Works (7)

Updated: July 5th, 2023 15:54

2013 journal article

Developing Predictive Approaches to Characterize Adaptive Responses of the Reproductive Endocrine Axis to Aromatase Inhibition: II. Computational Modeling

TOXICOLOGICAL SCIENCES, 133(2), 234–247.

By: M. Breen n, D. Villeneuve*, G. Ankley*, D. Bencic*, M. Breen*, K. Watanabe*, A. Lloyd n, R. Conolly*

co-author countries: United States of America 🇺🇸
author keywords: endocrine disruptors; biological modeling; non-mammalian species; dose response; biomarkers
MeSH headings : Adaptation, Physiological / drug effects; Animal Testing Alternatives; Animals; Aromatase Inhibitors / toxicity; Computer Simulation; Cyprinidae / physiology; Dose-Response Relationship, Drug; Estradiol / blood; Estrogen Antagonists / toxicity; Fadrozole / toxicity; Female; Hypothalamo-Hypophyseal System / drug effects; Hypothalamo-Hypophyseal System / enzymology; Male; Ovary / drug effects; Ovary / enzymology; Predictive Value of Tests; Time Factors
Source: Web Of Science
Added: August 6, 2018

2013 journal article

Developing predictive approaches to characterize adaptive responses of the reproductive endocrine axis to Aromatase inhibition: I. Data generation in a small fish model

Toxicological Sciences, 133(2), 225–233.

By: D. Villeneuve, M. Breen, D. Bencic, J. Cavallin, K. Jensen, E. Makynen, L. Thomas, L. Wehmas, R. Conolly, G. Ankley

Source: NC State University Libraries
Added: August 6, 2018

2011 journal article

Mechanistic Computational Model of Steroidogenesis in H295R Cells: Role of Oxysterols and Cell Proliferation to Improve Predictability of Biochemical Response to Endocrine Active Chemical-Metyrapone

TOXICOLOGICAL SCIENCES, 123(1), 80–93.

By: M. Breen n, M. Breen*, N. Terasaki, M. Yamazaki, A. Lloyd n & R. Conolly*

co-author countries: United States of America 🇺🇸
author keywords: endocrine disrupting chemicals; mechanistic computational model; in vitro toxicology; metyrapone; H295R cells; steroid biosynthesis
MeSH headings : Adrenocortical Carcinoma / drug therapy; Adrenocortical Carcinoma / metabolism; Cell Line, Tumor; Cell Proliferation / drug effects; Cell Survival / drug effects; Cholesterol / analogs & derivatives; Cholesterol / metabolism; Computational Biology / methods; Endocrine Disruptors / toxicity; Enzyme Inhibitors / toxicity; Humans; Metyrapone / toxicity; Models, Theoretical; Predictive Value of Tests; Steroids / metabolism
Source: Web Of Science
Added: August 6, 2018

2011 conference paper

Predicting chemical impacts on vertebrate endocrine systems

Environmental Toxicology and Chemistry, 30(1), 39–51.

By: J. Nichols, M. Breen, R. Denver, J. Distefano, J. Edwards, R. Hoke, D. Volz, X. Zhang

Source: NC State University Libraries
Added: August 6, 2018

2010 journal article

Computational model of steroidogenesis in humanH295R cells to predict biochemical response to endocrine-active chemicals: Model development for metyrapone

Environmental Health Perspectives, 118(2), 265–272.

By: M. Breen, M. Breen, N. Terasaki, M. Yamazaki & R. Conolly

Source: NC State University Libraries
Added: August 6, 2018

2010 journal article

Predicting Residential Air Exchange Rates from Questionnaires and Meteorology: Model Evaluation in Central North Carolina

ENVIRONMENTAL SCIENCE & TECHNOLOGY, 44(24), 9349–9356.

By: M. Breen n, M. Breen n, R. Williams n & B. Schultz n

co-author countries: United States of America 🇺🇸
MeSH headings : Air Movements; Air Pollutants / analysis; Air Pollution, Indoor / analysis; Air Pollution, Indoor / statistics & numerical data; Atmosphere / chemistry; Environmental Monitoring / methods; Forecasting; Meteorological Concepts; Models, Chemical; North Carolina; Particle Size; Seasons; Surveys and Questionnaires
Source: Web Of Science
Added: August 6, 2018

2007 journal article

MRI-guided thermal ablation therapy: Model and parameter estimates to predict cell death from MR thermometry images

ANNALS OF BIOMEDICAL ENGINEERING, 35(8), 1391–1403.

By: M. Breen*, M. Breen n, K. Butts*, L. Chen*, G. Saidel* & D. Wilson*

co-author countries: United States of America 🇺🇸
author keywords: cell death model; interventional MRI; laser thermal ablation; MR thermometry
MeSH headings : Animals; Brain; Brain Neoplasms / therapy; Cell Death / physiology; Laser Therapy; Magnetic Resonance Imaging / methods; Models, Theoretical; Rabbits; Temperature
Source: Web Of Science
Added: August 6, 2018