Works (5)
Updated: July 5th, 2023 15:55
2009 journal article
Imidazole metalloporphyrins as photosensitizers for photodynamic therapy: Role of molecular charge, central metal and hydroxyl radical production
CANCER LETTERS, 282(1), 63–76.
author keywords: Structure function relationship; Photophysics; Phototoxicity; Metalloporphyrins; Apoptosis; Fluorescence microscopy; Reactive oxygen species; Hydroxyl radicals
MeSH headings : Adenocarcinoma / drug therapy; Adenocarcinoma / metabolism; Animals; Apoptosis / drug effects; Cell Line, Tumor; Colonic Neoplasms / drug therapy; Colonic Neoplasms / metabolism; HeLa Cells / drug effects; HeLa Cells / metabolism; Humans; Hydroxyl Radical / metabolism; Imidazoles / therapeutic use; Lysosomes / metabolism; Metalloporphyrins / chemical synthesis; Metalloporphyrins / chemistry; Metalloporphyrins / metabolism; Metalloporphyrins / therapeutic use; Mice; Microscopy, Fluorescence; Mitochondria / metabolism; Models, Molecular; Photochemotherapy / methods
TL;DR:
The cationic Pd porphyrin has high potential as a photosensitizer and gives insights into characteristics for improved molecular designs.
(via Semantic Scholar)
open access via europepmc.org (repository)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2008 journal article
Rational or statistical routes from 1-acyldipyrromethanes to meso-substituted porphyrins. Distinct patterns, multiple pyridyl substituents, and amphipathic architectures
JOURNAL OF ORGANIC CHEMISTRY, 73(16), 6187–6201.
MeSH headings : Magnesium / chemistry; Methane / analogs & derivatives; Methane / chemical synthesis; Methane / chemistry; Microwaves; Porphyrins / chemical synthesis; Pyrroles / chemical synthesis; Pyrroles / chemistry
TL;DR:
The rational and statistical routes enable facile conversion of readily available 1-acyldipyrromethanes to diverse porphyrins bearing 1-4 meso substituents for which access is limited via other methods.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2007 journal article
Direct synthesis of magnesium porphine via 1-formyldipyrromethane
JOURNAL OF ORGANIC CHEMISTRY, 72(13), 5008–5011.
MeSH headings : Magnesium / chemistry; Metalloporphyrins / chemical synthesis; Metalloporphyrins / chemistry; Methane / analogs & derivatives; Methane / chemistry; Molecular Structure; Palladium / chemistry; Porphyrins / chemical synthesis; Porphyrins / chemistry; Pyrroles / chemistry; Zinc / chemistry
TL;DR:
The reaction of 1-formyldipyrromethane in toluene at 115 degrees C containing DBU and MgBr2 in the presence of air affords the magnesium chelate Mg(II) porphine in 30-40% yield.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2007 journal article
New route to ABCD-porphyrins via bilanes
JOURNAL OF ORGANIC CHEMISTRY, 72(20), 7701–7714.
MeSH headings : Magnesium / chemistry; Metalloporphyrins / chemical synthesis; Tetrapyrroles / chemistry
TL;DR:
The new route to ABCD-porphyrins retains the desirable features of the existing "2 + 2" (dipyrromethane + dipyrromETHane-1,9-dicarbinol) method, such as absence of scrambling, yet has significant advantages.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2006 journal article
Synthesis of hydrodipyrrins tailored for reactivity at the 1- and 9-positions
TETRAHEDRON, 63(1), 37–55.
author keywords: hydrodipyrrin; 1-pyrroline; pyrrole; hydroporphyrin
TL;DR:
Straightforward access to various hydrodipyrrins should facilitate development of syntheses of diverse hydroporphyrins.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
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