Works (15)

Updated: April 11th, 2023 10:13

2020 journal article

Role of long non-coding RNA in DEET- and fipronil-mediated alteration of transcripts associated with Phase I and Phase II xenobiotic metabolism in human primary hepatocytes

PESTICIDE BIOCHEMISTRY AND PHYSIOLOGY, 167.

By: R. Lawrie, R. Mitchell, A. Dhammi, A. Wallace, E. Hodgson & R. Roe

author keywords: Long non-coding RNA; DEET; Fipronil; Xenobiotic metabolism; Environmental chemicals; Cytochrome P450
Sources: Web Of Science, ORCID
Added: July 6, 2020

2017 journal article

Differential Expression Profile of lncRNAs from Primary Human Hepatocytes Following DEET and Fipronil Exposure

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 18(10).

By: R. Mitchell, A. Wallace, E. Hodgson & R. Roe

author keywords: DEET; fipronil; long non-coding RNA; lncRNA; primary liver cells; epigenetics; RNA-Seq; transcriptomics; Zika virus; human hepatocytes
Sources: Web Of Science, ORCID
Added: August 6, 2018

2016 journal article

Impact of Environmental Chemicals on the Transcriptome of Primary Human Hepatocytes: Potential for Health Effects

Journal of Biochemical and Molecular Toxicology, 30(8), 375–395.

By: R. Mitchell, A. Dhammi, A. Wallace, E. Hodgson & R. Roe

author keywords: DEET; Fipronil; Gene expression; Human hepatocytes; RNA-Seq; Endocrine System; P450
Sources: Web Of Science, Crossref, ORCID
Added: August 6, 2018

2014 journal article

Human Variation and Risk Assessment: Microarray and Other Studies Utilizing Human Hepatocytes and Human Liver Subcellular Preparations

JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY, 28(1), 1–10.

By: E. Hodgson, A. Wallace, R. Shah*, K. Choi & H. Joo

author keywords: Cytotoxicity; Human Hepatocytes; Human Variation; Microarrays; RNAseq; Toxicant Metabolism; Toxicant Interactions
Source: Web Of Science
Added: August 6, 2018

2012 journal article

DNA methylation alterations in response to pesticide exposure in vitro

Environmental and Molecular Mutagenesis, 53(7), 542–549.

By: X. Zhang, A. Wallace, P. Du, W. Kibbe, N. Jafari, H. Xie, S. Lin, A. Baccarelli, M. Soares, L. Hou

Source: NC State University Libraries
Added: August 6, 2018

2012 journal article

Genome-wide study of DNA methylation alterations in response to diazinon exposure in vitro

Environmental Toxicology and Pharmacology, 34(3), 959–968.

By: X. Zhang, A. Wallace, P. Du, S. Lin, A. Baccarelli, H. Jiang, N. Jafari, Y. Zheng ...

Source: NC State University Libraries
Added: August 6, 2018

2012 review

Toxic endpoints in the study of human exposure to environmental chemicals

[Review of ]. Toxicology and human environments, 112, 89–115.

By: A. Wallace

Source: NC State University Libraries
Added: August 6, 2018

2010 journal article

Endosulfan induces CYP2B6 and CYP3A4 by activating the pregnane X receptor

Toxicology and Applied Pharmacology, 245(3), 335–343.

By: R. Casabar, P. Das, G. DeKrey, C. Gardiner, Y. Cao, R. Rose, A. Wallace

Source: NC State University Libraries
Added: August 6, 2018

2010 journal article

Human variation in CYP-specific chlorpyrifos metabolism

TOXICOLOGY, 276(3), 184–191.

By: E. Croom, A. Wallace & E. Hodgson

author keywords: Chlorpyrifos; CYP isoform; Desulfuration; Dearylation; Human liver microsomes; Organophosphorothioate pesticides
Source: Web Of Science
Added: August 6, 2018

2010 journal article

Interactions of the crustacean nuclear receptors HR3 and E75 in the regulation of gene transcription

GENERAL AND COMPARATIVE ENDOCRINOLOGY, 167(2), 268–278.

By: B. Hannas, Y. Wang, W. Baldwin*, Y. Li*, A. Wallace & G. LeBlanc

author keywords: Daphnia pulex; Ecdysteroids; Endocrine disruptor; Nuclear receptors
Sources: Web Of Science, ORCID
Added: August 6, 2018

2010 journal article

Lysine 419 targets human glucocorticoid receptor for proteasomal degradation

Steroids, 75(12), 1016–1023.

By: A. Wallace, Y. Cao, S. Chandramouleeswaran & J. Cidlowski

Source: NC State University Libraries
Added: August 6, 2018

2009 journal article

Human hepatic CYP2B6 developmental expression: The impact of age and genotype

BIOCHEMICAL PHARMACOLOGY, 78(2), 184–190.

By: E. Croom, J. Stevens*, R. Hines*, A. Wallace & E. Hodgson

author keywords: CYP450; Ontogeny; CYP2B6; CYP3A; Hepatic
Source: Web Of Science
Added: August 6, 2018

2008 journal article

Phthalate induction of CYP3A4 is dependent on glucocorticoid regulation of PXR expression

TOXICOLOGICAL SCIENCES, 103(2), 268–277.

By: B. Cooper n, T. Cho, P. Thompson & A. Wallace

author keywords: pregnane X receptor; CYP3A4; DEHP; MEHP; glucocorticoid
Sources: Web Of Science, ORCID
Added: August 6, 2018

2008 journal article

Unique transcription start sites and distinct promoter regions differentiate the pregnane X receptor (PXR) isoforms PXR 1 and PXR 2

DRUG METABOLISM AND DISPOSITION, 36(5), 923–929.

By: L. Tompkins, T. Sit & A. Wallace

Sources: Web Of Science, ORCID
Added: August 6, 2018

2007 journal article

Mechanisms of cytochrome P450 induction

Journal of Biochemical and Molecular Toxicology, 21(4), 176–181.

By: L. Tompkins & A. Wallace

Source: NC State University Libraries
Added: August 6, 2018