Works (4)
Updated: July 5th, 2023 15:54
2008 journal article
Oral Delivery of L-arginine Stimulates Prostaglandin-dependent Secretory Diarrhea in Cryptosporidium parvum–infected Neonatal Piglets
Journal of Pediatric Gastroenterology and Nutrition, 46(2), 139–146.
author keywords: barrier function; enteral nutrition; epithelial defense; nitric oxide
MeSH headings : Alanine / administration & dosage; Analysis of Variance; Animals; Animals, Newborn; Arginine / administration & dosage; Atrophy; Chlorides / metabolism; Cryptosporidiosis / parasitology; Cryptosporidiosis / physiopathology; Cryptosporidiosis / therapy; Cryptosporidium parvum / growth & development; Cyclooxygenase Inhibitors / pharmacology; Diarrhea / parasitology; Diarrhea / physiopathology; Diarrhea / therapy; Dietary Supplements; Disease Models, Animal; Enteral Nutrition; Ileum / parasitology; Ileum / pathology; Ileum / physiology; Indomethacin / pharmacology; Intestinal Mucosa / parasitology; Intestinal Mucosa / pathology; Nitric Oxide / biosynthesis; Oocysts / growth & development; Parasite Egg Count; Prostaglandins / biosynthesis; Random Allocation; Severity of Illness Index; Swine
TL;DR:
These studies demonstrate that provision of additional NO substrate in the form of L-arginine incites prostaglandin-dependent secretory diarrhea and does not promote epithelial defense or barrier function of C parvum–infected neonatal ileum.
(via Semantic Scholar)
open access via europepmc.org (repository)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries, Crossref, ORCID
Added: August 6, 2018
2008 journal article
The density of small tight junction pores varies among cell types and is increased by expression of claudin-2
Journal of Cell Science, 121(3), 298–305.
author keywords: claudin; tight junctions; paracellular permeability
MeSH headings : Animals; Biological Transport, Active; Caco-2 Cells; Cell Line; Claudin-4; Claudins; Dogs; Humans; LLC-PK1 Cells; Membrane Proteins / antagonists & inhibitors; Membrane Proteins / genetics; Membrane Proteins / metabolism; Particle Size; Polyethylene Glycols / chemistry; Polyethylene Glycols / pharmacokinetics; Recombinant Proteins / genetics; Recombinant Proteins / metabolism; Swine; Tight Junctions / metabolism; Tight Junctions / ultrastructure; Transfection
TL;DR:
It is speculated that permeability of all small solutes is proportional to pore number but that small electrolytes are subject to further selectivity by the profile of claudins expressed, explaining the dissociation between the Papp for noncharged solutes and electrical resistance.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, Crossref, NC State University Libraries
Added: August 6, 2018
2007 journal article
Efficacy of tinidazole for treatment of cats experimentally infected with Tritrichomonas foetus
AMERICAN JOURNAL OF VETERINARY RESEARCH, 68(10), 1085–1088.
MeSH headings : Animals; Antitrichomonal Agents / therapeutic use; Cat Diseases / drug therapy; Cat Diseases / parasitology; Cats; Dose-Response Relationship, Drug; Protozoan Infections / drug therapy; Tinidazole / therapeutic use; Tritrichomonas foetus / isolation & purification
TL;DR:
Although tinidazole decreased the detection of T foetus and treated cats were resistant to later efforts to incite the infection, inability of tinidrazole to eradicate infection in many cats poses a serious impediment to the drug's effectiveness in practice.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
5. Gender Equality
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2007 journal article
Optimization of a species-specific polymerase chain reaction assay for identification of Pentatrichomonas hominis in canine fecal specimens
AMERICAN JOURNAL OF VETERINARY RESEARCH, 68(7), 783–787.
MeSH headings : Animals; DNA, Protozoan / chemistry; DNA, Protozoan / genetics; Diarrhea / diagnosis; Diarrhea / parasitology; Dog Diseases / diagnosis; Dog Diseases / parasitology; Dogs; Feces / parasitology; Female; Male; Polymerase Chain Reaction / methods; Polymerase Chain Reaction / veterinary; Protozoan Infections, Animal / diagnosis; Protozoan Infections, Animal / parasitology; Species Specificity; Trichomonadida / genetics; Trichomonadida / isolation & purification
TL;DR:
Molecular identification of P hominis in feces of 4 dogs with trichomonosis and diarrhea reported here validates the identity of this species in such infections.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
5. Gender Equality
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018