Nathan J. Cherrington

Works (4)

Updated: July 5th, 2023 16:04

1998 journal article

Flavin-containing monooxygenase and cytochrome P450 mediated metabolism of pesticides: from mouse to human

Reviews in Toxicology, 2(1998), 231–243.

By: E. Hodgson, N. Cherrington, S. Coleman, S. Liu, J. Falls, Y. Cao, J. Goldstein, R. Rose

Source: NC State University Libraries
Added: August 6, 2018

1998 journal article

Molecular cloning, sequence, and expression of mouse flavin-containing monooxygenases 1 and 5 (FMO1 and FMO5)

Journal of Biochemical and Molecular Toxicology, 12(1998), 205–212.

By: N. Cherrington n, J. Falls n, R. Rose n, K. Clements n, R. Philpot*, P. Levi n, E. Hodgson n

Source: NC State University Libraries
Added: August 6, 2018

1998 journal article

Physiological factors affecting protein expression of flavin-containing monooxygenases 1, 3 and 5

XENOBIOTICA, 28(7), 673–682.

By: N. Cherrington n, Y. Cao n, J. Cherrington n, R. Rose n & E. Hodgson n

MeSH headings : Adult; Animals; Female; Humans; Liver / embryology; Liver / metabolism; Male; Mice; Microsomes, Liver / metabolism; Middle Aged; Oxygenases / biosynthesis; Rats; Sex Characteristics; Species Specificity
TL;DR: The mouse and rat exhibit substantial differences in the gender expression of flavin-containing monooxygenase (FMO) forms, and Methimazole, imipramine and thiobenzamide are much better substrates for FMO1 than for F MO3 or FMO5. (via Semantic Scholar)
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Source: Web Of Science
Added: August 6, 2018

1997 journal article

Molecular cloning, sequencing, and expression in Escherichia coli of mouse flavin-containing monooxygenase 3 (FMO3): Comparison with the human isoform

ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 347(1), 9–18.

By: J. Falls n, N. Cherrington n, K. Clements n, R. Philpot*, P. Levi n, R. Rose n, E. Hodgson n

author keywords: flavin-containing monooxygenase 3; FMO3; FMO3 sequence; FMO3 expression
MeSH headings : Amino Acid Sequence; Animals; Base Sequence; Catalysis; Cloning, Molecular; Electrophoresis, Polyacrylamide Gel; Enzyme Inhibitors / pharmacology; Enzyme Stability; Escherichia coli / genetics; Female; Gene Expression; Humans; Hydrogen-Ion Concentration; Liver / enzymology; Male; Methimazole / metabolism; Mice; Molecular Sequence Data; Oxygenases / chemistry; Oxygenases / genetics; Oxygenases / metabolism; RNA, Messenger / analysis; Recombinant Proteins / chemistry; Recombinant Proteins / metabolism; Sequence Analysis, DNA; Sequence Homology, Amino Acid
TL;DR: The sequence of mouse flavin-containing monooxygenase 3 (FMO3) was obtained from several clones isolated from a mouse liver cDNA library and results of immunoblotting confirmed the tissue- and gender-dependent expression of mouse FMO3. (via Semantic Scholar)
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Source: Web Of Science
Added: August 6, 2018

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