Works (1)
Updated: July 5th, 2023 15:49
2009 journal article
Chlorotriazine Herbicides and Metabolites Activate an ACTH-dependent Release of Corticosterone in Male Wistar Rats
TOXICOLOGICAL SCIENCES, 112(1), 78–87.
author keywords: atrazine; simazine; propazine; adrenal; steroidogenesis; ACTH; corticosterone
MeSH headings : Adrenocorticotropic Hormone / drug effects; Adrenocorticotropic Hormone / physiology; Animals; Corticosterone / metabolism; Dose-Response Relationship, Drug; Herbicides / blood; Herbicides / toxicity; Male; Radioimmunoassay; Rats; Rats, Wistar; Triazines / blood; Triazines / toxicity
TL;DR:
The rapid release of ACTH and subsequent activation of adrenal steroidogenesis following a single exposure to ATR, SIM, PRO, DIA, or DEA may reflect chlorotriazine-induced changes at the level of the brain and/or pituitary.
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