Andrew D. Wallace

Works (15)

Updated: July 5th, 2023 15:53
Download BibTeX Download Plain Text View JSON

2020 journal article

Role of long non-coding RNA in DEET- and fipronil-mediated alteration of transcripts associated with Phase I and Phase II xenobiotic metabolism in human primary hepatocytes

PESTICIDE BIOCHEMISTRY AND PHYSIOLOGY, 167.

By: R. Lawrie n, R. Mitchell n, A. Dhammi n, A. Wallace n, E. Hodgson n & R. Roe n 

co-author countries: United States of America 🇺🇸
author keywords: Long non-coding RNA; DEET; Fipronil; Xenobiotic metabolism; Environmental chemicals; Cytochrome P450
MeSH headings : DEET; Hepatocytes; Humans; Insect Repellents; Pyrazoles; RNA, Long Noncoding
Sources: Web Of Science, ORCID
Added: July 6, 2020

2017 journal article

Differential Expression Profile of lncRNAs from Primary Human Hepatocytes Following DEET and Fipronil Exposure

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 18(10).

By: R. Mitchell n, A. Wallace n, E. Hodgson n & R. Roe n 

co-author countries: United States of America 🇺🇸
author keywords: DEET; fipronil; long non-coding RNA; lncRNA; primary liver cells; epigenetics; RNA-Seq; transcriptomics; Zika virus; human hepatocytes
MeSH headings : Cells, Cultured; DEET / pharmacology; Epigenomics / methods; Hepatocytes / drug effects; Hepatocytes / metabolism; Humans; Pyrazoles / pharmacology; RNA, Long Noncoding / genetics; Zika Virus / genetics
Sources: Web Of Science, ORCID
Added: August 6, 2018

2016 journal article

Impact of Environmental Chemicals on the Transcriptome of Primary Human Hepatocytes: Potential for Health Effects

Journal of Biochemical and Molecular Toxicology, 30(8), 375–395.

By: R. Mitchell n, A. Dhammi n, A. Wallace n, E. Hodgson n & R. Roe n 

co-author countries: United States of America 🇺🇸
author keywords: DEET; Fipronil; Gene expression; Human hepatocytes; RNA-Seq; Endocrine System; P450
MeSH headings : Chromosome Mapping; DEET / toxicity; Drug Combinations; Genome, Human; Hepatocytes / cytology; Hepatocytes / drug effects; Hepatocytes / metabolism; Humans; Insect Repellents / toxicity; Insecticides / toxicity; Molecular Sequence Annotation; Primary Cell Culture; Pyrazoles / toxicity; Sequence Analysis, RNA; Transcriptome / drug effects
Sources: Web Of Science, Crossref, ORCID
Added: August 6, 2018

2014 journal article

Human Variation and Risk Assessment: Microarray and Other Studies Utilizing Human Hepatocytes and Human Liver Subcellular Preparations

JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY, 28(1), 1–10.

By: E. Hodgson n, A. Wallace n, R. Shah*, K. Choi n & H. Joo n

co-author countries: United States of America 🇺🇸
author keywords: Cytotoxicity; Human Hepatocytes; Human Variation; Microarrays; RNAseq; Toxicant Metabolism; Toxicant Interactions
MeSH headings : Enzyme Activation; Enzyme Inhibitors / pharmacology; Genetic Variation; Hepatocytes / enzymology; Hepatocytes / metabolism; Humans; Liver / metabolism; Oligonucleotide Array Sequence Analysis; Risk Assessment; Subcellular Fractions / metabolism
Source: Web Of Science
Added: August 6, 2018

2012 journal article

DNA methylation alterations in response to pesticide exposure in vitro

Environmental and Molecular Mutagenesis, 53(7), 542–549.

By: X. Zhang, A. Wallace, P. Du, W. Kibbe, N. Jafari, H. Xie, S. Lin, A. Baccarelli, M. Soares, L. Hou

Source: NC State University Libraries
Added: August 6, 2018

2012 journal article

Genome-wide study of DNA methylation alterations in response to diazinon exposure in vitro

Environmental Toxicology and Pharmacology, 34(3), 959–968.

By: X. Zhang, A. Wallace, P. Du, S. Lin, A. Baccarelli, H. Jiang, N. Jafari, Y. Zheng ...

Source: NC State University Libraries
Added: August 6, 2018

2012 review

Toxic endpoints in the study of human exposure to environmental chemicals

[Review of ]. Toxicology and human environments, 112, 89–115.

By: A. Wallace

Source: NC State University Libraries
Added: August 6, 2018

2010 journal article

Endosulfan induces CYP2B6 and CYP3A4 by activating the pregnane X receptor

Toxicology and Applied Pharmacology, 245(3), 335–343.

By: R. Casabar, P. Das, G. DeKrey, C. Gardiner, Y. Cao, R. Rose, A. Wallace

Source: NC State University Libraries
Added: August 6, 2018

2010 journal article

Human variation in CYP-specific chlorpyrifos metabolism

TOXICOLOGY, 276(3), 184–191.

By: E. Croom*, A. Wallace* & E. Hodgson*

author keywords: Chlorpyrifos; CYP isoform; Desulfuration; Dearylation; Human liver microsomes; Organophosphorothioate pesticides
MeSH headings : Animals; Aryl Hydrocarbon Hydroxylases / metabolism; Cell Line; Chlorpyrifos / metabolism; Chlorpyrifos / toxicity; Cytochrome P-450 CYP2B6; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP3A / metabolism; Cytochrome P-450 Enzyme System / genetics; Cytochrome P-450 Enzyme System / metabolism; Humans; Insecticides / metabolism; Insecticides / toxicity; Isoenzymes / genetics; Isoenzymes / metabolism; Microsomes, Liver / drug effects; Microsomes, Liver / enzymology; Oxidoreductases, N-Demethylating / metabolism; Substrate Specificity / drug effects; Substrate Specificity / physiology
Source: Web Of Science
Added: August 6, 2018

2010 journal article

Interactions of the crustacean nuclear receptors HR3 and E75 in the regulation of gene transcription

GENERAL AND COMPARATIVE ENDOCRINOLOGY, 167(2), 268–278.

By: B. Hannas n, Y. Wang n, W. Baldwin *, Y. Li*, A. Wallace n & G. LeBlanc n 

co-author countries: United States of America 🇺🇸
author keywords: Daphnia pulex; Ecdysteroids; Endocrine disruptor; Nuclear receptors
Sources: Web Of Science, ORCID
Added: August 6, 2018

2010 journal article

Lysine 419 targets human glucocorticoid receptor for proteasomal degradation

Steroids, 75(12), 1016–1023.

By: A. Wallace, Y. Cao, S. Chandramouleeswaran & J. Cidlowski

Source: NC State University Libraries
Added: August 6, 2018

2009 journal article

Human hepatic CYP2B6 developmental expression: The impact of age and genotype

BIOCHEMICAL PHARMACOLOGY, 78(2), 184–190.

By: E. Croom n, J. Stevens*, R. Hines*, A. Wallace n & E. Hodgson n

co-author countries: United States of America 🇺🇸
author keywords: CYP450; Ontogeny; CYP2B6; CYP3A; Hepatic
MeSH headings : Adolescent; Age Factors; Aryl Hydrocarbon Hydroxylases / biosynthesis; Aryl Hydrocarbon Hydroxylases / chemistry; Aryl Hydrocarbon Hydroxylases / genetics; Child; Child, Preschool; Cytochrome P-450 CYP2B6; Female; Gene Expression Regulation, Developmental / physiology; Gene Expression Regulation, Enzymologic / physiology; Genotype; Humans; Infant; Male; Microsomes, Liver / enzymology; Oxidoreductases, N-Demethylating / biosynthesis; Oxidoreductases, N-Demethylating / chemistry; Oxidoreductases, N-Demethylating / genetics
Source: Web Of Science
Added: August 6, 2018

2008 journal article

Phthalate induction of CYP3A4 is dependent on glucocorticoid regulation of PXR expression

TOXICOLOGICAL SCIENCES, 103(2), 268–277.

By: B. Cooper n, T. Cho n, P. Thompson n  & A. Wallace n

co-author countries: United States of America 🇺🇸
author keywords: pregnane X receptor; CYP3A4; DEHP; MEHP; glucocorticoid
MeSH headings : Animals; Carcinoma, Hepatocellular; Cell Line, Tumor; Cytochrome P-450 CYP3A / biosynthesis; Dexamethasone / pharmacology; Diethylhexyl Phthalate / analogs & derivatives; Diethylhexyl Phthalate / toxicity; Dose-Response Relationship, Drug; Drug Synergism; Enzyme Induction / drug effects; Glucocorticoids / pharmacology; Hepatocytes / drug effects; Hepatocytes / metabolism; Humans; Plasticizers / toxicity; Pregnane X Receptor; Rats; Receptors, Steroid / drug effects; Receptors, Steroid / metabolism; Transcription, Genetic / drug effects; Transfection
Sources: Web Of Science, ORCID
Added: August 6, 2018

2008 journal article

Unique transcription start sites and distinct promoter regions differentiate the pregnane X receptor (PXR) isoforms PXR 1 and PXR 2

DRUG METABOLISM AND DISPOSITION, 36(5), 923–929.

By: L. Tompkins*, T. Sit*  & A. Wallace*

Contributors: L. Tompkins*, T. Sit*  & A. Wallace*

MeSH headings : Cell Line, Tumor; Cytochrome P-450 CYP3A / genetics; Gene Expression; Humans; Liver / metabolism; Pregnane X Receptor; Promoter Regions, Genetic; Protein Isoforms / genetics; RNA, Messenger / metabolism; Receptors, Cytoplasmic and Nuclear; Receptors, Steroid / genetics; Reverse Transcriptase Polymerase Chain Reaction; Transcription Initiation Site; Transfection
Sources: Web Of Science, ORCID
Added: August 6, 2018

2007 journal article

Mechanisms of cytochrome P450 induction

Journal of Biochemical and Molecular Toxicology, 21(4), 176–181.

By: L. Tompkins & A. Wallace

Source: NC State University Libraries
Added: August 6, 2018