Steven Ryan Bischoff

Works (7)

Updated: July 5th, 2023 15:53

2013 journal article

Differences in X-Chromosome Transcriptional Activity and Cholesterol Metabolism between Placentae from Swine Breeds from Asian and Western Origins

PLOS ONE, 8(1).

By: S. Bischoff n, S. Tsai n, N. Hardison n, A. Motsinger-Reif  n, B. Freking *, D. Nonneman *, G. Rohrer *, J. Piedrahita n 

MeSH headings : Animals; Cholesterol / metabolism; Computational Biology; Female; Fertility / physiology; Gene Expression Profiling / veterinary; Gestational Age; Linear Models; Microarray Analysis / veterinary; Placenta / metabolism; Placenta / physiology; Pregnancy; RNA, Long Noncoding / genetics; Real-Time Polymerase Chain Reaction / veterinary; Reverse Transcriptase Polymerase Chain Reaction / veterinary; Species Specificity; Swine / genetics; Swine / physiology; Transcription, Genetic / physiology; X Chromosome / genetics; X Chromosome / metabolism
TL;DR: This work identifies key metabolic pathways that differ in the placentae of two swine breeds noted for differences in reproductive prolificacy. (via Semantic Scholar)
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Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2012 journal article

Growth Requirements and Chromosomal Instability of Induced Pluripotent Stem Cells Generated from Adult Canine Fibroblasts

Stem Cells and Development, 22(6), 951–963.

By: S. Koh n, R. Thomas n, S. Tsai n, S. Bischoff n, J. Lim n, M. Breen n , N. Olby n , J. Piedrahita n 

Contributors: S. Koh n, R. Thomas n, S. Tsai n, S. Bischoff n, J. Lim n, M. Breen n , N. Olby n , J. Piedrahita n 

MeSH headings : Alkaline Phosphatase / metabolism; Animals; Antigens, Differentiation / genetics; Antigens, Differentiation / metabolism; Cell Differentiation; Cell Shape; Cells, Cultured; Chromosomal Instability; Coculture Techniques; Comparative Genomic Hybridization; Dogs; Fibroblasts / physiology; Gene Expression; In Situ Hybridization, Fluorescence; Induced Pluripotent Stem Cells / enzymology; Induced Pluripotent Stem Cells / pathology; Induced Pluripotent Stem Cells / transplantation; Kruppel-Like Factor 4; Mice; Mice, SCID; Recombinant Proteins / biosynthesis; Recombinant Proteins / genetics; Teratoma / genetics; Teratoma / pathology; Transcription Factors / biosynthesis; Transcription Factors / genetics
TL;DR: The isolated ciPSCs have similar characteristics to ESCs from other species, but the exact cellular mechanisms behind their unique co-dependency on both FGF2 and LIF are still unknown. (via Semantic Scholar)
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Sources: Web Of Science, Crossref, NC State University Libraries, ORCID
Added: August 6, 2018

2010 journal article

Transcriptional profiling of human placentas from pregnancies complicated by preeclampsia reveals disregulation of sialic acid acetylesterase and immune signalling pathways

PLACENTA, 32(2), 175–182.

By: S. Tsai n, N. Hardison n, A. James *, A. Motsinger-Reif n, S. Bischoff n, B. Thames*, J. Piedrahita n 

author keywords: Placenta; Preeclampsia; Maternal hypertension; Sialic acid acetylesterase
MeSH headings : Acetylesterase / biosynthesis; Antigens, CD / biosynthesis; Endoglin; Female; Genome-Wide Association Study; Humans; Infant, Newborn; Inhibins / biosynthesis; Male; Pre-Eclampsia / etiology; Pre-Eclampsia / metabolism; Pregnancy; Protein Array Analysis; Receptors, Cell Surface / biosynthesis; Trophoblasts / physiology; Up-Regulation; Vascular Endothelial Growth Factor Receptor-1 / biosynthesis
TL;DR: Evidence is found of preeclampsia-associated placental upregulation of sialic acid acetylesterase (SIAE), a gene functionally associated with autoimmune diseases, and changes in immune-associated signaling pathways, offering a potential upstream explanation for the shallow trophoblast invasion and inadequate uterine remodeling typically observed in pathogenesis of preeClampsia. (via Semantic Scholar)
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2. Zero Hunger (OpenAlex)
5. Gender Equality (Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2009 journal article

Characterization of Conserved and Nonconserved Imprinted Genes in Swine

BIOLOGY OF REPRODUCTION, 81(5), 906–920.

By: S. Bischoff n, S. Tsai n, N. Hardison n, A. Motsinger-Reif n, B. Freking *, D. Nonneman *, G. Rohrer *, J. Piedrahita n 

author keywords: assisted reproductive technology; comparative genomic imprinting; epigenetics; gene regulation; genomic imprinting; parthenogenesis; placenta; swine parthenote
MeSH headings : Animals; Female; Fetus / anatomy & histology; Gene Expression Profiling; Gene Expression Regulation, Developmental; Genomic Imprinting / genetics; Oligonucleotide Array Sequence Analysis; Organ Size; Parthenogenesis / genetics; Placenta / anatomy & histology; Polymorphism, Single Nucleotide; Pregnancy; Reverse Transcriptase Polymerase Chain Reaction; Staining and Labeling; Swine / genetics
TL;DR: To increase the understanding of imprinted genes in swine, a comprehensive analysis of this gene family was carried out using two complementary approaches: expression and phenotypic profiling of parthenogenetic fetuses, and analysis of imprinting by pyrosequencing. (via Semantic Scholar)
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Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2008 journal article

Identification of SNPs and INDELS in swine transcribed sequences using short oligonucleotide microarrays

BMC Genomics, 9(1), 252.

By: S. Bischoff n, S. Tsai n, N. Hardison n, A. York n, B. Freking *, D. Nonneman *, G. Rohrer *, J. Piedrahita n 

MeSH headings : Animals; Base Sequence; Computational Biology; DNA / genetics; Female; Fetus / metabolism; Gene Expression Profiling; INDEL Mutation; Linear Models; Male; Oligonucleotide Array Sequence Analysis / methods; Oligonucleotide Array Sequence Analysis / statistics & numerical data; Placenta / metabolism; Polymorphism, Single Nucleotide; Pregnancy; RNA / genetics; Species Specificity; Swine / genetics
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2. Zero Hunger (Web of Science)
13. Climate Action (Web of Science)
15. Life on Land (Web of Science)
Sources: Web Of Science, Crossref, NC State University Libraries
Added: August 6, 2018

2008 article

Successful cloning of the Yucatan minipig using commercial/occidental breeds as oocyte donors and embryo recipients

Estrada, J. L., Collins, B., York, A., Bischoff, S., Sommer, J., Tsai, S., … Piedrahita, J. A. (2008, June). CLONING AND STEM CELLS, Vol. 10, pp. 287–296.

By: J. Estrada n, B. Collins n, A. York n, S. Bischoff n, J. Sommer n, S. Tsai n, R. Petters n, J. Piedrahita n 

MeSH headings : Animals; Cell Line; Cloning, Organism / methods; Fibroblasts / cytology; Microsatellite Repeats; Nuclear Transfer Techniques; Oocytes / physiology; Sus scrofa; Swine; Swine, Miniature / embryology
TL;DR: This report shows that it is possible to produce viable Yucatan SCNT clones and opens up the possibility of developing valuable biomedical models in this porcine breed. (via Semantic Scholar)
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Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2006 journal article

Detection of transcriptional difference of porcine imprinted genes using different microarray platforms

BMC Genomics, 7.

By: S. Tsai, B. Mir, A. Martin, J. Estrada, S. Bischoff, W. Hsieh, J. Cassady, B. Freking ...

Source: NC State University Libraries
Added: August 6, 2018

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