Jonathan Kirk Harris

Works (3)

Updated: July 5th, 2023 16:02

2005 journal article

Structural implications of novel diversity in eucaryal RNase P RNA

RNA, 11(5), 739–751.

By: S. Marquez, J. Harris, S. Kelley, J. Brown, S. Dawson, E. Roberts, N. Pace

Source: NC State University Libraries
Added: August 6, 2018

2001 journal article

New insight into RNase P RNA structure from comparative analysis of the archaeal RNA

RNA, 7(2), 220–232.

By: J. Harris n, E. Haas n, D. Williams  n, D. Frank * & J. Brown n

author keywords: Archaea; archaebacteria; ribonuclease P; ribozyme; rnpB
MeSH headings : Base Sequence; Cells, Cultured; DNA Primers / chemistry; Endoribonucleases / chemistry; Escherichia coli / enzymology; Escherichia coli / genetics; Escherichia coli Proteins; Genes, Bacterial / genetics; Molecular Sequence Data; Nucleic Acid Conformation; Phylogeny; Plasmids; Polymerase Chain Reaction; RNA, Archaeal / classification; RNA, Archaeal / genetics; RNA, Bacterial / chemistry; RNA, Bacterial / isolation & purification; RNA, Catalytic / chemistry; RNA, Catalytic / isolation & purification; Ribonuclease P; Sequence Alignment; Sequence Analysis, DNA
TL;DR: A detailed comparative analysis of archaeal RNase P RNA structure and a comparison of the resulting structural information with that of the bacterial RNA reveals that the ArchaealRNase P RNAs are strikingly similar to those of Bacteria. (via Semantic Scholar)
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Source: Web Of Science
Added: August 6, 2018

1999 journal article

RNase P RNAs from some Archaea are catalytically active

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 96(14), 7803–7808.

By: J. Pannucci n, E. Haas n, T. Hall n, J. Harris n & J. Brown n

MeSH headings : Archaea / enzymology; Archaea / genetics; Bacillus / enzymology; Bacillus / genetics; Base Sequence; Conserved Sequence; Endoribonucleases / chemistry; Endoribonucleases / genetics; Endoribonucleases / metabolism; Kinetics; Methanobacterium / enzymology; Methanobacterium / genetics; Models, Molecular; Molecular Sequence Data; Nucleic Acid Conformation; Phylogeny; RNA, Archaeal / chemistry; RNA, Archaeal / genetics; RNA, Archaeal / metabolism; RNA, Bacterial / metabolism; RNA, Catalytic / chemistry; RNA, Catalytic / genetics; RNA, Catalytic / metabolism; Ribonuclease P
TL;DR: The properties of the archaeal RNase P RNAs (high ionic-strength requirement, low affinity for substrate, and catalytic reconstitution by bacterialRNase P protein) are similar to synthetic RNases that contain all of the catalytic core of the bacterial RNA but lack phylogenetically variable, stabilizing elements. (via Semantic Scholar)
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Source: Web Of Science
Added: August 6, 2018

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