domestic shorthair cat housed at the North Carolina State University, College of Veterinary Medicine, Laboratory Animal Research facility as part of a research colony was examined because of mulifocal skin lesions, finding demodicosis, with Demodex cati and D gatoi co-infection.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries, ORCID
Added: August 6, 2018
2006 journal article
Gallbladder aspirate from a dog
VETERINARY CLINICAL PATHOLOGY, 35(4), 467–470.
Contributors: J. Neel n , n & C. Grindem n
MeSH headings : Animals; Cholecystitis / microbiology; Cholecystitis / pathology; Cholecystitis / veterinary; Dog Diseases / diagnosis; Dogs; Gallbladder; Male; Mycoses / microbiology; Mycoses / pathology; Mycoses / veterinary; Saccharomycopsis / isolation & purification
TL;DR:
This case highlights the role of bactibilia in the development of acute cholecystitis and the unique cytologic appearance of C guttulatus as an incidental finding in bile fluid.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries, ORCID
Added: August 6, 2018
2006 journal article
What is your diagnosis? Reluctant to dive: coelomic effusion in a frog
VETERINARY CLINICAL PATHOLOGY, 35(3), 341–344.
Contributors: n, K. Linder n, J. Neel n , S. Harvey n, A. Remick n & C. Grindem n
author keywords: amphibian; cytology; mycobacteriosis; Xenopus
MeSH headings : Animals; Fatal Outcome; Female; Mycobacterium Infections, Nontuberculous / diagnosis; Mycobacterium Infections, Nontuberculous / pathology; Mycobacterium Infections, Nontuberculous / veterinary; Mycobacterium marinum / isolation & purification; Polymerase Chain Reaction / veterinary; Staining and Labeling / methods; Staining and Labeling / veterinary; Xenopus laevis / microbiology
TL;DR:
Cytologic examination of coelomic effusion fluid at the NCSU veterinary teaching hospital revealed a mixed population of inflammatory cells, including heterophils and a predominance of large mononuclear cells (macrophages) that often contained intracytoplasmic, negatively-stained, rod-shaped to filamentous organisms consistent with Mycobacterium sp.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries, ORCID
Added: August 6, 2018
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